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At each end of a long bone is an expanded portion; end of long bone;mainly spongy bone |
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shaft of the bone; alot of compact bone; has the medullar cavity |
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widening part of the bone between the diaphysis and the epiphysis |
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cortical bone, wall of the diaphysis is mainly composed of tighlty packed tissue; has osteons |
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cancellous bone, in the epiphyses that have thin layers of compact bone on their surfaces; made of trabeculae |
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on its outer surface, the articulating portion of the epiphysis is coated with a layer of hyaline cartilage |
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tough, vascular covering of dense connective tissue; surrounds the bone |
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a thin memmbrane containing bone forming cells; inner lining of medullar cavity |
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semirigid tube with a hollow chamber; found in the compact bone in the diaphysis of a long bone; where yellow bone marrow is found |
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branching bony plates; found in spongy bone |
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Mature bone cells;transport nutrients and wastes |
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extracellular matrix of bone |
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largely collagen and inorganic salts
Collagen gives bone resilience; Inorganic salts make bone hard |
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function and structural unit of compact bone |
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horizontal canals that connect the central canal |
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vertical canal, have blood vessels and nerves, found within osteon |
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layers that form each osteon |
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chamber where osteocytes are found |
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osteocytes intensions that allow them to communicate with one another |
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band of cartilage that remains between the 2 ossification centers |
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blood cell formation that begins in the yolk sac |
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openign for blood vessels |
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enlargement on the bone end |
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• Gives shape to head, etc.
• Supports body’s weight
• Protects lungs, etc.
• Bones and muscles interact when limbs or body parts move |
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Spongy bone versus compact bone |
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Spongy
With air spaces
Has red bone marrow
Makes up all the red blood cells
Not solid
Compact Bone- solid, dense; forms the hollow shaft of long bones; has yellow bone marrow(stores fat) |
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Difference between intramembranous bone and endochondral bones |
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Intramembranous Ossification
These bones originate within sheetlike layers of connective tissues;They are the broad, flat bones;Flat bones of the skull, clavicles, sternum, and some facial bones; Osteoblasts are born forming cells
Endochondral Ossification
Bones begin as hyaline cartilage; Form models for future bones; These are most bones of the skeleton; Cartilage cells die and breakdown; Periosteum forms;Osteoblasts begin to form spongy bone;Then compact bone is deposited
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Understand the growth at the epiphyseal plate (4 zones) |
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Zone of resting cartilage (1
st layer of cells); Closest to the end of epiphysis; Resting cells;Anchors epiphyseal plate to epiphysis;
Zone of proliferating cartilage (2
nd layer of cells); Many rows of young cells; Undergoing mitosis
Zone of hypertrophic cartilage (3rd layer of cells); Older cells ;Left behind when new cells appear; Cells enlarging and becoming calcified
Zone of calcified cartilage (4th layer of cells); Thin;Dead cells; Calcified extracellular matrix |
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Which ions are found in the extracellular matrix of bone? |
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Magnesium ions; Sodium ions; Potassium ions; Carbonate ions |
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Bones of axial and appendicular skeleton |
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• Axial Skeleton
• Skull
•Vertebral column
• Hyoid bone
• Thoracic cage
• Appendicular Skeleton
• Pectoral girdle
• Upper limbs
• Pelvic girdle
• Lower limbs |
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the study of muscloskeletal movement |
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Most complex; allow free movement
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Structural Classification of joints- 1) Fibrous 2) Cartilaginous 3) Synovial |
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1) Fibrous joints
Dense connective tissues connect
bones
Between bones in close contact
(2) Cartilaginous joints
Hyaline cartilage or fibrocartilage
connect bones
(3) Synovial joints
Most complex
Allow free movement
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Functional Classification of joints- 1) Synarthrotic 2) Amphiarthrotic 3) Diarthrotic |
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• Synarthrotic joints
considered immovable
•Amphiarthrotic joints
Slightly movable
• Diarthrotic joints
Freely movable
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- 3 types of Fibrous joints 1) Syndesmosis 2) Suture 3) Gomphosis |
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• Syndesmosis:
A sheet or bundle of fibrous tissue connecting bones
Lies between tibia and fibula
Amphiarthritic
Suture:
Between flat bones
Teeth-like projections
Thin layer of connective tissue connects bones
Skull
synarthritic
•Gomphosis:
Cone-shaped bony process in a socket
Tooth in jawbone
Synarthritic
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- 2 types of Cartilaginous joints 1) Synchondrosis 2) Symphysis |
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• Synchondrosis:
Bands of hyaline cartilage unite bones
Between manubrium and the first rib (costal cartilages)
Between the costal cartilage and the sternum
Synovial
Epiphyseal plates (temporary joints)
Synostosis – a bony joint
Synarthotic
•Symphysis:
Pad of fibrocartilage between bones
Pubic symphysis
Joint between bodies of adjacent vertbrae |
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Know the functions of the following specific parts of a synovial joint: articular cartilage |
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rim of the hyaline cartilage found in the embryonic skelton |
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Know the functions of the following specific parts of a synovial joint: joint cavity |
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within joint capsule, includes the synovial membrane and synovial fluid |
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Know the functions of the following specific parts of a synovial joint: joint capsule |
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keeps everything together, holds the whole synovial joint together; outside is dense, rest is loose |
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Know the functions of the following specific parts of a synovial joint: synovial membrane |
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inner layer of the joint capsule consists of shiny, vascular ling of loose connective tissue |
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Know the functions of the following specific parts of a synovial joint: synovial fluid |
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clear, viscious fluid that is secreted by the membrane; reduces friction and compression; tissue and white blood cell fluid |
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Know the functions of the following specific parts of a synovial joint: meniscus |
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parts of synovial joints that partially or completely divide into 2 compartments by discs of fibrocartilage between articular surfaces |
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Know the functions of the following specific parts of a synovial joint: bursae |
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fluid-filled sacs; inner lining of synovial membrane |
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Know examples (locations in the body) of the following types of synovial joints: ball and socket |
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- Know examples (locations in the body) of the following types of synovial joints: condylar |
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between metacarpals and phalanges; Between radius and carpals
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- Know examples (locations in the body) of the following types of synovial joints: gliding, |
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Between carpals
Between tarsals
Between facets of adjacent vertebrae
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- Know examples (locations in the body) of the following types of synovial joints: hinge |
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Elbow joint
Between phalanges
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- Know examples (locations in the body) of the following types of synovial joints: pivot |
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between atlas (C1) and dens of axis (C2) |
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- Know examples (locations in the body) of the following types of synovial joints: saddle
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Between carpal and 1st metacarpal of thumb
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layers of dense connective tissue; separated from adjacent muscles; surrounds entire muscle; forms into tendons |
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formed by fascia that surrounds each muscle and may project beyond the ends of its muscle fibers; cordlike |
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layer of connective tissue that closely surrounds a skeletal muscle along with the fascia |
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broad,fibrous sheets; can attach to bone or the coverings of aadjacent muscles; facial muscles; sheetlike |
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another layer of connective tissue that extends inward from the epimysium and separates the muscle tissue into small sections; surrounds fascia within muscle |
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thin covering; lies within a layer of connective tissue; surrounds muscle fibers (cells) within fasciles |
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abundant,parallel,threadlike structures; functional units of muscle |
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part of myofibrils; thin filaments; type of protein |
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thick filaments; part of myofibrils; type of protein |
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membrane around the muscle cell(fiber) |
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fluid and all the organelles within the muscle fibers(cells); fluid in here is called cytosol |
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the functional contraction site of a muscle fiber; where we find striations |
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corresponds to the endoplasmic reticulum of other cells; major calcium holders; take calcium in from cytosol and store it in the triad |
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triad (cisternae and Transverse tubule), |
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A set of membranous channels that extend into the sarcoplasm as invaginations continue with the sarcolemma and contains extracellular fluid(T tubules); Each T tubule lies between two enlarged portions of the sarcoplasmic reticulim(cisternae); storage for calcium (triad) |
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appear in the center of the I bands |
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sliightly lighter central region consisting of thick filaments |
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the site of functional connection |
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neurons that control effectors, including skeletal muscle fibers |
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where nuclei and mitochondria are abundant and the sarcolemma is extensively folded |
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a small gap that separates the membrane of the neuron and the membrane of the muscle fiber |
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store neurotransmitters; tiny vesicles |
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chemicals at a synapse that neurons communicate with cells that they control |
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the contractile response of a single muscle fiber to a muslce impulse |
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Process by which individual twitches combine; Produces sustained contractions; Can lead to tetanic contractions |
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immovable end; closer to midline or approximate to the trunk |
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movable end;distal or further from the body |
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primarily responsible for movement |
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contraction causes movement in the opposite direction of the prime mover |
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Differences between the 3 types of muscle tissue |
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• Skeletal Muscle
Usually attached to bones; Voluntary; Somatic; Striated
• Smooth Muscle
Walls of most viscera, blood vessels and skin; Involuntary; Autonomic; Not striated
• Cardiac Muscle
Wall of heart;Involuntary; Autonomic; Striated
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Understand the neuromuscular junction |
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The neurotransmiter of acetyl choline are used to unlock the sodium gate on the post synaptic membrane. then,sodium enters the post synaptic membrane which allows the action potential to jump from the pre synaptic membrane(axon) to the post synaptic membrane(muscle). the action potiental goes down the sarcolemma and into the transverse tubules and triggers the SR to release calcium into cytosol. The calcium is used to remove troponin and tropomyosin and for a bond betwen actin and myosin filaments. |
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- Understand how a muscle contracts and relaxes on the molecular level. Excitation-Contraction Coupling along with Cross Bridge Cycling |
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Two energy sources used for muscle contraction |
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1) Creatine phosphate
2) Cellular respiration |
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Difference between slow, fast, and intermediate fibers |
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Slow-twitch fibers (Type I)
Always oxidative; Resistant to fatigue; Red fibers; Most myoglobin; Good blood supply
Fast-twitch glycolytic fibers (Type IIb)
White fibers (less myoglobin); Poorer blood supply; Fewer michondria; More SR; Susceptible to fatigue
Fast-twitch fatigue-resistant fibers (Type IIa)
Intermediate fibers; Oxidative; Intermediate amount of myoglobin; Pink to red in color; Resistant to fatigue
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