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AP Biology
Chapter 13 (DNA)
15
Biology
12th Grade
04/27/2011

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Term
DNA
Definition
Deoxyribonucleic acid that is double stranded twisted into a helix shape, and it encodes the hereditary info for all living organisms.
Term
Bacteriophages
Definition
Infect certain bacteria; viruses.
Term
Nucleotide
Definition
Organic compound with a 5 carbon sugar, a nitrogenous base, and a phosphate group. T and C are pyrimidines and A and G are purines.
Term
DNA Replication
Definition
Process by which a cell duplicates its DNA molecules before division. It is semiconservative, which means that half of the nucleotides are new and half are old.
Term
Helicase
Definition
Type of enzyme that catalyzes the breaking of hydrogen bonds during DNA replication so the two strands of double helix can unwind.
Term
DNA polymerase
Definition
Enzyme that catalyzes the addition of free nucleotides to new DNA strands during replication; it also corrects mistakes in the genetic code.
Term
DNA ligase
Definition
Type of enzyme that catalyzes the sealing of short stretches of DNA into a continuous strand during replication and seals breaks
Term
DNA proofreading mechanisms
Definition
Any enzyme mediated process that fixes DNA replication errors or strand breaks
Term
Repair enzymes
Definition
Repairs nucleotide mismatches in DNA
Term
Earliest theories of genetics
Definition
Most researchers thought that proteins were the source of genetic variation because of the multitudes of ways amino acids can arrange themselves.
Term
The discovery of DNA
Definition
Watson and Crick built a model that fit all of the luces that they had learned so far. Rosalind Franklin was the first researcher to see the patterns of DNA, but her significance was overshadowed by Watson and Crick's discovery of the DNA structure.
Term
Duplication
Definition
The parent strands are unwound, proteins bind to them to keep from going back together, and polymerases build in the 5' to 3' direction.
Term
Embryo Cloning
Definition
Artificial twinning occurs in a lab; encourages the formation of twins, and the DNA is from 2 parents
Term
Adult Cloning
Definition
Nuclear transfer can replace the nucleus if an unfertilzed egg with a differentiated cell of an adult, and small electric shocks stimulate division.
Term
Therapeutic Cloning
Definition
Also uses nuclear transfers. DNA from a somatic cell is placed in a stem cell so that it becomes the cell that the DNA was taken from. It can help tissues regenerate.
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