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AP Biology Chapter 14
Simon Kenton
40
Biology
12th Grade
02/23/2012

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Term
RNA
Definition
Ribonucleic Acid
Term
Transcription occurs in the...
Definition
nucleus
Term
3 Types of of RNA...
Definition

1.  Messenger RNA (mRNA)

2.  Ribosomal RNA (rRNA)

3.  Transfer RNA (tRNA)

Term
mRNA
Definition
  • Messenger RNA
  • Transports the RNA from the nucleus to the ribosome
Term
rRNA
Definition

Ribosomal RNA

Makes Ribosomes

Term
tRNA
Definition

Transfer RNA

Transfers amino acids to ribosome

Term
What are the 4 nitrogen bases in RNA?
Definition

1.  adenine

2.  guanine

3.  cytosine

4.  uracil

Term
RNA contains the sugar...
Definition
ribose
Term
Transcription
Definition
The process of changing DNA into RNA
Term
RNA is a _____ stranded molecule.
Definition
Single
Term
What are the 3 steps in Transcription?
Definition

1. Initiation

2. Elongation

3. Termination

Term
What happens during initiation of transcription?
Definition
  • RNA polymerase attaches to the promoter on the DNA.
  • The promoter is TATA
Term
What happens during elongation of transcription?
Definition

RNA polymerase adds on RNA nucleotides in the 3' to 5' direction.

Term
What happens during termination of transcription?
Definition
RNA polymerase reaches a sequence of AAAAAAAAAA and transcription stops
Term

What 3 things needs to happen to the mRNA strand to become mature and then leave the nucleus?

Definition

1. Cap is added to the 5' end

2. A poly-A-tail is added to the 3' end

3. Introns are removed

Term
Introns
Definition

Non-coding regions of mRNA

Are removed befor the mRNA leaves the nucleus

Term
Exons
Definition
Coding regions of mRNA
Term
Codon
Definition

3 nucleotides on the mRNA strand

Also called a triplet

Codes for an amino acid

Term
Amino Acid
Definition

Building block of proteins

Carried on the tRNA

 

Term
How many possible codons?
Definition
64
Term
How many amino acids?
Definition
20
Term
What is the start codon and what amino acid does it code for?
Definition

AUG

methionine

Term
What are the 3 stop codons?
Definition
UAA, UAG, UGA
Term
Anticodon
Definition

3 nucleotides carried on the tRNA that pair with the codon.

Term
A tRNA has an _____ _____ attached at one end and _________ on the other end.
Definition

amino acid

anticodon

Term
Wobble Effect
Definition

When the tRNA binds to mRNA codon exact base pairing between the 3rd base does not have to be exact

Term
Ribosomes are made of...
Definition
a large subunit and a small subunit
Term
Translation
Definition
Process that takes a mRNA strand and changes it into an amino acid chain that codes for a protein.
Term
Where does translation take place?
Definition
Ribosome
Term
What are the 3 steps of Translation?
Definition

1.  Initiation

2. Elongation

3. Termination

Term
What occurs during initiation of translation?
Definition
  • mRNA binds to the small ribosomal subunit
  • finds an AUG
  • tRNA with anticodon UAC binds
  • Large ribosomal subunit attaches to the small subunit
Term
What occurs during elongation of translation?
Definition
  • AUG on the P site
  • The next mRNA codon on the A site binds with the tRNA anticodon.
  • The 2 amino acids form a peptide bond
  • The codon on the P site moves to the E site and the codon on the A site moves to the P site.
  • The next tRNA moves to the A site
Term
What occurs during termination of translation?
Definition
  • elongation continues until it reaches a stop codon
  • at termination a polypeptide chain is released and a protein is made
Term
Point Mutation or Base Pair Substitution
Definition
one base pair is replaced with another base pair
Term
2 Types of Point Mutations
Definition

1. Missense Mutation

2. Nonsense Mutation

Term
Missense Mutation
Definition
codons that still code for an amino acid, although it might not be the correct one
Term
Nonsense Mutation
Definition
Change a regular amino acid codon into a stop codon
Term
Frameshift Mutation
Definition
Base pair is added or deleted causing the codons to shift and change
Term
2 Types of Frameshift Mutations
Definition

1. Insertion

2. Deletion

Term
Transposons
Definition
DNA segments move spontaneously from one location to another in the same DNA molecule or to a different one
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