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Discovered that DNA is the genetic material |
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Took X-ray pictures of DNA |
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Discovered the structure of DNA
The 3 major features of DNA...
1. DNA is a double helix
2. 4 Nitrogen Bases
3. Strands are antiparallel
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DNA strands run in opposite directions |
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Deoxyribose
Phosphate
Nitrogen Bases |
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What is the backbone of DNA? |
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Deoxyribose and Phosphate |
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What are the 4 nitrogen bases in DNA? |
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1. Adenine
2. Guanine
3. Cytosine
4. Thymine |
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What joins the 2 strands of DNA together? |
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Made of deoxyribose, phosphate and nitrogen base |
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Single Ring
Ex: Thymine and Cytosine
Remember the Y's |
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Double Rings
Ex: Adenine and Guanine |
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Amount of A = T
Amount of C = G |
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Adenine bonds with Thymine
Cytosine bonds with Guanine |
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complementary
that means that A bonds with T and
C bonds with G |
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All species are made of A, T, C and G.
The only difference between species is... |
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how many nitrogen bases and in what order. |
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Making a copy of DNA
Occurs during the S phase of the cell cycle |
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Semiconservative Replication |
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After replication the 2 molecules of DNA will consist of an old strand and a new strand of DNA |
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What is the enzyme that unwinds and unzips the DNA for replication? |
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What is the enzyme that removes twists and knots that may form as the DNA is unziped? |
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What is the enzyme that adds on the the DNA nucleotides? |
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DNA Polymerase moves from... |
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The new complement strand of DNA grows in the... |
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The strand of DNA that goes from 3' to 5' in the same direction as the replication fork is the _____ strand. |
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Replication occurs fast as the DNA polymerase adds on nucleotides in the same direction it is unzipping.
This strand runs 3' to 5' |
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DNA polymerase moves away from the replication fork.
Is slower than the leading strand
DNA nucleotides are added in fragments |
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The strand of DNA that goes from 5' to 3' and in the opposite direction of the replication fork is called the _____ strand |
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Short segemnts of DNA made on the lagging strand during replication |
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Connects Okazaki segements to produce a single complementary strand of DNA |
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Special repair enzymes fix incorrectly paired nucleotides |
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Nucleotide Excision Repair |
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Incorrectly placed nucleotides are excised (removed) by enzymes called nucleases. |
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Short repetitive nucleotide sequences that do not contain genes at the ends of chromosomes |
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