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AP bio
Chapter 7-12
93
Biology
12th Grade
10/04/2009

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Term
Paracrine Signaling
Definition
Local. Lots of cells can recieve & respond to something produced by a single cell near them.
Term
Hormonal Communication
Definition
Greater distances. Specialized cells release hormone mols into circ. system, where they travel to target cells in other parts of the body.
Term
Three stages of cell signaling
Definition
Reception, Transduction, Response.
Term
Reception
Definition
Target cell's detection of a signal coming from outside the cell.
Term
Transduction
Definition
Initiated by signal binding to the protein, changing it's shape. Concerts signal to a form that can bring about the specific cellular response.
Term
Response
Definition
Transduced signal produces a specific cellular response. Cell signaling process helps make sure that important activities occur in right place, right time, etc.
Term
Tyrosine-kinase receptor
Definition
Attach phosphates to protein tyrosines. Need two signal molecules.
Term
Kinase proteins function
Definition
Transfers phosphate groups from ATP to a protein.
Term
General function of phosphatase proteins
Definition
Reverses effects of kinase proteins. Enzymes that remove phosphate groups from proteins.
Term
First messengers
Definition
Extracellular signal molecule that binds to the membrane receptor.
Term
Second messengers
Definition
Small, non protein, water soluble mols or ions. Signaling pathways.
Term
Two main second messengers
Definition
cAMP and calcium ions.
Term
Producing cAMP & deactivating it
Definition
Adenylyl cyclase activates and the first messenger causes a membrane enzyme to make cAMP. Another enzyme converts cAMP to AMP to deactivate it.
Term
Importance of elaborate pathways
Definition
Amplifies the cell's response to a signal. In each step, the # of activated products is much greater that the preceding step.
Term
Six major functions of membrane proteins
Definition
Transport, enzymatic activity, signal transduction, intercellular joining, cell-cell recognition, attachment to cytoskeleton & extracellular matrix (ECM).
Term
Change of a plant cell's plasma membrane in response to cold temperatures
Definition
The percentage of unsaturated phospholipids increases so it won't solidify in winter.
Term
Types of molecules that have difficulty crossing the plasma membrane
Definition
Charged atoms and ions. The charged atom and it's shell of water find the hydrophobic layer difficult to get through.
Term
Cell (plasma) membrane
Definition
B, P, A - Phospholipid bilayer. Selective barrier that allows passage of nutrients, ox, waste to service the entire cell.
Term
Cell Wall
Definition
B, P - Protects plant cell, maintains shape, prevents uptake of too much water, holds plant up against force of gravity. Thicker than plasma membrane. Primary cell wall, middle lumella, secondary cell wall.
Term
Cytoplasm
Definition
P, A - The space between the cell membrane and the nucleus.
Term
Cytoskeleton
Definition
P, A - Provides structural support, functions in mobility and motion, strands of protein.
Term
Centriole
Definition
P, A - Found within centrosome as a pair. Composed of 9 sets of triplet microtubules arranged ina ring. When cell divides, centrioles relicate. Help organize microtubule assembly. Not essential. Where spindle fibers form.
Term
Nucleus
Definition
P, A - Contains most of the genes that control the cell. Enclosed by nuclear envelope so it's separated from the cytoplasm.
Term
Nucleolus
Definition
P, A - Produces ribosomes.
Term
Nuclear Membrane (envelope)
Definition
P, A - Double membrane that encloses the nucleus, separating it from the cytoplasm. The two membranes are a lipid bilayer with associated proteins.
Term
Flagella, Cilia, or Pili
Definition
B, P, A - Locomotive appendages that protrude from some cells. Propel many unicellular euk. organisms through water. Cilia occur in large numbers on the cell surface. Flagella are limited to one or few per cell.
Term
Mitochondria & Chloroplasts
Definition
P, A & P - Membrane proteins are made by free ribosomes and their own ribosomes. Have small amounts of DNA. Grow and reproduce on their own within the cell. Have extra membrane. Endosymbiotic theory.
Term
Vacuole
Definition
P, A - Food vacuoles. Formed by phagocytosis. Contratile vacuole & central vacuole. Contractile in fresh water protozoans to keep water balance. Central found in most plant cells & stores organic compounds.
Term
Ribosomes
Definition
B, P, A - Assembly proteins. Free ribosomes are suspended in cytosol. Bound are attached to the ER. Structurally identical and interchangeable.
Term
Smooth ER
Definition
P, A - Production of lipids. No ribosomes attached.
Term
Rough ER
Definition
P, A - Produce proteins to be secreted from the cell. Ribosomes attached.
Term
Golgi Apparatus
Definition
P, A - Alters membrane phospholipids, modifies & stores & routes products of ER, targets products for parts of the cell.
Term
Lysosomes
Definition
P, A - Membrane bounded sac of hydrolytic enzymes that a cell uses to digest macromolecules. Works best in acid pH's. Maintains pH by pumping hydrogen ions from cytosol to lumen of lysosome.
Term
Plastids
Definition
P - Amyplasts store starch in roots and tubers. Chromoplasts are non-chlorophyll pigments responsible for non-green colors. Chloroplasts are chlorophyll containing plastids for photosynthesis.
Term
Vesicles
Definition
P, A - Transport vesicles, membrane bounded sacs within the cell.
Term
Endosymbiotic theory
Definition
For mitochondria. They were probably free living prok. cells when a larger cell engulfed them by phagocytosis, they weren't digested, and the larger cell stole it's energy.
Term
Endomembrane System
Definition
Plasma membrane, vesicles, golgi apparatus, vacuoles, lysosomes, rough ER, smooth ER, nucleus. Dynamic flow of membrane. Bit of __ can break off and become part of __ carried by vesicles.
Term
Peroxisome
Definition
Contains enzymes that transfer hydrogen from substrates to oxygen, producing hydrogen peroxide. In the liver they detoxify alcohol and other poisons.
Term
Microtubules
Definition
Cellular support, provides tracks for movement within the cell, composes cilia and flagella, separation of chromosomes during cell division (spindle fiber), composes centrioles in animal cells.
Term
Ideal osmotic environment for animal cells
Definition
Isotonic
Term
Ideal osmotic environment for plant cells
Definition
Hypotonic so they get turgid (very firm)
Term
Osmoregulation
Definition
Control of water balance. Helps freshwater protists control water intake. Plasma membrane is less permeable to water, slows uptake of water, pumps water out of a vacuole.
Term
How is cholesterol transported into human cells?
Definition
Receptor mediated endocytosis.
Term
Endocytosis
Definition
Cells absorb molecules from outside the cell by engulfing it with their cell membrane.
Term
What cholesterol does for cells
Definition
Membrane stablization. Increase the temp, increases cholesterol. Decrease the temp, decreases cholesterol.
Term
Co-transport
Definition
A single ATP powered pump transports a solute and indirectly drives the active transport of several other solutes.
Term
Symport
Definition
Movement of 2+ different molecules across the plasma membrane in the same direction.
Term
Antiport
Definition
Movement of 2+ different molecules across the plasma membrane in opposite directions.
Term
Chemiosis
Definition
Production of ATP using the energy of hydrogen ion gradients. Hydrogen ions want to flow back through.
Term
Why do phospholipids rarely flip-flop across the membrane?
Definition
The hydropphilic part would have to cross the hydrophobic core of the membrane.
Term
What types of molecules diffuse readily across the cell membrane?
Definition
Hydrophobic molecules because they can dissolve in the membrane.
Term
Current membrane model
Definition
Fluid mosaic model
Term
Fluid
Definition
Things can move around (solids can be fluid (ex: pile of corn kernels)).
Term
Mosaic
Definition
Lots of parts stuck together to make something bigger. Not uniform. Not the same in any region.
Term
Selective permeability
Definition
Some things can fit through and some can't.
Term
Amphipathic
Definition
Hydropphobic and hydrophilic regions.
Term
Membrane carbohydrates
Definition
Cell to cell recognition.
Term
Integral/peripheral proteins
Definition
Integral: In the membrane.
Peripheral: On the surface of the membrane.
Term
Diffusion
Definition
Tendency of any molecule to spreak out into available space.
Term
After equilibrium, water...
Definition
Does not stop diffusing.
Term
Passive transport
Definition
Diffusion of a substance across a biological membrane. No energy added to make it happen.
Term
Active transport
Definition
Movement of a substance against it's concentration gradient with the help of cellular energy.
Term
Facilitated diffusion
Definition
Form of passive transport facilitated by transport proteins. Passage of molecules or ions across the membrane passing through specific transmembrane transport proteins. High to low.
Term
Why cell division occurs
Definition
TO allow multicellular organisms to grow and develop, replace cells that die.
Term
Somatic cells
Definition
Diploids, all body cells except reproductive cells.
Term
Gametes
Definition
Haploids, reproductive sperm and egg cells.
Term
Relationship between chromatin and chromosomes
Definition
After a cell duplicates it's genome, chromatin condenses, making the chromosome very thick.
Term
Interphase
Definition
Chromosomes have already duplicated. Nucleus still well defined. Two centrosomes.
Term
Prophase
Definition
The chromatin condenses and the chromosomes become visible. Also the nucleolus disappears, the nuclear membrane fragments, and spindle fibers are assembled.
Term
Prometaphase
Definition
Envelope fragments, spindle can interact with chromosomes. Chromatids have kinetochore, chromosomes begin jerky movements.
Term
Metaphase
Definition
Centrosomes are at opposites ends. Chromosomes are on metaphase plate, centromeres aligned.
Term
Anaphase
Definition
Centromeres separate, sister chromatids separate, now a chromosome. Moves towards opposites ends of the cell. Poles of the cell move farther apart.
Term
Telophase
Definition
Cell elongates, mitosis complete, cytokinesis occurs, daughter nuclei formed.
Term
Binary Fission
Definition
Used by prokaryotic cells. Cell elongates, divides, two are identical, etc.
Term
G2 and M checkpoints
Definition
G2: Triggers mitosis.
M: Controls onset of anaphase.
Term
Cdk and Cyclin
Definition
Cdk: cyclin dependent kinases, drive the cell cycle, often in inactive form.
Cyclin: Cyclinically fluctuating concentration in the cell.
Term
How MPF relates to cdk and cyclin
Definition
MPF initiates a process that destroys it's cyclin. Cdk persists in the cell in it's inactive form until associates with new cyclin.
Term
How growth factors can influence a cell and the cell cycle
Definition
Growth factors are proteins that stimulate other cells to divide. When cell pop. reaches certain density, insufficient amount of growth factors for continued cell growth.
Term
Benign/Malignant tumor
Definition
Benign: Abnormal cells remain at original site.
Malignant: Invasive enough to impair functions of one or more organs.
Term
Metastasis
Definition
Spread of cancer cells beyond their original site. Treatment of it is harmful to actively dividing cells.
Term
Plasmodesma
Definition
Cell walls of plants are perforated with these channels. Cytoplasm passes through it and connects the living contents of adjacent cells. Unifies most of the plant into one living continuum.
Term
Tight junctions
Definition
Form continuus belts around the cell. Forms a seal that prevents leakage.
Term
Gap junctions
Definition
Provide cytoplasmic channels between adjacent cells. Special mem. prots. surround each pore so salts, amino acids, and other small molecules can pass through
Term
Desmosomes (aka communication junctions)
Definition
Functions like rivets. Fastening cells together strong. Filaments made of keratin reinforce it.
Term
Exocytosis
Definition
Cell secretes macromols. by fusion of vesicles with plasma membrane. Secretory cells use them to export their products.
Term
Endocytosis
Definition
Cell takes in macromols. and particulate matter by forming new visicles from the plasma membrane.
Term
Phagocytosis
Definition
Type of endocytosis. Cell engulfs a particle by wrapping around it and packaging it. Particle is digested after the vacuole fuses with alysosome.
Term
Pinocytosis
Definition
Type of endocytosis. Cell "gulps" droplets of extracellular fluid in tiny vesicles. Any solutes dissolved in the droplets are taken in the cell too. Unspecified in the substances it transports.
Term
Na+/K+ Pump
Definition
Pumps out 3 Na for every 2 K. With each pump crank, one positive charge is transferred from cytoplasm to extracellular fluid.
Term
Endosymbiotic theory
Definition
Hypothesis about origin of euk. cell (with the mitochondria thing.)
Term
Bulk Flow
Definition
Movement of water due to a difference in pressure between two locations.
Term
Turgor pressure
Definition
The force directed against a cell wall after intake of water and swelling of a walled cell due to osmosis.
Term
Viruses
Definition
Not a cell. A virus has some info (DNA/RNA) which allows it to make copies of itself. Must be inside a living cell before the info can be used
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