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AP Bio
Chapter 8 Reading Guide
26
Biology
11th Grade
09/29/2008

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Term
Anabolic pathways consume energy to build complicated molecules, and catabolic release energy.
Definition
Contrast the catabolic and anabolic pathways.
Term
Energy
Definition
capacity to cause change
Term
Kinetic energy
Definition
associated with relative motion of objects
Term
Heat/thermal energy
Definition
kinetic energy associated with random movement of atoms or molecules
Term
Chemical energy
Definition
potential energy available for release in a chemical reaction
Term
Thermodynamics
Definition
study of energy transformations that occur in a collection of matter
Term
First Law of Thermodynamics
Definition
energy can be transferred and transformed, but it cannot be created or destroyed
Term
Second Law of Thermodynamics
Definition
every energy transfer/transformation increases the disorder of the universe
Term
Free Energy
Definition
measures the portion of a system's energy that can perform work when the temperature is right
Term
Exergonic reactions release free energy, while endergonic reactions absorb free energy
Definition
Contrast exergonic and endergonic reactions in terms of: free energy, stability, capacity to do work
Term
No; they are at a minimum of G
Definition
Can a closed system at equilibrium do work? Why or why not?
Term
(a) Mechanical- ATP phosphorylates motor proteins
(b) Transport- phosphorylation of transport proteins
(c) Chemical- ATP phosphorylates key reactants
Definition
List and give an example of the three main kinds of cellular work done by ATP.
Term
Phosphorylated
Definition
a cell that can couple the energy of ATP hydrolysis directly to endergonic processes by transferring a phosphate group from ATP to some other molecule, such as the reactant
Term
Energy coupling uses an exergonic process to drive an endergonic one. If the change in G of an endergonic reaction is less than the amount of energy released by ATP hydrolysis, then the 2 reactions can be coupled so that, overall, the coupled reactions are exergonic.
Definition
In your own words, explain the concept of coupled reactions and ATP doing work
Term
The key to coupling exergonic and endergonic reactions is the use and regeneration of ATP
Definition
What is the relationship between exergonic reactions, endergonic reactions, and the use and regeneration of ATP?
Term
Activation energy
Definition
the amount of energy needed to push the reactants over an energy barrier, or hill, so that the "downhill" part of the reaction can begin
Term
Substrate
Definition
the reactant an enzyme acts on
Term
Enzyme substrate complex
Definition
complex in which the enzyme binds to its substrate (or substrates, when there are 2 or more reactants)
Term
Active site
Definition
a restricted region of the enzyme molecule that actually binds to the substrate
Term
Induced fit
Definition
brings chemical groups of the active site into positions that enhance their ability to catalyze the chemical reaction
Term
Up to a point, the rate of an enzymatic reaction increases with increasing temperature. Enzymes are most active within the range of pH 6-8
Definition
How do temperature and pH affect enzyme activity?
Term
Competitive inhibitors
Definition
directly compete with substrate to bind to the enzyme at the active site
Term
Noncompetitive inhibitors
Definition
impede enzymatic reactions by binding to another part of the enzyme
Term
Allosteric regulation
Definition
any case in which a protein's function at one site is affected by the binding of a regulatory molecule to a separate site
Term
Cooperativity
Definition
a mechanism that amplifies the response of enzymes to substrates
Term
Feedback inhibition
Definition
a metabolic pathway is switched off by the inhibitory binding of its end product to an enzyme that acts early in the pathway
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