Term
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Definition
HSV (herpes simplex virus) and varicella-zoster are members of the herpes virus group
vaccinations
HSV: genitalia, mouth and face
VZV:painful, chicken pox or shingles. |
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Term
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Definition
1st line for most herpes
active only for herpes
suppress DNA synthesis
no serious side effects, topical oral or IV |
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Term
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Definition
most common liver disorder
ABCDE and G
all cause acute hepatitis but only bc&d cause chronic (monitor LFT & viral load)
Hep C is leading cause of transplant |
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Term
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Definition
from blood transmitting
slow progression, liver failure, cancer and death
most effective treatment is pegylated interferon alfa combo with riboflavin
no hep c vaccine
6 genotypes but mostly type 1 (least responsive to treatment) |
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Term
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Definition
Sub Q
multi effects on viral replication cycle:
binding to receptors on the host cell, blocks viral entry into the cells, synthesis of viral messenger rna and viral proteins and viral assembly and release. |
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Term
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Definition
conventional - short half-life, must be administered frequently, 3xweek
long acting- long half life, weekly admin, pegylations: conjugating a conventional interferon with a polyethylene glycol (which serves to delay elimination) |
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Term
| adverse effects of interferon alfa |
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Definition
flu-like
neuropsychiatric (depression, SI)
thyroid dysfunction
heart damage
bone marrow suppression |
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Term
| effects of hep c treatment |
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Definition
produces a normalization of serum ALT
reduces serum hcv rna
adverse: hemolytic anemia and preg cat x |
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Term
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Definition
Influenza a- 96% of cases
b- 4%
spread via droplets
vaccine protection takes 1-2 weeks
~6 mos protection
Adverse: transient effects, flu like, guilain-barre, bell's palsy |
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Term
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Definition
| hast wo genese from pig flu, one from avian, one from human = quadruple reassortant virus |
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Term
Acute Respiratory Infection (ARI)
& Influenza like illness (ILI) |
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Definition
ARI: two or more- fever,cough, sore throat and rhinorrhea
ILI: fever and cough or sore throat |
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Term
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Definition
pts who initially present with severe illness or who's condition deteriorates begin immediately w/o labs
pts at risk for serious disease including underlying medical conditions asap after onset without labs |
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Term
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Definition
most common bac STD
adults: azithromycin 1x, doxycycline 100mg BIDx7
preg: erythromycin 500mg QIDx7 or azithromycin TIDx7
infants risk for conjunctivitis and pneumonia: e-mycin 12.5/kg QIDx14 and topical drops
preadolescent childrens suspect abuse |
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Term
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Definition
| treatment with cipro, levanox, or ceftriaxone |
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Term
| Pelvic Inflammatory Disease |
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Definition
infertility
abdominal pain, vaginal discharge and fever
caused by gonorrhea or trachomatis or both
broad spec needed
hospitalized need cefoxitin 2g IV Q6h and Doxy 100mg IV Q12h x 14days |
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Term
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Definition
spirochete treponema pallidum
Primary: enters by mouth vag or urethra. Primary lesion called a chancre sore
2nd: 2-6 wks: skin lesions and ili, enlarged lymoh nodes and joint pain
3rd: 5-40 years: changes to any organs
treat with Pen G 2.4 million units IM once |
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Term
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Definition
most commonly gardnerella vaginalis
fishy odor and secreations and pH > 4.5
oral or intravaginal metronidazole or clindamycin |
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