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INFECTION/INFLAMMATION: destroys or prevents replication of viruses, by blocking a polymerase enzyme needed to make new genomes. Decreases viral load enough so that the host immune system can fight it more effectively |
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INFECTION/INFLAMMATION: treat fungal infections |
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INFECTION/INFLAMMATION: Reduce fever, inflammation, and pain |
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INFECTION/INFLAMMATION: Treat rheumatic conditions of gout and arthritis |
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IMMUNE/CANCER: toxoids or vaccines that target a specific infectious microorganism |
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Non-specific immune responses mediated primarily by T cells and other immune cells (monocytes, macrophages, neutrophils). |
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Specific immune responses in the form of antigen-specific antibodies produced by B lymphocytes. |
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A foreign substance, usually a protein, that causes the formation of an antibody. |
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Smallest known class of microorganisms; viruses can only replicate inside host cell. |
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Viruses that cause an acute viral infection of the respiratory tract. 3 types: A, B, C...meds only available for A and B. |
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Tx-herpes viruses: HSV-1, HSV-2, herpes zoster and chicken pox; SE-GI, headache, transient burning when applied topically. Encourage fluids, oral with food, use large veins IV route, monitor liver/renal function |
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Tx- respiratory syncytial virus (RSV); SE-rash, conjunctivitis, anemia, mild bronchospasm; Teratogenic potential; Encourage fluids, oral with food, use large veins IV route, monitor liver/renal function |
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Tx-Influenza A; SE-anticholinergic effects, GI, orthostatic hypotension, lightheadedness; not used in children <12 months, those w/eczema, or lactating women; Encourage fluids, oral with food, use large veins IV route, monitor liver/renal function |
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Tx-influenza A and B; SE-GI, sinusitis; Encourage fluids, oral with food, use large veins IV route, monitor liver/renal function |
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Tx-CMV (cytomegalovirus), common in immunosuppressed individuals; SE-renal function; Encourage fluids, oral with food, use large veins IV route, monitor liver/renal function |
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Definition
Bind to sterols in cell membranes of fungi, altering cellular metabolism, leading to cell death. |
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Polyene, Broad-spectrum; Tx-serious systemic infections; SE-horrible chills, fever, nephrotoxicity, neurotoxicity, extreme irritation to veins, cardiac dysrhythymia, potassium loss; use with antihistamines, antipyretics, antiemetics, |
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Definition
Polyene; Tx-candidal diaper rash, vaginal candidiasis; SE-GI, rash, hives; administered orally, topically; yellow in color |
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Ketoconazole, fluconazole |
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Definition
Fungistatic or fungicidal, based on concentration levels; fluconazole crosses B.B. barrier; Tx-ketoconazole (dermatophytes), fluconazole (cryptococcal meningitis, candida infections); SE-headache, GI, bone marrow suppression, hepatic/renal, |
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Definition
Response to injury or infectious agent, generally localized in nature. |
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NSAIDS (nonsteroidal antiinflammatory drugs) |
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Definition
Large & chemically diverse group of drugs that possess analgesic, antiinflammatory, antirheumatic, and antipyretic activity. SE-allergic reaction, GI, hematologic, hepatic/renal function decrease, tinnitus, |
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Antigout; reduces inflammation r/t deposits of gout crystals; Tx-acute gout attacks; SE-leukopenia, bleeding in GI or Urinary tract, GI issues; take on empty stomach |
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Definition
Antigout; inhibits uric acid production; SE-agranulocytosis, aplastic anemia, potentially fatal skin conditions; take with meals |
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Uricosic, increases excretion of excess uric acid; SE- GI; |
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Uricosic, increases excretion of excess uric acid; SE- ulcerogenic, bone marrow suppression |
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Disease-modifying antirheumatic drugs (DMARDs) |
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Definition
Medications used in treatment of rheumatic diseases that have the potential to arrest or slow the actual disease process. They exhibit antiinflammatory, antiarthritic, and immunomodulating effects, which work by inhibiting movement of cells (neutrophils, monocytes, & macrophages) into an inflamed, or damaged area. |
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Any of several disorders characterized by inflammation, degeneration, or metabolic derangement of connective tissue structures. |
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A chronic autoimmune disorder that commonly causes inflammation and tissue damage in joints. |
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