Term
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Definition
live attenuated varicella vaccine, can be used for post-exposure prophylaxis, one injection for children under 12, two injections for people over 13 |
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Definition
live attenuated varicella vaccine, for prevention of zoster in those over 60 years |
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Definition
guanine analogue that requires viral thymidine kinase for activation, treatment for VZV, HSV |
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Term
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Definition
treatment of herpes simplex keratoconjunctivitis, neurotoxicity, requires large volumes of fluid for administration, bone marrow suppression |
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Term
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Definition
orally bioavailable drug with same action as guanine analogues, treatment for VZV and HSV |
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Term
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Definition
prodrug of penciclovir with similar action as guanine analogues, oral formulation, approved treatment for zoster only |
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Definition
structurally similar to guanine analogues, competitively inhibits deoxyguanosine triphosphate into DNA by viral DNA polymerase, for treatment of CMV |
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Term
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Definition
prodrug of Ganciclovir, used for long term treatment of CMV |
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Term
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Definition
inorganic pyrophosphate analogues, inhibits DNA polymerase by blocking pyrophosphate binding site, only available in IV formulation, high renal toxicity, chelates divalent metal ions, active against CMV, HSV, influenza, HBV, HIV |
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Term
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Definition
cytosine analogue, significant renal toxicity, very long half life, used to treat resistant CMV |
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Term
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Definition
live attenuated vaccine for healthy, non-pregnant persons from 2 to 49 for the prevention of influenza, contains 2 A strains and one B strain |
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Term
Injected influenza vaccine |
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Definition
treatment inactivated vaccine for anyone over 6 months old for prevention of influenza, contains 2 A strains and one B strain |
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Term
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Definition
active against influenza A, inhibits M2 protein and inhibits viral membrane fusion |
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Term
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Definition
inhibits neuraminidase of influenza A and B, an inhaled therapy |
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Term
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Definition
inhibits neuraminidase of influenza A and B, an oral therapy that may cause psychiatric problems |
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Term
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Definition
HPV4 vaccine that protects against cervical cancer and genital warts, recommended for girls and boys |
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Term
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Definition
HPV2 vaccine that protects against cervical cancer but not genital warts, recommended for girls and young women |
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Term
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Definition
HAV vaccine, for travelers and post exposure prophylaxis, administered in 2 doses |
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Term
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Definition
HBV vaccine, for everyone, administered in 3 doses |
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Term
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Definition
increases natural killer and cytotoxic T cell activity, three injections a week for 6-12 months, given as treatment for HBV, can cause psych symptoms and flu like symptoms |
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Term
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Definition
nucleoside analogue that competitively inhibits reverse transcriptase, used for HBV and HIV infection |
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Term
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Definition
nucleotide analogue that inhibits HBV reverse transcriptase |
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Term
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Definition
nucleoside analogue that is good for resistant HBV strains, may cause dizziness, headache, lethargy, GI symptoms and photosensitivity |
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Term
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Definition
thymidine nucleoside analogue for HBV treatment, may cause elevated CPK and muscle weakness |
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Term
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Definition
nucleotide to treat HBV that may cause HIV resistance in coinfected patients |
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Term
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Definition
for treatment of hepatitis C in combination with pegylated interferon alpha, but may cause hemolytic anemia and abnormal fetal development |
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Term
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Definition
increases natural killer and cytotoxic T cell activity, one injection a week for 6-12 months, given as treatment for HBV, can cause psych symptoms and flu like symptoms |
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Term
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Definition
NS3/4A protease inhibitor for HCV, may cause skin rash |
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Term
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Definition
NS3/4A protease inhibitor for HCV, may cause anemia |
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Term
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Definition
nucleoside reverse transcriptase inhibitor. Side effects include peripheral neuropathy |
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Term
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Definition
nucleoside reverse transcriptase inhibitor. Potentially fatal hypersensitivity reaction with HLAB5701 |
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Term
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Definition
non-nucleoside reverse transcriptase inhibitor that causes severe hepatotoxicity |
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Term
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Definition
non-nucleoside reverse transcriptase inhibitor that causes psychiatric symptoms and is teratogenic |
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Term
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Definition
HIV protease inhibitor, combination lopinavir and ritonavir, side effects include nausea, vomiting, diarrhea |
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Term
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Definition
HIV protease inhibitor, causes asymptomatic hyperbilirubinemia |
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Term
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Definition
HIV protease inhibitor, causes severe hepatitis |
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Term
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Definition
HIV protease inhibitor, can cause rash |
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Definition
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Term
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Definition
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Term
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Definition
inhibits HIV1 integrase, side effects include diarrhea, nausea and fatigue |
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Term
Nucleoside reverse transcriptase inhibitors |
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Definition
Class of drugs associated with potentially fatal lactic acidosis with hepatic steatosis, inhibits HIV via early chain termination |
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Term
Non-nucleoside reverse transcriptase inhibitors |
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Definition
Class of drugs associated with rash and CYP affects, noncompetitive inhibitors of reverse transcriptase |
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Term
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Definition
Class of drugs associated with GI symptoms, lipodystrophy, hepatotoxicity, and inhibits CYP3A |
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Term
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Definition
Class of drugs that block chemokine receptors on immune cells |
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