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antipsychotics
antipsychotics
7
Pharmacology
Professional
11/01/2012

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Cards

Term
positive symptoms
Definition
hallucinations, delusions, bizarre behavior, thought disorders
Term
negative symptoms
Definition
blunted emotion, poor self care, social withdrawal, poverty in speech
Term
major receptors antagonized
Definition
Dopamine
D1-like receptors (D1 and D5)
D2-like receptors (D2, D3, D4)
Term
newer agents antagonize..
Definition
serotonin (5-HT)
Term
minor receptors antagonized
Definition
norepinephrine-A1 receptor blockade:hypotension, sedation; A2 receptor blockade: may be helpful in therapy
acetylcholine: anticholingergic effects (clozapine, thioridazine)
histamine- H1 receptor antagonists: sedation, weight gain
Term
5HT2A receptor antagonists
Definition
clozapine, olanzapine, risperidone
Term
older serotonin antagonist agents
Definition
chlorpromazine, haldol, thioriadazine
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