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Antipsychotics Depression Psychotics
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84
Pharmacology
Undergraduate 4
11/03/2010

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Term
Medulla
Definition
Vegetative Functions
Term
Cerebellum
Definition
Smooth Muscle Movement, Coordination
Term
Midbrain
Definition
Contains cells that produce neurotransmitters
Term
Substantia Nigra
Definition
Produces Dopamine, death causes parkinson's, releases on Basal Ganglia
Term
VTA
Definition
produces dopamine onto limbic area
Term
Basal Ganglia
Definition
Voluntary Movement
Term
Limbic System
Definition
Emotion, Thought, Learning, Memory
Term
Limbic System
Definition
Emotion, Thought, Learning, Memory
Term
Prefrontal Cortex
Definition
Planning, Moivation
Term
Thalmus
Definition
Relay for senses
Term
Hypothalmus
Definition
Endocrine, Sex, Feeding
Term
Adderall
Definition
Anti-psychotic, ADHD, mixture of amphetamine salts
Term
Ritallin
Definition
Anti-psychotic, ADHD, DAT blocker
Term
Stratera
Definition
Anti-psychotic, ADHD, NET inhibitor
Term
Stratera
Definition
Anti-psychotic, ADHD, NET inhibitor
Term
Provigil
Definition
Anti-psychotic, ADHD, DAT/NET weak inhibitor
Term
Nuvigil
Definition
Anti-psychotic, ADHD, Cheaper because only active isoform
Term
Vyvanse
Definition
Anti-psychotic, ADHD, Lysine prodrug to prevent abuse
Term
Intuniv
Definition
Anti-psychotic, ADHD, a2 agonist, used when others are intolerated
Term
Phenteramine
Definition
Anti-psychotic, anorexic, Act like amphetamine
Term
Benzphetamine
Definition
Anti-psychotic, anorexic, Act like amphetamine
Term
Phenphetamine
Definition
Anti-psychotic, anorexic, Act like amphetamine
Term
Phenylpropanolamine
Definition
Anti-psychotic, anorexic, effective, increase in stroke
Term
Meridia
Definition
Anti-psychotic, anorexic, NET/DAT inhibitor, prodrug, not effective
Term
Parkinson's Cause
Definition
Caused by death of substantia negra
Term
Parkinson's Symptoms
Definition
Symptoms of tremors and lack of controlled movement
Term
Sinemet
Definition
L-DOPA + Carbadopa
Term
Carbadopa
Definition
Taken with L-DOPA to act peripherally as a decarboxylase inhibitor
Term
Apomorphine
Definition
Dopamine Agonist, Parkinson's, D1/D2 nonselective, non-oral
Term
Mirapinol
Definition
Parkinson's, D2 agonist
Term
Rapinoral
Definition
Parkinson's D2 agonist, restless leg syndrome
Term
Bromocriptine
Definition
Parkinson's D2 agonist, Hyperprolactemia
Term
Sellegiline
Definition
Parkinson's MAOI
Term
Rasegilline
Definition
Parkinson's MAOI
Term
Entacapone
Definition
Parkinson's COMT inhibitor
Term
Benztropine
Definition
Parkinson's Antimuscarinic
Term
Procyclidine
Definition
Parkinson's antimuscarinic
Term
Psychadelics
Definition
5HT2A agonists, cause hallucinations, have tachyphillaxis
Term
Mescaline
Definition
Pyscadelic phenylethylamine, ceremonial
Term
Psicybin
Definition
Pyscadelic Tryptamine, Shrooms
Term
DMT
Definition
Pyscadelic Tryptamine, ceremonial, can be combined with MAOI to increase effect
Term
STP/DOM
Definition
Pyscadelic phenylethylamine
Term
DOI
Definition
Pyscadelic phenylethylamine, used for research purposes
Term
LSD
Definition
Pyscadelic ergoline, most potent hallucinogen, diethylamine makes it potent
Term
MDMA/Extacy
Definition
Entactogenic Psychedelic, can cause serotonin syndrome
Term
Serotonin Syndrome
Definition
Hyperthermia that can be fatal following extacy
Term
THC
Definition
CB1/2 Agonist, CB most prevalent receptor in brain, GPCR-Gi coupled
Term
PCP/Ketonine
Definition
Dissociative psychedelic, NMDA antagonist
Term
Schizophrenia Treatment
Definition
Treatment w/ D2 antagonists
Term
D2 Antagonist Symptoms
Definition
Positive Symptoms, EPS
Term
5HT2A Antagonist Symptoms
Definition
Negative Symptoms, weight gain, diabetes
Term
Tardative Dyskenisia
Definition
Irreversible EPS
Term
Malignant Neuroleptic Syndrome
Definition
symptoms of EPS, fatal, treat with diazepame
Term
Chloropromazine
Definition
First Typical Schiz drug
Term
Haloperidol
Definition
Typical Schiz drug with high EPS
Term
Fluphenazine
Definition
Typical Schiz drug
Term
Thiothixine
Definition
Typical Schiz
Term
Droperidol
Definition
Non-schiz typical used to treat nausea and vomiting
Term
Pimizide
Definition
Non-schiz typical to treat Tourrette's
Term
Clozapine
Definition
Atypical Schiz causing agranulocytosis
Term
Olanzapine
Definition
Atypical Schiz, bioisostere of clozapine, increased diabetes
Term
Risperidone
Definition
Atypical Schiz, actually designed to antagonize 5HT2A and D2
Term
Ziprazidone
Definition
Atypical Schiz prolongs QT interval
Term
Aripiprazole
Definition
Atypical Schiz, partial D2/5HT2A agonist, also used for depression
Term
Anti-depressants Action
Definition
Act as transport inhibitors
Term
Phenelzine
Definition
Anti-Depressant,Irreversible MAOI-A/B Inhibitor
Term
Tranylcypromine
Definition
Anti-Depressant,Irreversible MAOI-A/B Inhibitor
Term
Selegeline
Definition
Anti-Depressant,Irreversible MAOI-A/B Inhibitor
Term
Moclobemide
Definition
Anti-Depressant,Reversible MAOI-A Inhibitor
Term
Imipramine/ Desipramine
Definition
TCA's- NET/SERT inhibitors
Term
Amitriptyline/ Nortrytyline
Definition
TCA's- NET/SERT inhibitor
Term
Doxapine, Trimipramine, Clonipramine
Definition
TCA's- last causing orgasm when yawning
Term
SSRI action
Definition
acts by blocking SERT
Term
Fluoxitine, Fluvoxitine, Paroxitine, Sertraline, Citalopram
Definition
SSRI's
Term
Trazadone
Definition
5HT2A selective antagonist for depression
Term
Mirtazapine
Definition
5HT2A and a2 antagonist, least sexual side effects
Term
Brupropion(Wellbutrin)
Definition
Blocks all transporters but DAT selective to treat depression and smoking cessation
Term
Dual Inhibitors(SNRI's) action
Definition
Block NET and SERT
Term
Duloxetine, Veslatoxine
Definition
NSRI's (dual)
Term
NET inhibitors (NSRI's)
Definition
Net Inhibitors to treat depression
Term
Atomoxetine, Reloxetine
Definition
NSRI's used to treat depression and also pain
Term
Lithium
Definition
First used to treat Bi-polar, small therapeutic window
Term
Carbamazepine/Valproate
Definition
Na blockers, anti-convulsive, 1st line for bi-polar
Term
Olanzapine+Fluoxitine
Definition
Used dually in bi-polar to treat both mania and depression
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