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AntiProtozoan Drugs
Downstate > HemeOnc > AntiProtozoan Drugs
31
Medical
Graduate
11/17/2010

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Term
tx for chloroquine-resistant P. falciparum
Definition
quinine+clindamycin, quinine+doxycycline, quinine+atovaquone-proguanil
Term
tx for P. vivax or P. ovale
Definition
primaquine
Term
prophylaxis for malaria
Definition
mefloquine, chloroquine
Term
AE: hemolysis in G6P dehydrogenase deficient patients (3)
Definition
chloroquine, primaquine, quinine
Term
AE: cardiotoxicity, prolongs QT intervals
Definition
quinidine
Term
tx for multidrug resistant P. falciparum
Definition
artesunate, artemether
Term
tx for Babesiosis
Definition
quinine+clindamycin
Term
inhibits heme polymerase
Definition
chloroquine
Term
inhibits mitochondrial transport and dihydrofolate reductase
Definition
atovaquone-proguanil
Term
tx for Tb. gambiense
Definition
eflornithine
Term
inhibits ornithine decarboxylase
Definition
eflornithine
Term
tx for Tb. rhodesiense
Definition
suramin+melarsoprol
Term
prophylaxis for Tb.gambiense
Definition
suramin
Term
tx for T. cruzi
Definition
nifurtimox
Term
inhibits pyruvate kinase
Definition
melarsoprol
Term
forms reactive oxygen species
Definition
nifurtimox
Term
forms free radicals
Definition
artesunate, artemether
Term
tx. for T. gondii in pregnant women
Definition
spiramycin
Term
tx. for T. gondii in immunosuppressed pts
Definition
pyrimethamine
Term
tx. for P. carinii
Definition
TMP-SMX; primaquine+clindamycin
Term
tx for Leishmania
Definition
stibogluconate
Term
tx for Leishmania relapse
Definition
amphotericin B
Term
contraindicated for pts with renal or hepatic disease
Definition
suramin
Term
AE: cinchonism
Definition
quinine
Term
AE: tinnitus, headache, dysphoria, emesis, convulsions, coma, death
Definition
quinine
Term
AE: hypo/hyperglycemia, diabetes
Definition
pentamidine
Term
tx: T. gambiense blood stages
Definition
suramin, pentamidine
Term
AE: fever, headache, impaired speech, seizures, death, coma
Definition
melarsoprol
Term
tx for Tb. rhodesiense CNS stage
Definition
melarsoprol
Term
AE: convulsions, paresthesias, polyneuritis, vomiting, nausea, seizure, coma, death
Definition
nifurtimox
Term
contraindicated for pts with cardiac, neurological, or psychiatric disorders
Definition
mefloquine
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