are worms found primarily in the gastrointestinal tract, liver, lungs, and circulatory system

The two major groups:

Nematodes(roundworms) (ascarids,hookworms,lungworms,threadworm,whipworm, kidney worm, bladder worm, heartworm)

Platyhelminths(flatworms)

Cestodes (tapeworms)

Trematodes (lung flukes)

kill worm parasites.

• Antinematodal
• Anticestodal
• Antitrematodal

water-soluble=orally

soluble compounds= orally as solution, topically as pour-on, or via injection

treat arthropod infections (insects & arachnids)

(insects include; flies, mosquitoes,bots,cuterebra,lice, and fleas)(arachnids include; spiders, scorpians, ticks, and mites)

works against nematodes (ascarids,hookworms, lung worms, threadworms, whipworms, kidney worm, bladder worm, heartworm)

six groups of drugs:

• Benzimidazoles
• Imidazothiazoles
• Tetrahydropyrimidines
• Organophosphates
• Piperazines
• Avermectins/macrocyclic lactones

excellent against nematode infestations-taken orally-

work by interfering with energy metabolism of the worm. rare side effects; vomiting, diarrhea, & lethargy.

Thiabendazole (Tresadermotic)

Oxibendazole (Anthelcide EQ)

Mebendazole (Telmintic)

Fenbendazole (Panacur)

Albendazole (Valbazen)

Febantel/Praziquantal/pyrantel pamoate (Drontal Plus)

Oxenfendazole (Benzelmin synanthic)

thiabendazole

(Tresadermotic)

• group: benzimidazole
• antinematodal drug

works against

ascarids(roundworms) & Strongyles (threadworms)

also has antifungal (yeast)

& anti-inflammatory (earmites) effects.

Suitable for otic preperation

*REFRIDGERATE*

*PO ADMIN*

oxibendazole

 (Anthelcide EQ)

(equine wormer paste)

• group: benzimidazole
• antinematodal drug

works against Nematodes (ascarids, hookworms, lung worms, threadworms, whipworms, kidney worm, bladder worm, heartworm)

In dogs, liver toxicity noted

*PO ADMIN*

mebendazole

(Telmintic)

• group: benzimidazole
• antinematodal drug
• anticestodal drug

works against; ascarids (roungworms), hookworms, cestodes (tapeworms)

liver toxicity has been noted

*PO ADMIN*

fenbendazole

(Panacur)

• group: benzimidazole
• antinematodal drug
• anticestodal drug
• antiprotozoal drug
• antitrematodal drug

works against; nematodes (ascarids,hookworms,lung worms, threadworm, whipworm, kidney worm, bladder worm, heartworm), cestode (Taenia pisiformis), trematodes (flukes)

treats metronidazole-resistant Giardiasis

*PO ADMIN*

albendazole

(Valbazen)

• group: benzimidazole
• anticestodal drug
• antinematodal drug
• antitrematodal drug
• antiprotozoal drug

works against tapeworms(cestodes), flukes (trematode), some nematodes (ascarids, hookworms, lung worms, threadworms, whipworms, kindey worm, bladder worm, heartworm) Giardia (protozoa)

works by interfering with energy metabolism of worm.

not approved in lactating animals

*PO ADMIN*

oxenfendazole

(Benzelmin Synanthic)

febantel

praziquantal/pyrantel pamoate

(Drontal Plus)

• group: probenzimidazoles
• antinematodal drug
• anticestodal drug
• antitrematodal drug

works against; all cestodes (tapeworms), flukes (trematodes), nematodes (ascarids, hookworms, lungworms,threadworms,whipworms,kidneyworms, bladder worms, heartworms)

probiotic metabolized into true benzimidazole in animals body.

second group of antinematodal drugs.

levamisole is an example

levamisole

(Levasole)

(Tramisol)

include;

• pyrantel pamoate
• pyrantel tartrate
• morantel tartrate

these drugs are cholinergic agonists that mimic the action of acetylcholine.

This causes initial stimulation and then paralysis of the worm, allowing it to be excreted by the intestine.

somewhat pleasent tasting drug, very safe.

pyrantel pamoate

(Nemex)

(Strongid-T)

pyrantel tartrate

(Strongid- C)

morantel tartrate

(Rumatel 88)

• group: tetrahydropyrimidines
• antinematodal drug

works against; ascarids (roundworms), pinworms, strongyles (threadworms), hookworms.

cholinergic agonists that mimic the action of acetylcholine, initial stimulation then paralysis of worm.

organophosphate

(OP)

used against both endoparasites and ectoparasites.

have a narrow range of safety, generally given as a feed supplement to beef and dairy cattle.

effective against bots in horses

inhibit cholinesterase, causing acetylcholine to remain active in the neuromuscular junction of parasite.

neurotoxic to parasite and can cause neurologic side effects in the host.

*NO heartworm+ Dogs could cause dyspnea/death.

*DON'T us OP's as extra-label.

trichlorfon

(Trichlorphon)

dichlorvos

(Task)

coumaphos

(Baymix)