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Antimicrobials, Bugs and targets
This will ask you a target or a bug and give you the drugs that target it
35
Medical
Professional
02/04/2012

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Term
Drugs with significant Post Antibiotic Effect (2)
Definition
Aminoglycocides
Streptogramins
Term
Drugs with billiary excretion (5)
Definition
Nafcillin
Cefitriaxone IV
Tigecycline
Macrolides
Refampin
Term
Drugs eliminated fecally (2)
Definition
Doxycycline
Minocycline
Term
Drugs not stable to acid (3)
Definition
Pen G
Antipseudomonal Pens
Sulfonamides
Term
Drugs that target 30s (3)
Definition
Aminoglycocides
Tetracyclines
Tigecycline
Term
Drugs that target the 50s (6)
Definition
Macrolides
Telithromycin
Chloramphenicol
Streptogramins
Linezolid
Term
Drugs that commonly cause superinfections (3)
Definition
Clindamycin
3rd and 4th gen Cephalosporins
Tetracyclines
Term
Clinically important exceptions:

Cephalosporins
Aminoglycosides
Daptomycin
Sulfonamides
Ertapenam
Definition
Cephs: No LIsteria
AGs: No anaerobes
Dapto: Can't use for any pneumonia
Sulfonamides: Rickettsiaea is favored by them
Ertapenam: No activity against Pseudomonas (but better G+ coverage
Term
Drugs for MSSA (8)
Definition
Penicillinase-Resistant Pens
Cephs (all except Cefixime)
Carbapenams
Doxy/Minocycline
Tigecycline
Streptogramins
Linezolid
Fluoroquinolones (2nd gen or higher)
Term
Drugs for MRSA (7)
Definition
Ceftaroline (5th gen ceph)
Vancomycin
Doxy/Minocycline (CA only)
Tigecycline
Streptogramins (dalfopristin/quinopristin)
Linezolid
Daptomycin
Term
Drugs for VRSA and VRE (4)
Definition
Tigecycline
Streptogramins (facecium only)
Linezolid
Daptomycin
Term
Drugs for KPC+ (2)
Definition
Tigecyclin
Polymyxin E (Colistin)
Term
Drugs for ESBL (3)
Definition
Carbapenams
Fluoroquinalones (not gemi)
Polymyxins
Term
Drugs for Listeria (8)
Definition
Pen G
Pipercillin
Carbapenams
Vancomycin
Doxy/Minocycline
Clarithromycin
Sulfonamides
Fluoroquinolones (2nd gen)
Term
Drugs for enterococcus (6)
Definition
Pen G (faecalis only)
Ceftaroline (5th gen ceph)
Imipenam + Cilastatin
Vancomycin
B Lactam + AMG synergy
Flourquinolones (Faecalis only, and 2nd gen only)
Term
Drug for Saprophyticus (1)
Definition
Nirofurantoin
Term
Drugs for Neisseria (5)
Definition
Pen G (meningitidis only)
Meropenem (Meningitigis)
Azithromycin (Gonorrhaoea
Sulfonamides (Meningiitidis)
Fluoroquinolones (not Gemi)
Term
Drugs for Klebsiella (6)
Definition
Antipseudomonal Pens
Cephalosporins (all gens)
Carbapenems
Aztreonam
Polymyxins
Aminoglycocides
Term
Drugs for Pseudomonas (7)
Definition
Antipseudomonal Pens
Ceftazidime (3rd gen ceph)
4th Gen cephs
Carbapenems (not Erta)
Aztreonam
Polymyxins
Aminoglycosides
Term
Drugs for Enterobacter (5)
Definition
Antipseudomonal pens
Cephalosporins (4th gen)
Carbapenems
Aztreonam (Citrobacter)
AMinoglycocides
Term
Drugs for Indole + (5)
Definition
Antipseduomonal Pens
Cephalosporins (2-4th gen)
Carbapenems
Aztreonam
Aminoglycocides
Term
Drugs for Shigella (4)
Definition
Ampicillin
Celphalosporins (3rd and 4th gen)
Carbapenems
Aztreonam
Aminoglycocides
Term
Drugs for Legionella 3)
Definition
Macrolides (clarithromycin)
Streptogramins (reserved)
Linezolid (reserved
Term
Drugs for Boretella Pertussis (1)
Definition
Macrolides
Term
Drugss for Syphillis (1)
Definition
Pen G
Term
Drugs for H Pylori (3)
Definition
Doxy/Minocycline
Macrolides
Metronidazole
Term
Drugs for Borrelia Burgdorferi (Lymes D) (3)
Definition
Pen G
Doxy/Minocycline
Macrolides
Term
Drugs for Chlamydia (5)
Definition
Doxy/Minocycline
Macrolides
Streptogramins (reserved)
Linezolid (reserved)
Fluouroquinolones
Term
Drugs for Rickettsiae (Rocky Mt Fever) (1)
Definition
Doxy/Minocycline

Just a reminder:
DO NOT USE SULFONAMIDES
Term
Drugs for C Diff (2)
Definition
Oral Vancomycin
Metronidazole
Term
Drugs for Bacteroides (6)
Definition
Clindamycin
Metronidazole
Antipseudomonal Pens
Cephamycins (2nd gen Cephs: Cefoxitin, Cefotetan)
Carbepenems (Erta most effective)
Azitromycin
Term
Drugs to use for general anaerobes (3)
Definition
Pen G (Clostridium, Peptostreptococcus)
Tigecycline
Fluoroquinolones (clostridium)
Term
Drugs for Protozoa (3)
Definition
Clindamycin (P. carinii, Taxoplasmosis)
Sulfonamides (P. Carinii, Toxoplasmosis)
Metronidazole (Trichomonas vaginalis, entamoeba, Giardia)
Term
Drugs for Mycobacterium Avium Complex (3)
Definition
Clarithromycin
Rifabutin
Fluoroquinolones
Term
Drugs for Plasmodium Falciparum (3)
Definition
Doxycycline (NOT MINO THIS TIME)
Sulfonamides
Clindamycin
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