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Antimicrobials
List 11
17
Microbiology
Undergraduate 3
05/10/2011

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Term
chemotherapy
Definition
use of chemicals to treat various aspects of diesease
Term
chemotherapeutic agent
Definition
Drug, any chemical used in medicinal practice. one kind of anti microbial agent used to treat disease caused by microbes
Term
antibiotics
Definition
chemical substance produced by micro-organism that can inhibit the growth or destroy organisms
Term
synthetic drugs
Definition
agents synthesized in a lab
Term
semisynthetic drugs
Definition
antimicrobial agent made partly by laboratory synthesis and micro organism
Term
selective toxicity
Definition
ability of an antimicrobial agent to harm microbes without causing significant damage to the host
Term
toxic dosage level
Definition
amount of drug necessary to cause host damage
Term
therapeutic dosage level
Definition
level of drug dosage that successfuly eliminates pathogenic organims if maintained over a period of time
Term
spectrum of activity
Definition
range of microbes against which the agent will work
Term
broad spectrum
Definition
wide range includes more than one kind of organism
Term
narrow spectrum
Definition
small # of species single taxon group
Term
mode of action
Definition

inhibition of cell wall synthesis

disruption of cell membrane function

inhibition of protein synthesis

inhibition of nucleic acid synthesis

action as antimetabolites

Term
super infection
Definition
an invasion of replacement micro flora after an antibiotic
Term
resistance
Definition
ability of a micro organism to remain unharmed by a antimicrobial agent
Term
evasion
Definition
micro organism stay in tissues that the anti-biotics cannot reach
Term
chromosomal resistance
Definition
drug resistance of microorganism due to mutation in chromosomal DNA
Term
extrachromosomal resistance
Definition
drug resistance of microorganism due to the prescence of resistance R plasmids
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