Term
|
Definition
|
|
Term
WHERE IS EZETIMIBE ABOSRBED AND EXCRETED AT? |
|
Definition
IN THE GI TRACT AND EXCRETED MOSTLY UNCHANGED IN THE FECES |
|
|
Term
|
Definition
BINDS TO CHOLESTEROL TO DECREASE ABSORPTION. INHIBITS THE ABSORPTION OF BILIARY AND DIETARY CHOLESTEROL IN THE SMALL INTESTINE. |
|
|
Term
A COMBINATION OF EZETIMIBE AND SIMVASTATIN FORM WHAT DRUG? |
|
Definition
|
|
Term
WHAT ARE 2 SIDE EFFECTS OF EZETIMIBE? |
|
Definition
|
|
Term
HOW DOES OMEGA-3 FATTY ACIDS WORK? |
|
Definition
DECREASE TRIGLYCERIDES BY NUCLEAR TRANSCRIPTION REGULATION, SIMILAR TO FIBRATES. |
|
|
Term
|
Definition
BIND TO AND ACTIVATE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR A (PPARA). CHANGES LIPID METABOLISM TO DECREASE PLASMA TRIGLYCERIDS LEVELS AND INCREASE HDL LEVELS. |
|
|
Term
WHAT ENZYME DOES FIBRATES INCREASE? |
|
Definition
LIPOPROTEIN LIPASE, WHICH CATALYZES AND HYDROLYZES THE REMOVAL OF TRIGLYCERIDES FROM VLDL. |
|
|
Term
DOES FIBRATES HAVE AN ANTI-INFLAMMATORY EFFECT? |
|
Definition
YES, IT REDUCES THE RISK OF PLAQUE RUPTURE (LIKE STATINS). |
|
|
Term
WHERE IS FIBRATES EXCRETED AT? |
|
Definition
|
|
Term
WHAT ARE 3 SIDE EFFECTS OF FIBRATES? |
|
Definition
GI UPSET, MYOPATHY, AND IT MAY ELEVATE LFTS |
|
|
Term
WHAT DRUG INTERACTIONS CAN FIBRATES CAUSE? |
|
Definition
MAY DISPLACE WARFARIN FROM ALBUMIN |
|
|
Term
|
Definition
GEMFIBROZIL (LOPID) AND FENOFIBRATE (TRICOR) |
|
|
Term
WHAT IS NIACIN ALSO KNOWN AS? |
|
Definition
NICOTINIC ACID OR VITAMIN B3 |
|
|
Term
|
Definition
LOWERS LDL AND TRIGLYCERIDE LEVLES AND INCREASE HDL LEVELS. INHIBITS THE FORMATION OF HEPATIC VLDL AND LIPOLYSIS. |
|
|
Term
WHERE IS NIACIN ABOSRBED AT? |
|
Definition
|
|
Term
WHAT IS NIACIN METABOLIZED AND EXCRETED AT? |
|
Definition
|
|
Term
WHAT 2 MEDIATIONS WILL DECREASE THE SIDE EFFECTS OF NIACIN? |
|
Definition
|
|
Term
WHAT ARE 7 SIDE EFFECTS OF NIACIN? |
|
Definition
FLUSHING, PRUITIS, ELEVATED LFTS OR HEPATITIS, GI UPSET, PUD, DECREASES INSULIN SENSITIVITY, AND POTENTIATE STAIN-INDUCED MYALGIAS. |
|
|