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Antihyperlipidemic Drugs
Part 1
28
Nursing
Graduate
11/02/2014

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Cards

Term
WHAT 3 MAIN THINGS IS LIPIDS NECESARY FOR?
Definition
CELL MEMBRANE FORMATION AND MAINTENANCE; HORMONE PRODUCTION; STERIOD PRODUCTION
Term
_____ AND _____ ARE POORLY SOLUBLE IN THE BLOOD, SO THEY MUST BE TRANSPORTED VIA _____.
Definition
CHOLESTEROL AND TRIGLYCERIDES; LIPOPROTEINS
Term
WHAT IS COMPOSED OF 3 FATTY ACIDS AND GLYCEROL.
Definition
TRIGLYCERIDES
Term
WHAT SERVES AS A RESERVOIR FOR FUEL USED IN ATP GENERATION?
Definition
TRIGLYCERIDES
Term
WHAT IS THE TERM FOR HIGH LIPID LEVELS?
Definition
HYPERLIPIDEMIA
Term
WHAT CAN HIGH TRIGLYCERIDE LEVELS RESULT INTO?
Definition
PANCREATITIS
Term
WHICH LIPID LEVEL DOES ACITIVTY CHANGE?
Definition
HDL
Term
ARE MALES OR FEMALES MORE PRONE TO CAD?
Definition
MALES
Term
WHAT IS THE EFFECT OF ESTROGEN?
Definition
CAN INCREAES COAGULABILITY BUT DECREASES LIPID LEVELS (ISSUE WITH HORMONE REPLACEMENT OR BCP'S IS CLOTS...NOT LIPID LEVELS)/
Term
NAME 4 LIPOPROTEINS.
Definition
CHYLOMICRONS, VERY LOW DENSITY LIPOPROTEINS (VLDL), LOW DENSITY LIPOPROTEINS (LDL), HIGH DENSITY LIPOPROTEINS (HDL).
Term
WHERE ARE CHYLOMICRONS FORMED AT?
Definition
IN THE INTESTINES (EXOGENOIUS PATHWAY)
Term
WHAT 4 THINGS MAKES UP CHYLOMICRONS?
Definition
DIETARY CHOLESTEROL, TRIGLYCERIDES, BILE ACIDS, AND PROTEINS
Term
WHAT DOES CHYLOMICRONS DO?
Definition
TRANSPORT LIPIDS FROM THE GUT TO ADIPOSE TISSUE AND LIVER.
Term
WHERE ARE VERY LOW DENSITY LIPOPROTEINS (VLDL) FORMED?
Definition
IN THE LIVER (ENDOGENOUS PATHWAY)
Term
WHAT DOES THE BODY DO TO FREE FATTY ACIDS DURING FASTING?
Definition
THE BODY INCREASES THE DELIVERY TO THE LIVER.
Term
WHAT 2 THINGS STIMULATE TRIGLYCERIDE PRODUCTION IN THE LIVER?
Definition
INCREASED CARBS AND SATURATED FATS FROM THE DIET.
Term
WHAT DOES VLDL DO?
Definition
TRANSPORT TRIGLYCERIDES THAT ARE SYNTHESIZED ENDOGENOUSLY.
Term
WHAT DOES LDL DO?
Definition
THEY TRANSPORT CHOLESTEROL TO PERIPHERAL TISSUED TO BE USED IN CELL MEMBRANES AND STEROIDS. THESE ARE BAD CHOLESTEROL.
Term
WHAT ARE THE SMALLEST LIPOPROTEINS WITH THE LOWEST LIPID CONTENT AND HIGHEST PROTEIN?
Definition
HDL
Term
WHAT TYPE OF LIPOPROTEIN HAS EXHIBITS ANTIATHEROGENIC EFFECTS?
Definition
HDL
Term
WHEN IS HDL ELEVATED? 4 ANSWERS
Definition
AEROBIC ACTIVITY, ALCOHOL USE, ESTROGEN USE, CORTICOSTEROID THERAPY.
Term
WHAT DOES HDL DO?
Definition
TRANSPORTS CHOLESTEROL FROM ATHEROSCLEROTIC PLAQUES AND PERIPHERAL TISSUE TO THE LIVER... THIS IS CALLED REVERSE CHOLESTEROL TRANSPORT.
Term
WHERE IS LIPOPROTEIN(A) FOUND? WHAT TYPE OF GENETIC INFLUENCE DOES IT HAVE?
Definition
IN ATHEROSCLEROTIC PLAQUES. LARGE GENETIC INFLUENCES.
Term
LIPOPROTEINS THAT CARRY APOLIPOPROTEIN B-100 PRIMARY FUNCTION IS WHAT?
Definition
TO DELIVER TRIGLYCERIDES TO MUSCLE TISSUE FOR ATP AND TO ADIPOSE TISSUE FOR STORAGE. ALSO TRANSPORT LIPIDS INTO THE ARTERY WALL.
Term
WHAT 4 THINGS ARE PLAQUES FORMED BY?
Definition
COLLAGEN, FIBRIN, CALCIUM, AND FOAM CELLS.
Term
WHAT ARE FOAM CELLS?
Definition
MACROPHAGES AND SMOOTH MUSCLE CELLS THAT CONTAIN CHOLESTEROL
Term
WHAT CAN UNDERGO APOPTOSIS OR OTHER FORMS OF CELL DEATH AND RELEASE FREE RADICLES AND ENZYMES?
Definition
PLAQUE
Term
THE RELEASE OF FREE RADICALS AND ENZYMES CAUSE WHAT 2 THINGS?
Definition
INCREASE INFLAMMATION IN THE VASCULAR ENDOTHELIUM AND EXCESSIVE CELL DEATH CAN CAUSE PLAQUE RUPTURE.
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