Term
|
Definition
| stabilize mast cell membrane and prevent degranulation |
|
|
Term
| diphenhydramine (benadryl) |
|
Definition
1st gen H1 Antagonist
Use - hay fever, urticaria, motion sick
adr- VERY SEDATING |
|
|
Term
|
Definition
1st gen H1 antagonist
use: motion sickness |
|
|
Term
| H1 first gen v second gen |
|
Definition
1st gen have H2 and muscarinic SE's
1st gen cross BBB and cause sedation and anticholinergic activity ( inhibit learning) |
|
|
Term
Dimenhydrinate
Diphenhydramine
Chlorpheniramine
Doxylamine
Hydroxyzine
Cyclizine
Meclizine
Promethazine |
|
Definition
|
|
Term
|
Definition
2nd gen H1 Antagonist
No sedation
Do NOT mix with antacid due to decreased bioavailability. |
|
|
Term
|
Definition
2nd Gen H1 Antagonist
Mild sedative |
|
|
Term
Fexofenadine
Loratidine
Cetirizine |
|
Definition
|
|
Term
Cimetidine
Nizatidine
Famotidine
Ranitidine |
|
Definition
H2 Receptor Blockers
Use- GI disturbances
Cimetidine - endocrine (gynocomastia, galactorrhea), CNS prob in elderly |
|
|
Term
|
Definition
H1 receptor antagonist - treat allergies and motion sickness
H2 antagonists- inhibit acid secretion, peptic ulcer disease, gerd |
|
|
