Shared Flashcard Set

Details

Antihistamines/Migraine Rxs
N/A
31
Medical
Professional
02/17/2010

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Cards

Term
Ergot alkaloids (3)
Definition
Used for migraines

Ergotamine
Dihydroergotamine
Methylsergide
Term
Ergot alkaloids contraindications (3)
Definition
Pregnancy
Coronary or peripheral artery dz
Liver and/or renal dz
Term
Methylsergide consideration
Definition
Should not be used longer than 6 months, could cx retroperitoeal, cardiac, or lung fibrosis

Can be used prophylactically
Term
Ergot alkaloid side effects (4)
Definition
nausea
vasoconstriction
leg weakness
muscle pain
Term
Triptans (5)
Definition
Used for migraines

Sumatriptan
Rizatriptan
Almotriptan
Naratriptan
Zolmitriptan
Term
Triptan considerations
Definition
Not used for prophylaxis or long term use
Term
Triptan contraindications (4+1)
Definition
Hx of ischemia
Cerebrovascular or peripheral vasc. dz
Uncontrolled HTN
w/ MAO inh

NARATRITAN should not be used in renal or hepatic dz pts
Term
Triptan side effects (6)
Definition
nausea
malaise
dizziness
weakness
dry mouth
parasthesia
Term
First generation H1 rec antagonists (6)
Definition
Diphenhydramine
Chlorpheniramine
Pyrilamine
Hydroxyzine
Promethazine
Doxepin
Term
First generation H1 rec antagonists
side effects
Definition
SEDATION

Dizziness, fatigue, nervousness, tremor
Loss of appetite, N/V
Hypersensitivity rxn (dermatitis, fever, photosensitivity)
Term
Second generation H1 rec antagonists (4)
Definition
Cetrizine
Loratidine
Desloratidine
Fexofenadine
Term
Second generation H1 rec antagonists
side effects
Definition
Metabolized by P450, so Rx interactions

NO anticholinergic effects
Minimal sedation, drowsiness
Term
Antihistamine uses
Definition
Acute allergic rxns
Itching
Cold & Flu

Dyphenhydramine used for early Parkinson's

Promethazine for N/V

First gen. for somnelence

Diphenhydramine, cyclizine, promethazine for prophylaxis and motion sickness
Term
Diphenhydramine
Definition
First generation H1 rec antagonist
Term
Pyrilamine
Definition
First generation H1 rec antagonist
Term
Hydroxyzine
Definition
First generation H1 rec antagonist
Term
Promethazine
Definition
First generation H1 rec antagonist
Term
Doxepin
Definition
First generation H1 rec antagonist
Term
Chlorpheniramine
Definition
First generation H1 rec antagonist
Term
Cetrizine
Definition
Second generation H1 rec antagonist
Term
Loratidine
Definition
Second generation H1 rec antagonist
Term
Desloratidine
Definition
Second generation H1 rec antagonist
Term
Fexofenadine
Definition
Second generation H1 rec antagonist
Term
Sumatriptan
Definition
Triptan
Term
Rizatriptan
Definition
Triptan
Term
Almotriptan
Definition
Triptan
Term
Naratriptan
Definition
Triptan
Term
Zolmitriptan
Definition
Triptan
Term
Methylgerside
Definition
Ergot alkaloid
Term
Ergotamine
Definition
Ergot alkaloid
Term
Dihydroergotamine
Definition
Ergot alkaloid
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