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Antifungals and antivirals
N/A
18
Pharmacology
Undergraduate 3
10/08/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Antifungals
2 groups covered
Definition
Superficial mycosis and systemic mycosis (most dangerous)
Term
Amphotericin B is the DOC for:
Definition
Systemic infections but highly toxic
Only used for progressive and fatal infections
Term
Amphotericin B route
Definition
IV Over 2-4 hrs
Term
Amphotericin B is detected for:
Definition
Up to a year after withdrawal
Term
Amphotericin B adverse effects
Definition
Nephrotoxicity- check kidney fxn every 3-4 days
Term
Azole drug interactions
Definition
Inhibits CYP 450 enzyme
Drug levels would Inc bc nothing is getting metabolized
- dec levels of those drugs
- cisapride, pimozide, dofetilide, quinidine
Term
Flucytosine used for:

Used in combo with:
Definition
Serious infections if candida and crytococcus neoformans

Amphotericin B
Term
Flucytosine adverse effects
Definition
Bone marrow suppression
Monitor renal fxn
Term
Superficial infections
Definition
Tinea pedis- athletes foot
Tinea corporis- ringworm
tinea cruris- jock itch
Tinea capitus- griseofulvin
Term
Acyclovir used for:
Definition
HSV and VZV
Term
Ganciclovir used for:
Definition
Cytomegalovirus (CMV)
Term
Ganciclovir adverse effects
Definition
Teratogenic
Can cause harm to baby if pregnant
Term
Different type of Hep
Definition
A, B, C, D, E, G
Term
Hep C occurs through:
Definition
Blood exchange
Term
Interferon alpha used for:
Definition
Hep B and C
Term
Interferon alpha
Used for how long?
Definition
12 months of tx but usually relapse after tx withdrawal
Term
Interferon alpha adverse effects
Definition
Depression
Term
Hep B transmission through:
Definition
Blood or semen
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