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antidepressants
antidepressants
42
Medical
Graduate
02/24/2011

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Cards

Term
name MAOIs
Definition
phenelzine, tranylcypromine, selegilline
Term
MAOI side effects
Definition
hyperadrenergic crises, hypertensive crises (can't eat anything aged; characterized by severe HTN)
Term
MAOI time to therapy
Definition
2-4 weeks
Term
name TCAs
Definition
amitriptyline, imipramine, clomipramine, nortriptyline
Term
TCA side effects
Definition
orthostatic hypotension, anticholinergic effects, cardiac toxicity, sexual dysfunction, small therapeutic windown
Term
OCD medical treatment
Definition
clomipramine
Term
name SNRIs
Definition
venlafaxine, duloxetine
Term
effexor
Definition
venlafaxine (available in XR formulation)
Term
cymbalta
Definition
duloxetine
Term
name SSRIs
Definition
fluoxetine, citalopram, escitalopram, fluvoxamine, paroxetine, sertraline
Term
prozac
Definition
fluoxetine (longer wash-out period for MAOI's because of long-lasting metabolite)
Term
celexa
Definition
citalopram
Term
lexapro
Definition
escitalopram
Term
luvox
Definition
fluvoxamine
Term
paxil
Definition
paroxetine
Term
zoloft
Definition
sertraline
Term
SSRI side effects
Definition
GI upset, headache, neuromuscular restlessness, insomnia, sexual dysfunction
Term
name NDRI
Definition
buproprion
Term
wellbutrin
Definition
buproprion (available in SR and XL formulations)
Term
zyban
Definition
buproprion
Term
buproprion indications
Definition
smoking cessation, ADHD
Term
name alpha 2 antagonist
Definition
mirtazapine
Term
remeron
Definition
mirtazapine
Term
mirtazapine side effects
Definition
sedation, but only at low dose; weight gain
Term
name serotonin antagonist and RIs
Definition
trazodone, nefazodone
Term
trazodone side effects
Definition
sedation
Term
nefazodone side effects
Definition
fatal hepatitis
Term
enuresis medical treatment
Definition
imipramine
Term
serotonin rebound
Definition
from abrupt cessation of SSRIs (discontinuation syndrome), common in paroxetine and venlafaxine
Term
use of TCA secondary amines
Definition
increase norepinephrine; used for sleep problems or neuropathic pain
Term
name TCA secondary amines
Definition
norepinephrine increase (desipramine, nortryptiline, amoxapine)
Term
name TCA tertiary amines
Definition
serotonin increase (clomipramine, imipramine)
Term
bupropion main advantage
Definition
no sexual dysfunction like in SSRIs
Term
buprprion side effects
Definition
lowered seizure threshold
Term
venlafaxine dose-dependent profile
Definition
pro-serotonergic up to 150mg, pro-noradrenergic 150-300mg
Term
venlafaxine main advantage
Definition
low protein binding: safe
Term
venlafaxine side effects
Definition
idiopathich hypertension (CHECK BP)
Term
mirtazapine main advantage
Definition
no sexual dysfunction
Term
duloxetine side effects
Definition
idiopathic hypertension (CHECK BP)
Term
nefazadone main advantage
Definition
no sexual dysfunction
Term
anti-depressants and increased suicide?
Definition
yes, but does not make people suicidal; just gives them the motivation to carry out the act
Term
serotonin syndrome
Definition
due to SSRIs AND MAOIs, causing too much serotonin; think myoclonus and autonomic instability
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