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antiplatelet/analgesic/anti-inflammaory; nonselective COX1/COX2 inhibitor. |
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antiplatelet; nonselective COX1/COX2 inhibitor |
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antiplatelet/anti-inflammatory; selective COX2 inhibitor |
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analgesic; COX3 inhibitor. Can cause liver tox |
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antiplatelet; phosphodiesterase inhibitor → ↑ cAMP. Blocks adenosine reuptake |
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antiplatelet; phosphodiesterase inhibitor → ↑ cAMP. Blocks adenosine reuptake |
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antiplatelet; adenylate cyclase activator → ↑ cAMP |
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antiplatelet; inhibits ADP activation of GPIIb/IIIa → inhibits aggregatory effect of platelets |
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antiplatelet; synthetic peptide that blocks GPIIB/IIIA receptors |
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antiplatelet; antibody that blocks GPIIB/IIIA receptors |
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thrombolytic; forms active complex with plasminogen. Strongly immunogenic |
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thrombolytic; directly cleaves plasminogen → plasmin |
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thrombolytic; form a complex with plasminogen and fibrin that localizes it to the clot |
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Definition
recombinant thrombolytic that works like tPA. |
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antispasmodic; acts as GABA agonist at multiple levels in the spinal cord. |
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antispasmodic; pre-synaptic α2 agonist to inhibit spinal cord motoneurons |
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Definition
treats malignant hyperthermia and neuroleptic malignant syndrome; blocks ryanodine receptor sequestering Ca2+ in the sarcoplasmic reticulum. |
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antispasmodic; works in RAS and spinal cord → sedation and altered perception of pain |
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antispasmodic; generalized sedative actions in spinal cord and subcortical areas → inhibits multisynaptic reflexes |
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antispasmodic and fibromyalgia tx; central action at the brainstem |
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antispasmodic; generalized sedative action |
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antispasmodic and tetanus tx; generalized sedative action |
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antispasmodic and PD tx; generalized sedative action in the medulla and cerebral motor centers |
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Definition
antispasmodic; central α2 agonist |
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Definition
antispasmodic; prevents docking and release of Ach vesicles to interrupt nerve conduction |
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Definition
fibromyalgia tx; GABA analogue that binds α2 subunit of Ca channel alleviating neuropathic pain, anxiety, and pain syndromes |
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Definition
anticoagulant; binds ATIII to ↑ its activity |
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Definition
LMWt heparin anticoagulant; binds ATIII to ↑ its activity |
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Definition
LMWt heparin anticoagulant; binds ATIII to ↑ its activity |
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Definition
LMWt heparin anticoagulant; binds ATIII to ↑ its activity |
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Term
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Definition
LMWt heparin anticoagulant; binds ATIII to ↑ its activity |
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Definition
LMWt heparin anticoagulant; binds ATIII to ↑ its activity |
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Definition
LMWt heparin anticoagulant; binds ATIII to ↑ its activity |
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Definition
LMWt heparin anticoagulant; binds ATIII to ↑ its activity |
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Definition
anticoagulant; inactivates Xa |
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Definition
anticoagulant; direct thrombin inhibitor. Independent action of ATIII. Smaller than ATIII so it can get into the clot and work there as well. |
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Definition
anticoagulant; recombinant for of hirudin |
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Term
Bivalirudin/argatroban/melagatran/dabigatran |
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Definition
2nd gen direct thrombin inhibitors; oral admin |
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Definition
anticoagulant; competes with vit K epoxide to block carboxylation of II, VII, IX, X, protein C and S. |
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Definition
anticoagulant; competes with vit K epoxide to block carboxylation of II, VII, IX, X, protein C and S. |
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Definition
anticoagulant; competes with vit K epoxide to block carboxylation of II, VII, IX, X, protein C and S. |
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anti-diarrheal; coats the stomach |
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anti-diarrheal; μ receptor agonist |
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H1 antagonist/1st gen; treats allergies and colds |
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H1 antagonist/1st gen; treats allergies and colds |
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H1 antagonist/1st gen; treats allergies and colds |
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H1 antagonist/2nd gen; treats allergies and colds |
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H1 antagonist/1st gen; allergies and colds |
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2nd gen H1 antagonist; non-sedating for cold/hay fever |
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analgesic; μ receptor metabolized to morphine |
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cough suppressant; non-narcotic |
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systemic and topical decongestant |
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systemic decongestant; precursor of methamphetamine |
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smoking cessation as part of CBT |
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Definition
smoking cessation as part of CBT |
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Nicotine Transdermal patch |
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Definition
smoking cessation as part of CBT |
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What are some differences between unfractionated heparin and LMWT heparin? |
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Definition
LMWt hep has more specific stabilization of ATIII-Xa complex (less ATIII-thrombin). LMWt has less risk for HIT. LMWt has better regularity between molecules → more predictable. |
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