Term
Name a plant compound which exhibits Anticholinesterase activity. G and S. |
|
Definition
Physostigmine, Physostigma venenosum |
|
|
Term
Synthetic compounds with this activity include: |
|
Definition
Insecticides and Nerve Poisons |
|
|
Term
|
Definition
- Inhibitor of acetylcholinesterase resulting in increased acetylcholine in synapses and stimulation of - postganglionic muscarinic nerve receptors - postganglionic cholinergic sweat gland receptors - ganglionic receptors - skeletal muscle nerve receptors |
|
|
Term
Physiological cholinergic effects in autonomic nervous system: (3) |
|
Definition
- diaphoresis (intense sweating) - reduced heart rate - smooth muscle stimulation in intestines and bladder |
|
|
Term
physostigmine: Genus and species: common names: geography: Origin: Ethnomedical issues |
|
Definition
Physostigma venenosum in Fabaceae CN: calabar, ordeal, esere bean Geo:rainforest of west Africa Origin: Efik peopl eof the Calabar region of south-eastern Nigeria Ethnomedical uses: Dry beans as ordeal poison in trials for witchcraft. carried for protectin against witchcraft. |
|
|
Term
Physostigmine: Treats (2): Neostigmine, pyridostigmine, demercarium are used as/to? edrophonium: |
|
Definition
treats: glaucoma, and is antidote for anticholinergic poisoning NP and D: intestinal stimulant, treatment of myasthenia gravis E: used to diagnose and treat myasthenia gravis |
|
|
Term
Physostigmine (eserine) chemical class: Derivatives: Physostigmine ---> |
|
Definition
chem: alkaloid Physostigmine ---> neostigmine |
|
|
Term
|
Definition
neostigmine ----> edrophonium |
|
|