Shared Flashcard Set

Details

Antibiotics
Fitz/Lamango (PDA II) Exam 4
101
Pharmacology
Professional
03/27/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

 

 

 

Penicillins

Definition

Penicillin G (Pfizerpen®)

Penicillin V (Veetids®)

 

MOA: Inhibits bacterial cell wall synthesis

 

Bacteriacidal

 

Spectrum: Strept, Staph, T. palladium, B. fragilis (above the diaphragm)

Term

 

 

 

 

Penicillin G

Definition

Pfizerpen®

 

Also known as Benzyl Penicillin

 

Not absorbed orally, mostly given IM or IV

 

Used as DOC for meningitis

 

Penicillin (Beta Lactam Antibiotics)

Term

 

 

 

Penicillin V

Definition

Veetids®

 

 

Given orally

 

 

Penicillin (Beta Lactam Antibiotic)

Term

 

 

 

Penicillinase Resistant Penicillins

Definition

Methacillin

Oxacillin

Dicloxacillin (Dycill®)

Nafcillin (Unipen®)

Cloxacillin

 

MOA: Inhibits bacterial cell wall synthesis, resistant to penicillinase

 

Spectrum: Staph only

Term

 

 

 

Methacillin

Definition

No Brand Name

 

 

IV only

 

 

Penicillinase Resistant Penicillin

(Beta Lactam Antibiotic) 

Term

 

 

 

Oxacillin

Definition

No Brand Name

 

 

Available orally

 

 

Penicillinase Resistant Penicillin

(Beta Lactam Antibiotic)

Term

 

 

 

Dicloxacillin

Definition

Dycill®, Pathocil®

 

 

Available orally

 

 

Penicillinase Resistant Penicillin

(Beta Lactam Antibiotic)

Term

 

 

 

Nafcillin

Definition

Unipen®, Nallpen®

 

Not given PO, only IV or IM

 

Only penicillin excreted in bile

 

Penicillinase Resistant Penicillin

(Beta Lactam Antibiotic)

Term

 

 

 

Cloxacillin

Definition

No Brand Name

 

 

Available orally

 

 

Penicillinase Resistant Penicillin

(Beta Lactam Antibiotic)

Term

 

 

 

Aminopenicillins

Definition

Ampicillin (Principen®)

Amoxicillin (Amoxil®)

 

MOA: Inhibits bacterial cell wall synthesis

 

Spectrum: Stept, E. coli, Proteus mirabilis, H. influenzae, ear infections 

Term

 

 

 

Ampicillin

Definition

Principen®

 

 

 

 

 

Aminopenicillin (Beta Lactam Antibiotic)

Term

 

 

 

Amoxicillin

Definition

Amoxil®

 

 

Better absorbed orally than ampicillin

 

 

Aminopenicillin (Beta Lactam Antibiotic)

Term

 

 

 

Carboxypenicillins

Definition

Carbenicillin (Geocillin®)

Ticarcillin (Ticar®)

 

MOA: Inhibits bacterial cell wall synthesis

 

Spectrum: Strept, E. coli, Proteus mirabilis, Indole (+) proteus, anaerobes, Klebsiella, Enterobacter, H. influenzae, Serratia, Pseudomonas

Term

 

 

 

Carbenicillin

Definition

Geocillin®

 

IV & IM only

 

 

 

Carboxypenicillin (Beta Lactam Antibiotic)

Term

 

 

 

Ticarcillin

Definition

Ticar®

 

 

IV only

 

 

Carboxypenicillin (Beta Lactam Antibiotic)

Term

 

 

 

Ureidopenicillins

Definition

Pipercillin (Pipracillin®)

Mezlocillin (Mezlin®)

Azlocillin (Azlin®)

 

MOA: Inhibits bacterial cell wall synthesis

 

Spectrum: Strep, E. coli, Proteus mirabilis, Indole (+) proteus, Anaerobes, Klebsiella, Enterobacter, H. influenzae, Serratia, Pseudomonas

Term

 

 

 

Pipercillin

Definition

Pipracillin®

 

 

IV only

 

 

Ureidopenicillin (Beta Lactam Antibiotic)

Term

 

 

 

Mezlocillin

Definition

Mezlin®

 

 

Not used often

 

 

Ureidopenicillin (Beta Lactam Antibiotic)

Term

 

 

 

Azlocillin

Definition

Azlin®

 

 

Not used often

 

 

Ureidopenicillin (Beta Lactam Antibiotic)

Term

 

 

 

Penicillins w/ Beta Lactamase Inhibitors

Definition

Ampicillin/Sulbactam (Unasyn®)

Amoxicillin/Clavulanic Acid (Augmentin®)

Ticarcillin/Clavulanic Acid (Timentin®)

Pipericillin/Tazobactam (Zosyn®)

 

MOA: Inhibits bacterial cell wall synthesis and inhibits beta lactamases

 

Spectrum: Strep, E. coli, Proteus mirabilis, Indole(+) proteus, Anaerobes, Klebsiella, Enterobacter, H influenzae, (Zosyn® & Timentin®): Serratia, Pseudomonas

Term

 

 

 

Ampicillin/Sulbactam

Definition

Unasyn®

 

 

 

 

Penicillin w/ Beta Lactamase Inhibitor

(Beta Lactam Antibiotic)

Term

 

 

 

Amoxicillin/Clavulanic Acid

Definition

Augmentin®

 

 

Only combo given orally

 

 

Penicillin w/ Beta Lactamase Inhibitor

(Beta Lactam Antibiotic)

Term

 

 

 

Ticarcillin/Clavulanic Acid

Definition

Timentin®

 

 

 

 

Penicillin w/ Beta Lactamase Inhibitor

(Beta Lactam Antibiotic)

Term

 

 

 

Pipericillin/Tazobactam

Definition

Zosyn®

 

 

 

 

Penicillin w/ Beta Lactamase Inhibitor

(Beta Lactam Antibiotic)

Term

 

 

 

 1st Generation Cephalosporins

Definition

Cephalexin (Keflex®)

Cefadroxil (Duricef®)

Cefazolin (Ancef®)

Cephalothin (Keflin®)

Cephadrine (Velosef®)

Cephaprin (Cefadyl®)

Cephaloglycin (Kafocin®)

Cephaloridine (Loridine®)

 

 

MOA: Inhibits bacterial cell wall synthesis

 

Bacteriacidal

 

Spectrum: More G+ than G-

Term

 

 

 

Cephalexin

Definition

Keflex®

 

 

Most commonly used

 

 

1st Generation Cephalosporins

(Beta Lactam Antibiotic)

Term

 

 

 

Cefadroxil

Definition

Duricef®

 

 

Used sometimes

 

 

1st Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefazolin

Definition

Ancef®, Kefazole®

 

 

 

 

1st Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cephalothin

Definition

Keflin®

 

 

 

 

1st Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cephadrine

Definition

Velosef®

 

 

 

 

1st Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cephaprin

Definition

Cefadyl®

 

 

 

 

1st Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cephaloglycin

Definition

Kafocin®

 

 

 

 

1st Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cephaloridine

Definition

Loridine®

 

 

 

 

1st Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

2nd Generation Cephalosporins

Definition

Cefamandol (Mandol®)

Cefoxitin (Mefoxin®)

Ceforanide (Precef®)

Cefuroxime (Zinacef®)

Cefuroxime axetil (Ceftin®)

Loracarbef (Lorabid®)

Cefaclor (Ceclor®)

Cefonioid (Monocid®)

Cefotetan (Cefotan®)

Cefmetazole (Zefazone®)

Cefprozil (Cefzil®)

 

MOA: Inhibits bacterial cell wall synthesis

 

Bacteriacidal

 

Spectrum: Same G+ activity as 1st gen, more G- activity

Term

 

 

 

Cefamandol

Definition

Mandol®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefoxitin

Definition

Mefoxin®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Ceforanide

Definition

Precef®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefuroxime

Definition

Zinacef®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefuroxime axetil

Definition

Ceftin®

 

 

Most commonly used

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Loracarbef

Definition

Lorabid®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefaclor

Definition

Ceclor®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefonioid

Definition

Monocid®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefotetan

Definition

Cefotan®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefmetazole

Definition

Zefazone®

 

 

 

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefprozil

Definition

Cefzil®

 

 

Most commonly used

 

2nd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

3rd Generation Cephalosporins

Definition

Moxalactam (Moxam®)

Ceftizoxime (Cefizox®)

Ceftazidime (Fortaz®)

Cefixime (Suprax®)

Cefotaxime (Claforan®)

Cefoperazone (Cefobid®)

Ceftriaxone (Rocephin®)

Cefpodoxime (Vantin®)

 

MOA: Inhibits bacterial cell wall synthesis

 

Bacteriacidal

 

Spectrum: More G- activity than 1st or 2nd generation

Term

 

 

 

Moxalactam

Definition

Moxam®

 

 

 

 

3rd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Ceftizoxime

Definition

Cefizox®

 

 

 

 

3rd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Ceftazidime

Definition

Fortaz®

 

 

 

 

3rd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefixime

Definition

Suprax®

 

 

Used commonly

 

 

3rd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefotaxime

Definition

Claforan®

 

 

Commonly used IM

 

 

3rd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefoperazone

Definition

Cefobid®

 

 

 

 

3rd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Ceftriaxone

Definition

Rocephin®

 

 

Commonly used, IM only

 

3rd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Cefpodoxime

Definition

Vantin®

 

 

Used sometimes

 

3rd Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

4th Generation Cephalosporins

Definition

Cefepime (Maxipime®)

 

MOA: Inhibits bacterial cell wall synthesis

 

Bacteriacidal

 

Spectrum: G+ equal to other generations, greater G-

Term

 

 

 

Cefepime

Definition

Maxipime®

 

 

 

 

4th Generation Cephalosporin

(Beta Lactam Antibiotic)

Term

 

 

 

Carbapenems

Definition

Doripenem (Doribax®)

Ertapenem (Invanz®)

Meropenem (Merrem®)

Imipenem/Cilastatin (Primaxin®)

 

 

MOA: Inhibits bacterial cell wall synthesis

 

Spectrum: Broad spectrum (G+, G-)

Term

 

 

 

Doripenem

Definition

Doribax®

 

 

 

 

Carbapenem (Beta Lactam Antibiotic)

Term

 

 

 

Ertapenem

Definition

Invanz®

 

 

Used frequently at the hospital

 

 

Carbapenem (Beta Lactam Antibiotic)

Term

 

 

 

Meropenem

Definition

Merrem®

 

 

 

 

Carbapenem (Beta Lactam Antibiotic)

Term

 

 

 

Imipenem/Cilastatin

Definition

Primaxin®

 

 

 

 

Carbapenem (Beta Lactam Antibiotic)

Term

 

 

 

Monobactams

Definition

Aztreonam (Azactam®)

 

 

MOA: Inhibits bacterial cell wall synthesis

 

 

Spectrum: Mostly G-

Term

 

 

 

Aztreonam

Definition

Azactam®

 

 

 

 

Monobactam (Beta Lactam Antibiotic)

Term

 

 

 

Sulfonamides

Definition

Sulfisoxazole

Sulhamethoxazole (Bactrim®)

Sulfacetamide (Klaron®)

Sulfasalazine (Azulfidine®)

Mafenide (Sulfamylon®)

Silver Sulfadiazine (Silvadene®)

 

MOA: Interferes with bacterial DNA synthesis  by mimicking PABA to inhibit the formation of dihydrofolic acid

 

Aren't really used as antibiotics

Term

 

 

 

Sulfisoxazole

Definition

No Brand Name

 

 

 

 

Sulfonamide

Term

 

 

 

Sulfamethoxazole

Definition

Bactrim®

 

 

Combined with Trimethoprim, has G+ and G- activity

 

 

Sulfonamide

Term

 

 

 

Sulfacetamide

Definition

Klaron®

 

 

 

 

Sulfonamide

Term

 

 

 

Sulfasalazine

Definition

Azulfidine®

 

 

 

 

Sulfonamide

Term

 

 

 

Mafenide

Definition

Sulfamylon®

 

 

 

 

Sulfonamide

Term

 

 

 

Silver sulfadiazine

Definition

Silvadene®

 

 

Used as a topical antibiotic for burns

 

 

Sulfonamide

Term

 

 

 

Tetracyclines

Definition

Tetracycline

Demeclocycline (Declomycin®)

Minocycline (Minocin®)

Oxytetracycline

Doxycycline (Vibramycin®)

Chlortetracycline (Aureomycin®)

 

MOA: Inhibits bacterial protein synthesis

 

Do not take with Calcium, Magnesium, Zinc, ect due to chelation

 

Can cause Fanconi's syndrome if taken when outdated

 

Spectrum: G+, G-, Rickettsia, Chlamydial, Mycoplasmal

Term

 

 

 

Tetracycline

Definition

No Brand Name

 

 

 

 

Tetracycline

Term

 

 

 

Demeclocycline

Definition

Declomycin®

 

 

Used for SIADH

 

 

Tetracycline

Term

 

 

 

Minocycline

Definition

Minocin®

 

 

 

 

Tetracycline

Term

 

 

 

Oxytetracycline

Definition

No Brand Name

 

 

 

 

Tetracycline

Term

 

 

 

Doxycycline

Definition

Vibramycin®

 

 

Most commonly used

 

Tetracycline

Term

 

 

 

Chlortetracycline

Definition

Aureomycin®, Lederel®

 

 

 

 

Tetracycline

Term

 

 

 

Aminoglycosides

Definition

Kanamycin

Amikacin (Amikin®)

Tobramycin (Nebcin®)

Gentamicin (Garamycin®)

Neomycin (Mycifradin®)

Netilmicin (Netromycin®)

Paromomycin

Streptomycin

Spectinomycin

 

MOA: Inbibits bacterial protein synthesis

 

SE: Nephrotoxicity, Ototoxicity

 

Spectrum: Mostly G-

Term

 

 

 

Kanamycin

Definition

No Brand Name

 

 

 

 

Aminoglycoside

Term

 

 

 

Amikacin

Definition

Amikin®

 

 

 

 

Aminoglycoside

Term

 

 

 

Tobramycin

Definition

Nebcin®

 

 

 

 

Aminoglycoside

Term

 

 

 

Gentamycin

Definition

Garamycin®

 

 

 

 

Aminoglycoside

Term

 

 

 

Neomycin

Definition

Mycifradin®

 

 

 

 

Aminoglycoside

Term

 

 

 

Netilmicin

Definition

Netromycin®

 

 

 

 

Aminoglycoside

Term

 

 

 

Paromomycin

Definition

No Brand Name

 

 

 

 

Aminoglycoside

Term

 

 

 

 Streptomycin

Definition

No Brand Name

 

 

 

 

Aminoglycoside

Term

 

 

 

Spectinomycin

Definition

No Brand Name

 

 

 

 

Aminoglycoside

Term

 

 

 

Macrolides

Definition

Erythromycin estolate

Erythromycin ethyl succinate (E.E.S)

Clarithromycin (Biaxin®)

Azithromycin (Zithromax®)

Dirithromycin

 

MOA: Inhibits ribosomal protein biosynthesis by inhibiting translocation of aminoacyl t-RNA

 

Spectrum: Mainly G-

Term

 

 

 

Erythromycin estolate

Definition

No Brand Name

 

 

 

 

Macrolide

Term

 

 

 

Erythromycin ethyl succinate

 

Definition

E.E.S

 

 

Commonly Used

 

 

Macrolide

Term

 

 

 

Clarithromycin

Definition

Biaxin®

 

 

Commonly used

 

 

Macrolide

Term

 

 

 

Azithromycin

Definition

Zithromax®

 

 

Commonly used

 

 

Macrolide

Term

 

 

 

Dirithromycin

Definition

No Brand Name

 

 

 

 

Macrolide

Term

 

 

 

Fluoroquinolones

Definition

Ciprofloxacin (Cipro®)

 

MOA: Inhibits enzymes in the winding of bacterial DNA

 

Spectrum: E. coli, Pseudomonas aeruginosa, Klebsiella, Proteus mirabilis, Shigella, Campylobacter jejunii, H. influenzae, S. aureus (including MRSA), S, pyogenes, S. pneumoniae, N. gonnorhea

Term

 

 

 

Ciprofloxacin

Definition

Cipro®

 

 

 

 

Fluoroquinolone

Term

 

 

 

Miscellanous Antibiotics

Definition

Lincomycin (Lincocin®)

Clindamycin (Cleocin®)

Chloramphenicol

Vancomycin (Vancocin®)

Bacitracin

Term

 

 

 

Lincomycin

Definition

Lincocin®

 

 

MOA: Same as macrolides; Inhibits ribosomal protein biosynthesis by inhibiting translocation of aminoacyl t-RNA

 

Lincosamide (Miscellaneous)

Term

 

 

 

Clindamycin

Definition

Cleocin®

 

 

MOA: Same as macrolides; Inhibits ribosomal protein biosynthesis by inhibition translocation of aminoacyl t-RNA

 

Lincosamide (Miscellaneous)

Term

 

 

 

Chloramphenicol

Definition

No Brand Name

 

 

MOA: Bacteriostatic; Inhibits protein synthesis in bacteria by binding to to 50S ribosomal subunit

 

Miscellaneous

Term

 

 

 

Vancomycin

Definition

Vancocin®

 

 

 

 

Miscellaneous

Term

 

 

 

Bacitracin

Definition

No Brand Name

 

 

Mainly active against G+

 

 

Miscellaneous

Supporting users have an ad free experience!