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Antibiotics
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84
Microbiology
Professional
12/08/2011

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Cards

Term
Streptococcus
Definition
penicllins except for enterococcus which needs penicillin + aminoglycoside
Term
S. aureus (not MRSA)
Definition
nafcillin/oxacillin, cephalosporin, tetracyclines (minocycline), clindamycin, moxifloxacin
Term
MRSA outpatient
Definition
clindamycin, minocycline, TMP-SMX, (only outpatient when limited to skin and well-drained)
Term
Severe MRSA: nonVISA
Definition
vancomycin, daptomycin
Term
Severe MRSA: VISA
Definition
televancin and linezolid
Term
How does the new cephalosporin, ceftaroline work against MRSA?
Definition
binds MRSA mecA gene product PBB2a
Term
S. epidermidis
Definition
oxacillin resistant!!! treat with vancomycin
Term
S. lugdenensis
Definition
vancomycin (remove device)
Term
S. Saprophyticus
Definition
TMP-SMX and flouroquinolones
Term
B. Cereus
Definition
nonGI infections=> vancomycin, clindamycin, gentamicin and ciprofloxacin
Term
Listeri monocytogenes
Definition
ampicillin and erythromycin
Term
Corynebacterium diphtheria
Definition
penicillin or erythromycin
Term
Nocardia asteroides
Definition
sulfa drugs; if severe, use amikacin + beta lactams
Term
Borrelia Burgdorferi
Definition
Beta lactams, tetracyclines, erythromycin
Term
Borrelia recurrentis
Definition
low dose to prevent Jarisch Herxheimmer rxn
Term
Leptospira interogans
Definition
doxycycline, penicillin, flouroquinolones
Term
Ricketsia Ricketsii
Definition
tetracycline, chloramphenicol, flouroquinolones
Term
Ricketsia prowazekii
Definition
tetracycline and chloramphenicol
Term
Coxiella burnetii
Definition
tetracycline, tetracycline with rifampin, or TMP-SMX
Term
Bartonella henselae
Definition
normal patient= supportive
immunocompromised= erythromycin and doxycycline
Term
Erlichia chafeensis, ehrlichia ewingii and anaplasma phagocytophilum
Definition
tetracycline or chloramphenicol
Term
Pasturella multocida
Definition
beta lactams
Term
Bacillus anthracis
Definition
ciprofloxacin or doxycycline (raxibacumab)
Term
Yersinias Pestis
Definition
streptomycin and tetracycline
Term
Franisella tularensis
Definition
streptomycin or gentamycin
Term
TB
Definition
rifampin, isoniazid, pyrazinamide, ethambutol
Term
TB prophylaxis
Definition
isoniazid
Term
Leprosy
Definition
rifampin, dapsone, clofazimine
Term
2nd line leprosy
Definition
mino, ofloxacin, clarithromycin
Term
Atypical mycobacterium (how long do you treat?)
Definition
azithromycin, clarithromycin, cirpo, 8-24 months tx
Term
Neisseria Gonorrhea
Definition
cefixime and ceftriazone
Term
Neisseria Meningitidis
Definition
rifampin, cipro, parenteral ceftriazone
Term
H. influenzae prophylaxis
Definition
rifampn prophylaxis
Term
B. pertussis
Definition
erythromycin, tetracycline and chloramphenicol
Term
V. cholerae
Definition
supportive (tetracycline might reduce severity/length)
Term
V. Parahemolyticus
Definition
rehydration and antibiotics
Term
V. vulnificans
Definition
tetracyclines, flouroquinolones
Term
campylobacter jejuni
Definition
erythromycin
Term
helicobacter jejuni
Definition
amoxicillin, tetracycline, metronidazole, bismuth salts PPI
Term
legionella
Definition
macrolides (azithro/clarithro), or flouroquinolones
Term
Most travelers diarrhea=
Definition
azithro, cipro, rifaximin
Term
ETEC tx
Definition
flouroquinolones, rifaximin, azithromycin, peptobismol
Term
EHEC tx
Definition
withhold antibiotics
Term
EPEC
Definition
rehydration
Term
Shigella
Definition
rehydration, ciprofloxacin, flouroquinolones
Term
EIEC
Definition
flouroquinolones, rifaximin, azithromycin, peptobismol
Term
EAggEC
Definition
flouroquinolone, firaximin, azithromycin, peptobismol
Term
Salmonella
Definition
cirpo for severe cases, peptobismol,
Term
Typhoid fever
Definition
cipro, azithro, ceftriaxone
Term
Ecoli cystitis
Definition
3 day antibiotic- TMP, cipro
Term
How do you treat bacteroides infection?
Definition
very resistant! (to things like beta lactams, aminoglycosides, erythromycin and tetracycline)
Term
F. necrophorum
Definition
beta lactams, metronidazole, clindamycin, 3rd generation cephalosporin
Term
Tetanus
Definition
penicillin historically but metronidazole is currently recomended
Term
Tx for infant botulism
Definition
babyBIG
Term
What are the antibiotics that can cause C. Diff psuedomembranous colitis?
Definition
clinda, quinolones, cephalosporins
Term
C. diff pseudomembranous colitis
Definition
metronidazole (vanc if severe)
can use probiotics (Sacharomyces boulardii)
Term
C. perfringens
Definition
debridement/remove tissue and massive doses of penicillin and BS cephalosporins, hyperbaric O2 chamber (slows bacterial growht, toxin production and oxidizes theta toxin)
Term
P. aeruginosa
Definition
extended spectrum beta lactam (piperacillin, ticercillin) + aminoglycoside (tobramycin), p. aeruginosa has a beta lactamase
Term
How do you treat a patient with a bacterial infection of the cornea?
Definition
cipro for psuedomonas but not staph; gatifloxacin and moxifloxacin for psuedomonas and staph
Term
P. aeruginosa if resistant to all conventional treatment=
Definition
colistin
Term
Burkholderia pseudomallei
Definition
extended spectrum beta lactam (pipercillin, ticercillin) + aminoglycoside (tobramycin)
Term
B. cepacia
Definition
extended spectrum beta lactam (pipercillin, ticercillin), + aminoglycoside (tobramycin)
Term
aeromonas hydrophilia
Definition
treat diarrhea with bactrim, other infections with flouroquinolones
Term
How do you treat chlamydia strains A-K ocular or genital infections?
Definition
azithromycin or doxycycline (Erythromycin for pregnant women)
Term
Lymphogranuloma venereum
Definition
doxycycline
Term
Neonatal chylamydia conjunctivitis
Definition
erythromycin
Term
Neonatal chlamydia pneumonia
Definition
erythromycin
Term
Psitacosis
Definition
doxycycline, azithromycin and clarithromycin
Term
Chlamydia Pneumoniae
Definition
doxycycline, azithromycin and clarithromycin
Term
Mycoplasma Pneumoniae
Definition
azithromycin
Term
M. Hominis
Definition
resistant to erythromycins so tx with tetracyclines (except resistant to doxy)
Term
Ureaplasma Urealiticum
Definition
macrolides and tetracycline
Term
M. genitalium
Definition
azithromycin 5 day regimen
Term
resistant M genitalium
Definition
moxifloxacin
Term
How do you treat syphilis?
Definition
penicillin (tetracycline if allergy)
Term
Gonoccocus tx (from clinical lecture)
Definition
400mg oral X 1 dose cefixime or 125 mg IM X 1 dose of deeftriazone, + 1 g oral 1 dose azithromycin
Term
NGU treatment
Definition
either azithromycin 1 gram oral dose once or doxycycline 100 mg orally twice daily x 7 days
Term
How do you treat muccopurulent cervicitis?
Definition
azithromycin and cefixime
Term
PID
Definition
ceftriazone 250 mg IM x 1 dose or another 3rd generation cephalosporin+ doxycycline 100 mg 2 x a day x 14 days +/- metronidazole 500 mg 2 x a day x 14 days
Term
Bacterial vaginosis
Definition
metronidazole 500mg orally 2 x a day x 1 week OR clindamycin cream vaginally or metronidazole gel
Term
Yeast vaginitis
Definition
topical antifungals or fluconazole 150 mg orally x 1 dose
Term
Trichomonas vaginalis
Definition
2 gram single dose of metronidazole or tinidazole
Term
Chancroid
Definition
azithromycin and ceftriazone
Term
Syphilis tx (with units)
Definition
benzathine penicillin 2.4 million units IM x 1 dose
if allergic, doxycycline 100mg 2x a day x 14 days
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