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Antibiotics Spectrums
Spectrums of Common antibiotics
27
Medical
Post-Graduate
02/07/2012

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Term
MRSA Antibiotics
Definition
Vancomycin, Trimethoprim-Sulfamethoxazole, Clindamycin, Linezolid, Daptomycin, Tigecycline, Fifth gen Cephalosporins
Term
Pseudomonas Antibiotics
Definition
Ceftazidime, Cefepime, Aztreonam, Levofloxacin, Ciprofloxacin, Carbapenems except Ertapenem, Penicillins with anti-lactimases, Tobramycin>Gentamicin
Term
Vancomycin Resistant Enterococcus Antibiotics
Definition

Ampicillin(Aminopenicillins)

Linezolid

Daptomycin

Tigecycline

Nitrofurantoin

(Tiger LAND)

Term
Vancomycin Spectrum
Definition

Gram positive: Mainly; (ex. Staph, Strep, Enterococcus, Bacillus)

Gram Negative:None

Anaerobic: None

MRSA: Y

VRE: N

Pseudo: N

Other:

Term
Daptomycin Spectrum
Definition

Gram positive:Broad; MRSA, VRE

Gram Negative:None

Anaerobic: None

MRSA:Y

VRE:Y

Pseudo:N

Other: avoid in pulmonary pneumonia

Term
Ciprofloxacin spectrum
Definition

Gram positive:Less

Gram Negative:Good

Anaerobic:Less

Other:

MRSA:N

VRE:N

Pseudo:Y

Term
Moxifloxacin spectrum
Definition

Gram positive:Good (S. Pneumo)

Gram Negative:Ok

Anaerobic:Some

Other:Does not get into urine

MRSA:N

VRE:N

Pseudo:N

Term
Levofloxacin spectrum
Definition

Gram positive:Good(S. pneumo)

Gram Negative: good (Pseudo)

Anaerobic: Weak

Other:

MRSA: N

VRE: N

Pseudo: Y

Term
Trimethoprim-Sulfamethoxazole spectrum
Definition

Gram positive: S. aureus, Nocardia, NOT strep

Gram Negative:Rods

Anaerobic:N

Other:PCP, Toxo

MRSA:Y

VRE:N

Pseudo:Y

Term
Metronidazole Spectrum
Definition

Gram positive:Ok (Clostridium)

Gram Negative: Ok

Anaerobic: Great

Other: Protozoa

MRSA:N

VRE:N

Pseudo:N

Term
Colistin Spectrum
Definition

Gram positive:Not really

Gram Negative:Good (Klebsiella, Acinetobacter)

Anaerobic: Not really

Other:

MRSA:N

VRE:N

Pseudo:Y

Term
Natural Penicillin Spectrum
Definition

Gram positive:

Gram Negative:

Anaerobic:

Other: Mainly Syphilis, GAS, Actinomyces

MRSA:

VRE:

Pseudo:

Term
Aminopenicillins Spectrum
Definition

Gram positive:Good (listeria)

Gram Negative:Some (HiB)

Anaerobic:N

Other:

MRSA:N

VRE:Y

Pseudo:N

Term
Penicillins plus spectrum
Definition

Gram positive:Good (good for mixed oral or GI)

Gram Negative:Some

Anaerobic: Good

Other:Not SPACE (Serratia, Pseudo, Acineto, Citro, Entero)

MRSA:N

VRE:N

Pseudo:N

Term
First generation cephalosporin spectrum
Definition

Gram positive:Good

Gram Negative:weak

Anaerobic:N

Other: good for surgical prophylaxis

MRSA:N

VRE:N

Pseudo:N

Term
Second Generation Cephalosporins spectrum
Definition

Gram positive:Good

Gram Negative:Some

Anaerobic:N

Other:

MRSA:N

VRE:N

Pseudo:N

Term
Third Generation Cephalosporins' spectrum
Definition

Gram positive:Less (S. pneumo)

Gram Negative:More (H. Inf)

Anaerobic:N

Other:

MRSA:N

VRE:N

Pseudo: Ceftazidime

Term
Cefepime Spectrum
Definition

Gram positive:Good

Gram Negative:Good

Anaerobic:Limited

Other:

MRSA:N

VRE:N

Pseudo:Y

Term
Fifth Generation Cephalosporins Spectrums
Definition

Gram positive:Good (S. pneumo)

Gram Negative:Good (Klebsiella)

Anaerobic:

Other:

MRSA:Y

VRE:N

Pseudo:N

Term
Carbepenems' spectrum
Definition

Gram positive:Good  (except MRSA & entero)

Gram Negative:Good including ESBL

Anaerobic: Good

Other:

MRSA:N

VRE:N

Pseudo:Y (not Ertapenem)

Term
Aztreonam Spectrum
Definition

Gram positive:N

Gram Negative:Good

Anaerobic:N

Other:

MRSA:N

VRE:N

Pseudo:Y

Term
Macrolides Spectrum
Definition

Gram positive:S. pneumo and Beta-strep, NOT Staph

Gram Negative:H. inf, Moraxella

Anaerobic: N

MRSA:N

VRE:N

Pseudo:N

Other: Legionella, Mycoplasma, Chlamydia, H. pylori, MAC

Term
Clindamycin Spectrum
Definition

Gram positive:MRSA(Community and D-test neg), TSS, mouth org, osteo

Gram Negative:N

Anaerobic: N

MRSA:Y(Community and D-test neg)

VRE:N

Pseudo:N

Other: Attains high concentrations in abscesses

Term
Linezolid Spectrum
Definition

Gram positive:Cocci only

Gram Negative:N

Anaerobic: Some

MRSA:Y

VRE:Y

Pseudo:N

Other:

Term
Tetracyclines Spectrum
Definition

Gram positive:S. aureus, coag neg staph

Gram Negative:N

Anaerobic: N

MRSA:N

VRE:N

Pseudo:N

Other: Mycoplasma, C. psittaci, Chlamydia, Lyme, Rickettsiae, Acne, Syphilis

Term
Tigecycline Spectrum
Definition

Gram positive:Very broad

Gram Negative:Good

Anaerobic: Good

MRSA:Y

VRE:Y

Pseudo:N

Other: No 3P's, (Pseudo, Proteus, Providencia), Does not get high blood levels or urine levels, best for soft tissue infections

Term
Aminoglycosides Spectrum
Definition

Gram positive:None except in synergy with Beta-lactams for E. Fec

Gram Negative:Esp rods

Anaerobic: None at all

MRSA:N

VRE:N

Pseudo:Tobra>Genta

Other:

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