Term
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Definition
Blocks TRANSPEPTIDASE CROSSLINK.. CIDAL
gm+/gm-(weak)/anerobic/spirochete
POOR CNS
1. extensive skin rashes esp. with mono
REALLY GM + and TREP PAL |
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Term
|
Definition
Extended spectrum penecillin which blocks transpeptidase crosslink
gm+/gm-/anerobic/spirochete
POOR CNS
skin rashes with mono
SINUSITIS |
|
|
Term
|
Definition
For Staph... blocks transpeptidase crosslink
MRSA = MUTATED PENECILLIN BINDING PROTEIN.
gm+narrow/gm-/anerobic/spirochete... decreased sensitivity to lactamase
POOR CNS
skin rashes with mono |
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Term
|
Definition
for pseudomonas blocks transpeptidase crosslinking
gm+/gm-/anerobic/spirochete
POOR CNS
skin rashes with mono
COMBINED AMINOGLYCOSIDE |
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Term
|
Definition
1st generation cehpalosporine binds penecillin bind protein
gm+/- and Spirochetes
REALLY SURGICAL PROPHYLAXIS GM +
NEPHROTOXIC
ok delayed hypersensity penecillin
Proteus, E.coli, Klebsiella |
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Term
|
Definition
3rd generation cephalosporine bind pbp
gm+/- and spirochetes
GOOD CNS
PNEUMONIA AND GM -
ok delayed hypersensity penecillin
MENINGITIS AND GONORRHEA |
|
|
Term
|
Definition
4th generation cephalosporine bind pbp
gm +/- and spirochetes
GOOD CNS
GAINED PSEUDOMONAS
NEPHROTOXIC
ok delayed hypersensity penecillin |
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|
Term
|
Definition
5th generation cephalosporine bind pbp
gm +/- and spirochetes
MRSA-co and MRSA-skin
NEPHROTOXIC
ok delayed hypersensity penecillin |
|
|
Term
|
Definition
secreted grm positive
in periplasm grm negitive
break lactam ring |
|
|
Term
| cephlasporins in general SE |
|
Definition
1. hypersensitivity rxns
2. increases nephrotoxicity of aminoglycosidese
3. disulfram like reactions |
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