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Antibiotic Classes
Antibiotic classes and their spectrums
11
Pharmacology
Post-Graduate
04/05/2011

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Term
First generation/Natural Penicillins
Definition
Penicillin G, Penicillin V
Trepemona Pallidum
Enterococcus
Streptococcus
Penicillin-sensitive Staph
Term
Second generation/B lactamase resistant penicillins
Definition
Methacillin,Dicloaxcillin, nafcillin, oxacillin

methacillin sensitive staph
some strep
Term
Third generation/Aminopenicillins
Definition
Ampicillin, Amoxicillin
1st Gen Pen coverage Trep, Strep Entero
HE(l)P: H. Influenza, Enterococcus, Proteus
Term
Enterococcus
Definition
Gram positive dipolococci
Natural penicillins
Not covered by an cephalosporin
Term
Fourth Generation/Extended Penicillins
Definition
Piperacillin/tozabactram
Ticaricillin/clavulanic acid
Aminopenicillin coverage
Psudomonas
Term
Clavulanic acid, sulbactam
Definition
Added to aminopenicillns to increase coverage:
Enteric gram negatives and anaerobes
Term
Gram negative anaerobes
Definition
Bacterioides
Fusobacterin
Term
Gram positive anaerobes
Definition
Clostridium
Actinomyces
Lactobacillus
Term
First Generation cephalosporins
Definition
cefazolin,cefadroxil, cephalexin
All have PH in name except FAZ and FAD
Strep
Staph- non mrsa
PEcK
Proteus, E. Coli Klebsiella
Term
Second Generation type A Cephalosporins
Definition
Cefaclor, cefuroxime
Strep
Staph- Non MRSA
HEN PEcK: H influenza, Enterobacteriaceae, Nisseria, Proteus, E. Coli, Klebsiella
Term
Enterobacteriacae
Definition
Sallmonella
Shigella
Proteus
Klebsiella
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