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Antiarrhythmics
Exam 2
22
Pharmacology
Post-Graduate
01/07/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Quinidine
Definition

Class 1A

Slows conduction velocity of phase 0

↑ AP duration

↑ refractory period

(interact medium with Na channels)

Term
Procainamide
Definition

Class 1A

(inhibits Na, metabolite inhibits K)

Slows conduction velocity of phase 0

↑ AP duration

↑ refractory period

(interact medium with Na channels)

Term
Lidocaine
Definition

CLass 1B

Slows conduction velocity of phase 0

↓ AP duration

↓ Refractory period

(Interact fast with Na channels)

Term
Flecainide
Definition

Class 1C

Greatly Slows conduction velocity of phase 0

↑ AP duration

↑ refractory period

(interact slowly with Na channels)

Term
Propranolol
Definition
β blocker
Term
Acebutolol
Definition
β blocker
Term
Esmolol
Definition
β blocker
Term
Amiodarone
Definition
Inhibit K channels
Term
Dofetillide
Definition
Inhibit K channels
Term
Verapamil
Definition
Blocks Ca channels
Term
Diltiazem
Definition
Blocks Ca channels
Term

Class 1A

 

Definition

Slows conduction velocity of phase 0

↑ AP duration

↑ refractory period

(interact medium with Na channels)

Term
Class 1B
Definition

Slows conduction velocity of phase 0

↓ AP duration

↓ Refractory period

(Interact fast with Na channels)

Term
Class 1C
Definition

Greatly Slows conduction velocity of phase 0

↑ AP duration

↑ refractory period

(interact slowly with Na channels)

Term
Cinchonism
Definition
Quinidine
Term
Reversible lupus
Definition
Procainamide
Term
Adenosine
Definition

↓ Conduction velocity

↓ Abnormal impulse formation

Term
Interstitial pulmonary fibrosis
Definition
Amiodarone
Term
Hyper/Hypothyroidism
Definition

Amiodarone

Term
Decrease threshhold voltage of phase 0
Definition

Class 1

Class 2

Class 4

Term
The general mechanism by which most drugs supress normal automaticity in ectopic cardiac tissue is
Definition
decreasing slope of phase 4
Term
Will increase levels of digoxin
Definition
Quinidine
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