Shared Flashcard Set

Details

Antiarrhythmics
N/A
29
Pharmacology
Professional
04/04/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
quinidine
Definition
sodium channel blocker
A
Term
procainamide
Definition
sodium channel blocker
A
Term
disopyramide
Definition
sodium channel blocker
A
Term
lidocaine
Definition
sodium channel blocker
B
Term
mexiletine
Definition
sodium channel blocker
B
Term
propafenone
Definition
sodium channel blocker
C
Term
metoprolol
Definition
beta blocker
Term
propranolol
Definition
beta blocker
Term
sotalol
Definition
beta blocker and potassium channel blocker
Term
amiodarone
Definition
potassium channel blocker
Term
diltiazem
Definition
calcium channel blocker
Term
verapamil
Definition
calcium channel blocker
Term
digoxin
Definition
other antiarrhythmic
Term
adenosine
Definition
other antiarrhythmic
Term
flecanide
Definition
sodium channel blocker
C
Term
phenytoid
Definition
sodium channel blocker
B
Term
amiodarone indications
Definition
pulseless VT/VF
wide complex tachycardia
(a-fib)
Term
route for amiodarone
Definition
IV only
(PO off label)
Term
amiodarone actions
Definition
-prolongs myocardial cell action potential
-prolongs refractory period
-K and Na channel blocking
-reduces automaticity of SA node
-reduces contractility and conduction velocity in AV node, ventricles, bundle of His, and Purkinje system
Term
amiodarone adverse effects
Definition
thyroid abnormalities (from iodine)
pulmonary fibrosis
corneal deposits

grey/blue discoloration of skin
CNS/GI disturbance
pro-arrhythmic effects
heart block
nightmares
abnormal LFT
Term
amiodarone drug interactions
Definition
digoxin
warfarin
Term
calcium channel blocker side effects
Definition
constipation
Term
alternative to amiodarone
Definition
digoxin
Term
digoxin mode of action
Definition
Na-K ATPase inhibition
positive inotrope
vagomimetic
Term
digoxin indication
Definition
SVT (not WPW)
Term
drug interactions with digoxin
Definition
coumadin (inc. PT/INR)
quinidine, amiodarone, verapamil (inc. dig level)
spironolactone (dec. renal function)
Term
dig toxicity clinical manefestation
Definition
combo of SVT and AV block

yellow-green vision
Term
What predisposes someone to dig toxicity?
Definition
hypokalemia
Term
How do you counteract a digoxin toxicity?
Definition
Digibind (digoxin-specific Fab fragment
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