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Antiarrhythmic Drugs
Part 5
12
Nursing
Graduate
11/01/2014

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Cards

Term
WHAT IS THE METABOLISM AND EXCRETION OF AMIODARONE?
Definition
CYP 450. RENAL EXCRETION
Term
FOR AMI WHAT IS CLEARANCE INVERSE TO?
Definition
AGE? HIGHER AGE = LESS CLEARANCE (JUST LIKE MOST OTHER DRUGS).
Term
WHAT DOES CLASS 4 BLOCK AND WHAT 2 DRUGS ARE USED?
Definition
CALCIUM CHANNEL BLOCKERS WITH CARDIAC SELECTIVITY. VERAPAMIL AND DILTIAZEM
Term
HOW DOES CLASS 4 WORK?
Definition
DECREASES AV NODE CONDUCTION VELOCITY AND INCREASES REFRACTORY PERIOD. SIMILAR BUT LESSER EFFECT ON SA NODE.
Term
CAN CCBS TERMINATE SVT AND ATRIAL ARRHTHMIAS?
Definition
YES
Term
WHAT IS ADENOSINE A DERIVATIVE OF?
Definition
ATP
Term
HOW DOES ADENOSINE WORK?
Definition
ACTIAVTES G-PROTEIN COUPLE ADENOSINE RECEPTORS TO ACTIVATE K CHANNELS AND BLOCK CALCIUM INFLUX IN SA AND AV NODE AND ATRIAL CONDUCTION. IT ALSO SUPPRESSES CALCIU DEPENDEDNT ACTION POTENTIALS.
Term
WHAT IS THE PLASMA HALF LIFE OF ADENOSINE?
Definition
10 SECONDS
Term
WHAT ARE 4 SIDE EFFECTS OF ADENOSINE?
Definition
AYSTOLE, HEADACHE, FLUSHING, BRONCHOCONSTRICTION. SINUS ARREST IS TYPICALLY FOLLOWED BY A NEW ARRHYTHMIA WHICH RAPDILY CONVERTS TO A SINUS RHYTHM.
Term
WHAT IS MAGNESIUM USED FOR?
Definition
SUPPRESSES TORSADES DE POINTES, DIGOXIN INDUCED VENTRIULAR ARRHYTHMIAS AND MAGNESIUM DEFICIENCY INDUCED ARRHYTHMIAS
Term
WHAT DOES POTASSIUM DO FOR ARRHYTHTMIAS?
Definition
STABILIZE MEMBRANE POTENTIALS.
Term
WHAT 2 THINGS DOES HYPOKALEMIA RESULT IN?
Definition
INCREASE IN AFTER DEPOLARIZATIONS AND ECTOPIC BEATS
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