Shared Flashcard Set

Details

Anti-Histamines/Migraines
Test 2
17
Pharmacology
Professional
02/27/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
H1 Receptors
Definition
G-protein converts PIP2 to IP3 and DAG (inflammation and allergy)
Term
H2 Receptors
Definition
G-protein= ^ cAMP (gastric secretion)
Term
H3 Receptors
Definition
G-protein- Inhibit neurotransmitter release
Term
Diphenhydramine
Definition
1st generation H1 antagonist
-can reduce early parkinson's sx
Term
Chlorpheniramine
Definition
1st generation H1 antagonist
Term
Pyrilamine
Definition
1st generation H1 antagonist
Term
Hydroxyzine
Definition
1st generation H1 antagonist
Term
Promethazine
Definition
1st generation H1 antagonist
-Can treat N&V
Term
Doxepin
Definition
1st generation H1 antagonist
Term
Cetirizine
Definition
2nd generation H1 blocker
Term
Loratidine
Definition
2nd generation H1 blocker
Term
Desloratadine
Definition
2nd generation H1 blocker
Term
Fexofenadine
Definition
2nd generation H1 blocker
Term
Triptans
Definition
5HT1 receptor agonist
-Direct Vasoconstriction
-Presynaptic inhibition on sens neurons
*Can have CV complications
Term
Ergotamine
Definition
5HT agonist (Migraine)
Term
Methysergide
Definition
5HT antagonist
-Can be used prophylactically for migraines
*Don't use longer than 6 mos, can cause fibrosis or int organs
Term
Dihydroergotamine
Definition
5HT agonist (Migraines)
Supporting users have an ad free experience!