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anti-depressants
anti-depressants
11
Pharmacology
Graduate
12/04/2011

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Cards

Term
Imipramine
Definition
TCA
-met to desipramine
MOA: inhib NE, 5-HT reuptake, a1, mACHR, histamine
*cardiotoxic
Treats: depr, enuresis (anti-ACh), Pain, ADHD
Term
Amitriptyline
Definition
TCA
-inhib 5-HT>NE, a1,mACHR, histamine
Term
Desipramine
Definition
TCA
-inhib NE reuptake
*SUDDEN death in Children!
Term
Nortriptyline
Definition
TCA
-inhib NE>5-HT
Term
Bupropion
Definition
-2nd 3rd gen
-psychomotor activation
-depr, NICOTINE WITHDRAWL!!
Term
Venlafaxine
Definition
-2nd 3rd gen
-SE: INC BP (diastolic)
-depression
Term
Trazodone
Nefazodone
Definition
Tra: priapism
-depr
Term
Fluoxetine
Definition
SSRI
--active met
-inhib P450
-dep, OCD, bulimia, phobic anxiety D/O, social phobia
Term
Sertraline
Paroxetine
Fluvoxamine
*Citalopram
Definition
SSRI- inhib 5-HT reuptake
-shorter acting, no met, no inhib of P450
Term
Phenelzine
Definition
-MAO-I irrev inhib MAO-A and B
-long acting
-patient needs tyramine free diet!
-depr, narcolepsy, phobic anxiety D/O, OCD
Term
Selegiline
Definition
-MAO-I B- inc DA--> treats PD (+MDD)
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