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Anti-Arrhythmia Drugs
n/a
10
Biochemistry
Undergraduate 1
05/21/2013

Additional Biochemistry Flashcards

 


 

Cards

Term
Na channel blockers
Definition
quinidine, lignocaine, propafenone, flecainide
Term
quinidine
Definition

class 1a

prolong ap duration

binds to na channels is use dependent manner

useful for: VENTRICULAR ARRHYTHMIAS, PAROXYSMAL RECURRANT ATRIAL FIBRILLATION.

Term
lignocaine
Definition

CLASS 1B

decreased ap duration

 

supress automaticity

useful for: MYOCARDIAL INFARCTION, VENTRICULAR TACHYCARDIAS

Term
Propafenone/flecainide
Definition

minimal change in ap duration

supresses automaticity

increased refractory period

usefor: WPW SYNDROME, RECURRANT TACHYARRYTHMIAS

 

decreased cardiac contractility = contraindicated immediately post MI

Term
Beta Blockers
Definition
Atenolol
Term
Atenolol
Definition

class II antiarrythmic agent

beta blocker

supress automaticity

shorter ap andf longer ref period

decreased conduction in both nodes

useful for: SVT, POST MI

Term
aMiodarone
Definition

class III antiarryhthmic agent = k channel blocker

prolonged ref period and ap

useful for: WPW SYNDROME, VENTRICULAR TACHYCARDIAS, ATRIAL FIBRILLATION

Term
VERAMAPRIL/diltiazem
Definition

class IV antiarryhthmic agent = ca channel blocker

block av node

reduce o2 demand and cardiac work

useful for: PREVENTION OF PAROXYSMAL SVT, REDUCE VENTRICULAR RATE IN ATRIAL FIBRILLATION

 

Term
DIGOXIN
Definition

vagal stimulant

supress av conduction

decrease ventricular rate

useful for: SVT, ATRIAL FIB/FLUTTER

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