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ANS I
Autonomic Nervous System
13
Pharmacology
Graduate
02/18/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
ANS divisions and description
Definition
Sympathetic- fight or flight
Parasym - essential body fn's
Term
Sympathetic NT's
Definition
Epinephrine
Norepinepherine
Term
Parasympatheteic NT's

What is it inactivated by?
Definition
Acetylcholine

Acetylcholinesterase
Term
Sympathetic actions
Definition
Pupil dilation, secretion of renin, blood vessel dilation in muscles, blood vessel constriction in skin/mucous membranes
Term
What innervates the GI tract?
Definition
Enteric neurons
(non-reliant on central nervous system)
Term
6 most common neurotransmitters
Definition
Norepin., Epine., Acetylcholine, Dopamine, Serotonin, Histamine
Term
Cholinergic
Definition
"mediated by Ach"
Term
Neurotransmitter Signaling summary
Definition
Neurotransmitters:
Released from nerve terminals between cells
Triggered by action potential (causing depolarization)
Calcium uptake causes fusion of vesicles of synapses with presynaptic membrane
Contents of vesicles are released
Term
Acetylcholine mediates....
Definition
cholinergic receptors
Term
Cholinergic agonists: 6 steps of neurotransmission
Definition
Synthesis
Storage in vesicles
Release of Ach
Receptor binding
Degradation of Ach
Recycling of choline
Term
What is the rate limiting step of Acetylcholine synthesis?
Definition
Choline reuptake
Term
Ach release
Definition
Na+ channels propagate action potential

Action Potential arrives @ nerve ending

Ca+ channels open, rise in intracelllar Ca+, fusion of cell membrane and synaptic vesicles
Term
2 types of Ach receptors
Definition
Muscarinic & Nicotinic
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