Term
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Definition
Neurotransmitter
-look at muscarinic agonists and antagonists to see function
Botulinum toxin- AChE release inhibitor |
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Term
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Definition
-SC or IM in emergencies
-low conc: b1+b2= bronchodilate, vasodilate. INC HR and SBP!
-high conc: a effect |
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Term
|
Definition
-a+b1 effect= INC SBP and DBP
can raise BP in severe shock |
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Term
|
Definition
INC BP
used in ER for hypotension due to shock (but danger of tachycardia because at high doses effect b1) |
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Term
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Definition
Indirect Sympathomimetics
*crosses BBB
*INC NE--> INC BP |
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Term
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Definition
Indirect Sympathomimetics- in some foods
-competitvely works again NE for for NET
-can inactivate MAO
SE: hypertensive crisis! |
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Term
|
Definition
Sympathetic Modulators
-slower and less potent effect as EPI
common use:
bronchodilator
eye exam (mydriasis)
nasal degongestant (OTC) |
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Term
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Definition
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Term
|
Definition
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Term
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Definition
α1 selective agonist
*INC DBP
*relieves nasal congestion |
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Term
|
Definition
α2 selective agonist
*hypertension
*Caution: abrupt withdrawal can cause Rebound HT!! |
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Term
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Definition
α2 selective agonist
-prodrug
-antihypertensive agent
*SAFE for pregnancy! |
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Term
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Definition
Nonselective beta receptor agonist
b1 and b2 agonist!
INC SBP, DEC DBP |
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Term
|
Definition
ß1 selective agonist (also α1)
-INC CO w/out reducing efficiency
-CHF |
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Term
| Albuterol, Metaproterenol, Terbutaline |
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Definition
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Term
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Definition
| Long-acting ß2 selective agonist |
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Term
|
Definition
smooth muscle contraction, vasoconsitriction
*α1 selective: Phenylephrine
*α2 selective:Clonidine, Alpha Methyldopa |
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Term
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Definition
-presynapic negative feedback
-posynaptic- inhibits insulin release from b-cells (islets) |
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Term
|
Definition
| postive chronotropic, ionotropic, and dromotropic |
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Term
|
Definition
| -bronchi, liver, and vasculature of skeletal muscle= dilates and relaxes |
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