Term
Class of drugs you see Lactic Acidosis and Hepatic Steatosis |
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Definition
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Term
Hyperpigmentation/skin discoloration |
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Definition
Emtricitabine (emtriva) (FTC) |
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Term
Fanconi Syndrome, Osteomalacia, DECREASED BMD |
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Definition
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Term
Should NOT use with Lamivudine (3TC) |
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Definition
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Term
Should NOT use with Emtricitabine (FTC) |
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Definition
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Term
Can cause acute HBV exacerbation in co-infected |
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Definition
Lamivudine, Emtricitabine, Tenofovir |
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Term
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Definition
Didanosine(ddl) and Abacavir (ABC) |
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Term
Only NRTI that is a problem in renal patients AND hepatic |
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Definition
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Term
MUST take this NRTI on an empty stomach unless you take with UTF |
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Definition
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Term
Do NOT use with Stavudine (d4t) |
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Definition
Didanosine (ddl) and Zidovudine (AZT) |
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Term
Do NOT use with didanosine or Zidovudine |
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Definition
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Term
Peripheral Neuropathy, Lipoatrophy, Insulin resistance/DM, Hyperlipidemia |
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Definition
Zidovudine (AZT), Stavudine (d4t), Didanosine (ddl) |
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Term
Can cause optic neuritis, NRTI |
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Definition
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Term
Bone marrow suppression, NRTI |
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Definition
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Term
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Definition
Etravirine (ETR), Rilpivirine |
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Term
Tablet can be dissolved in water NNRTI |
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Definition
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Term
Higher incidence of rash (SJS, TEN) and incidence of hepatotoxicity |
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Definition
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Term
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Definition
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Term
Should not really use in females with CD4 > 250 and Males with a CDF > 400 |
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Definition
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Term
INCREASED rate of virolgoic failures when HIV VL > 100,000 or CD4 < 200 |
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Definition
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Term
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Definition
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Term
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Definition
Stavudine (d4t), Zidovudine (ZDV) |
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Term
Teratogenic, avoid in women that are pregnant |
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Definition
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Term
NNRTI that should NOT be used with PPI without spacing it |
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Definition
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Term
Drug class has HIGHER genetic barrier to resistance than NNRTIs and INSTIs (need more virus mutation) |
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Definition
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Term
Drug class causes Fat maldistribution, INCRASED bleeding time in hemophiliacs, Dyslipidemia and issue problems |
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Definition
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Term
Indirect hyperbilirubinemia (jaundice or scleral icterus) |
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Definition
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Term
Space dosing when using acid suppressing agents , PI |
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Definition
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Term
Neprholithiasis, Cholelithiasis AND PR prolongation |
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Definition
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Term
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Definition
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Term
Preferred PI's for initial treatment |
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Definition
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Term
Contains Sulfonamide moiety |
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Definition
Darunavir (DRV), Tipranavir, Fosamprinavir (FPV) |
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Term
MUST NEVER be given without a booster (Ritonavir) |
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Definition
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Term
Can be given unboosted in ARV naive patients |
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Definition
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Term
PR and QT prolongation with Significant dyslipidemia (mainly TG) |
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Definition
Lopinavir/Ritonavir (kaletra) |
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Term
Can dissolve tablet in water (PI) |
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Definition
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Term
Cause significant diarrhea |
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Definition
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Term
Highest pill burden of PIs |
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Definition
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Term
Only PI that is NEVER boosted with Ritonavir (RTV) |
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Definition
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Term
Hepatotoxicity, drug induced hepatitis and Fatal/Non fatal intracranial hemorrhage |
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Definition
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Term
This class has fewer drug interactions than PI, NNRTI, MVC or EVG regimens |
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Definition
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Term
Potential for increase in Cr Kinase, myopathy and Rhabdomyolysis |
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Definition
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Term
Integrase inhibitor that requires food |
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Definition
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Term
Only recommended in patients with a baseline CrCl > 70 |
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Definition
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Term
Primarily only used in salvage therapy |
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Definition
Enfuvirtide (T-20) Fusion inhibitor |
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Term
Must be given Sub-Q dosing |
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Definition
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Term
Local injection site reaction in 100% of patients |
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Definition
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Term
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Definition
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Term
Can ONLY give in patients that have virus using CCR5 or R5 virus, can NOT be used in anything else even if mixed receptor virus |
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Definition
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