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ANG 107: Quiz 4_Miller
UC Davis
16
Biology
Undergraduate 4
10/20/2019

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Term
how selection influences a pop (assumin random mating) ==> chart
Definition
COMPLETELY RECESSIVE

S(A+A+) = 0
S(A+A) = SAA > 0

COMPLETELY DOMINANT
S(A+A+) = S(A+A) = 0
S(AA) > 0

NO DOMINANCE

S(A+A+) = 0
S(AA) = x>0
S(A+A) = 0.5x
Term
Mating system influence on allele and geno freq
Definition
* mating doesnt change allele freq, only changes was alleles are distrib
* does change genp distrib in a predictable way (depends if +/- assortive)
* mating system alone w/ no selection influences only geno freq, not allele

*selection changes the allele freq and geno b/c purging undesirable alleles
Term
How mating changes geno distrib
Definition
POSITIVE ASSORTATIVE MATING
* dec freq hetero
* inc freq homo


NEGATIVE ASSORTIVE
* inc freq hetero
* dec freq homo
Term
progeny testing
Definition
*try to lok at progeny of an ind to determine their geno

*necessary for an ind w/ a recessive allele that cant tell composition based on pheno
*proven w/ a tet cross
Term
test cross
Definition
*a cross designed to reveal the geno of an ind @ a locus of interaction
Term
Steps to perform progeny testing for a recessive allele
Definition
*testing progeny to determine if an ind is a carrier for an undesireable allele

1) ASSUME IND IS A CARRIER

2) DETERMINE P OF PRODUCING A HOMO RECESSIVE PROGENY FROM A SINGLE CROSS
*P(detection 1/ 1 progeny)

3) CALC P OF PROD @ LEAST 1 HOMO RECESSIVE PROGENY FROM X CROSSES
*P(detection w/ X progeny)

** if data doesnt support than you reject
Term
P (detection w/ x progeny)
Definition
* tells us if an ind was a carrier, there's a ___% chance of detecting the receessive allele over X amount of crosses

*quantifying our confidence
Term
Formula for detecting progeny
Definition
P(detect w/ x progeny) = 1 - P(no detecetion w/ x progeny) = 1 - P(no detect w/ 1 progeny)^x = 1 - P(detect w/ 1 progeny)


P(detect w/ x progeny) = 1 - [1 - P(detect w/ 1 progeny)]^x
Term
1 - [ 1 - P(detect w/ 1 progeny]^x
Definition
* for x, as you increase the P(detection for one cross), the fewer test crosses you have to set up for good confidence
Term
To detect the # of progeny needed
Definition
*use P(detect w/ 1 progeny)
*need ___ norm preg to have a 99% (given) P(@ least one being homo rec)
Term
Influencers of the P(detection)
Definition
1) # OF TEST CROSSES SET UP

2) P(DETECTION FROM 1 CROSS)
*depends on test cross
*w/ better test crosses --> inc P(detect)
Term
categorical trait
Definition
*a trait in which pheno are expressed in categories
* EX: coat color, salmon running time - fall/spring
Term
quantitative traits
Definition
*traits w/ cont distrib; most numerous trait
*a trait in which pheno show cont (numerical) expression
*EX: height, weight, MY, %pro/fat, lap time
Term
quantitative pheno distrib
Definition
*w/ lrger data sets, make bins/range smaller
Term
mendels laws and traits
Definition
*mendels laws apply to categorical
*mendels laws apply to quantitative if you look @ a single locus
-when using a PS, mendels laws predict the output: normal distrib where extreme values are less often than mod pheno values (mod pheno is more prevalent)
-e. ind gene behaves in a mendellian way, but when combined, they give a normal distrib
Term
blending
Definition
*inc # loci and/or env effects
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