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Anesthetic Pharm Ch 16
Chapter 16
26
Pharmacology
Graduate
09/06/2012

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Term
Halothane
Definition
highly potent, slow induction and recovery: used in peds due to lack of smell
Term
Halothane
Definition
Can cause severe hepatitis and necrosis
Term
Treatment of malignant hyperthermia
Definition
Dantrolene
Term
Dantrolene
Definition
Blocks Ca+ release from SR and stops tetany and heat production during Malignant hyperthermia
Term
Isoflurane and Enflurane
Definition
less potent than halothane but faster induction
Term
Enflurane
Definition
can cause seizures and renal toxicity
Term
Diethyl ether
Definition
higher blood gas than isoflurene but slow induction (NOT USED IN US)
Term
Nitrous Oxide
Definition
low oil/gas with rapid induction and recovery, impossible to reach needed partial pressure due to needed oxygen in preperation
Term
Nitrous oxide
Definition
AE: expanding pneumothorax, bowel air, middle ear obstruction, due to expansion of air cavities
Term
Desoflurane Sevoflurane
Definition
highly potent and rapid onset
Term
Desflurane
Definition
Larangeal spasm due to irritation of respiratory mucosa
Term
Propofol
Definition
IV infusion, rapid elimination
Term
Thiopental
Definition
ultrashort acting barbituate fast acting
Term
Thiopental
Definition
heart and lung depression also with laryngeal spasm, hemolytic anemia, and neuropathy
Term
Etomidate
Definition
can cause myoclonus
Term
Etomidate
Definition
binds between Alpha and beta untis of gaba receptor
Term
Ketamine
Definition
antagonist of NMDA receptor
Term
Ketamine
Definition
Hypertension, REsp depression, ICP elevation, hallucination
Term
Diazepam, Lorazepam
Definition
Agonist of gaba channels, increase freguency of firing
Term
Flumazenil
Definition
Diazepam/Lorazepam overdose tx
Term
Morphine/Fentanyl
Definition
agonist of mu-opioid receptor blocks neuro transmission
Term
Morphine/Fentanyl
Definition
nausea, vomit, constipation, cardia depression
Term
Naitrexone
Definition
Opioid overdose treatment
Term
Naitrexone
Definition
Opioid overdose treatment
Term
Succinylcholine
Definition
Induction of neuromuscular blockage thru nicotinic agonist continuous action
Term
Pancuronium, Tubocurarine
Definition
Induction of neuromuscular block by antagonist effects on nicotine receptors prevent depolarization
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