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Rotation 5 - Pre anesthetics
n/a
51
Veterinary Medicine
Undergraduate 3
02/17/2014

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Term
what is the definition of a pre-anesthetic
Definition
any drug administered within 1 hr of general anesthesia
Term
what are advantages of using a preanesthetic
Definition
-to facilitate restraint in excited or aggressive patients
-to minimize autonomic reflex activity such as salivation, bradycardia
-reduce the dose of the general anesthetic required for anesthesia
Term
what is the use of Anticholinergics?
Definition
-counteract vagal tone and will prevent bradycardia by "taking the brakes off the heart"
-prevent excessive secretion of the salivary glands
-reduces upper airway secretions
-reduce laryngospasm brought on by intubation
Term
why are Anticholinergics not used in horses?
Definition
it causes paralytic effects on the intestinal tract; may lead to colic
Term
what are specific drugs of Anticholinergics
Definition
atropine and glycopyrrolate
Term
why is glycopyrrolate more popular than atropine?
Definition
duration of action is twice that of atropine; less effect on the heart rate than atropine; will cause less elevation of the heart rate; less oxygen consumption by heart muscle; does not cross the placental barrier; no effect on the fetus at the time of C-section
Term
what is another name for glycopyrrolate?
Definition
Robinul
Term
what is the dose for glycopyrrolate?
Definition
.005 mg/pd SQ, IM, IV
Term
what is the dose for atropine?
Definition
dose 0.02mg/pd SQ/IM
Term
when is atropine recommended for use?
Definition
if heart rate is 140 or less
Term
what are 3 common tranquilizers?
Definition
acepromazine, valium and dexdormitor/rompun
Term
what kind of tranq is acepromazine?
Definition
phenothiazine derivative tranquilizer
Term
what does acepromazine protect against
Definition
epinephrine induced arrhythmias and ventricular tachycardia
Term
how does acepromazine work?
Definition
will suppress the activity of the sympathetic NS by blocking nerve receptors, neurotransmitter activity, alpha receptors, and dopamine receptors
Term
acepromazine can cause prolapse of what
Definition
3rd eyelid
Term
what does acepromazine cross and what happens because of it?
Definition
it crosses the placental barrier and will sedate newborns during a c-section
Term
acepromazine is counterindicate in cases of shock why?
Definition
will reduce the strength of contraction of the heart
Term
how is acepromazine metabolized
Definition
the liver
Term
why is acepromazine popular as a travel pill?
Definition
has anti-emetic properties
Term
what does acepromazine cause in horses?
Definition
penile paraylsis
Term
which tranq produces good, predictable sedation with wide margin of safety
Definition
acepromazine
Term
if hypotension occurs with ace, what can be done
Definition
IV fluids can be given
Term
why is ace avoided in pediatrics or geriatrics
Definition
prolonged duration of action
Term
acepromazine does what to the barbiturate it is used with?
Definition
cuts the dose in half; 4mg/pd as compared to 8mg/pd
Term
valium is also known as?
Definition
diazepam
Term
what kind of drug is valium
Definition
benzodiazepine compound
Term
is ace a controlled drug?
Definition
no
Term
is valium a controlled drug?
Definition
yes
Term
why is valium not given SQ
Definition
poorly absorbed
Term
what mg tabs is valium available in
Definition
2, 5, 10 mgs
Term
what are the effects of valium
Definition
sedative, muscle relaxant and anticonvulsant
Term
what are the analgesic effects of valium
Definition
minimal to no analgesic properties
Term
how is valium metabolized and how is it eliminated
Definition
liver; through bile and urine
Term
in what specific cases make valium a good choice?
Definition
epileptic patients and heart disease patients
Term
valium is used in place of what other tranq for older dogs and why?
Definition
acepromazine; has minimal cardiopulmonary depressing effects
Term
dose for valium
Definition
0.1 - 0.2 mg/lb IV or IM
Term
what is another name for xylazine?
Definition
rompun
Term
what is another name for Dexdomitor?
Definition
dexmedetomadine
Term
what is rompun reversed with?
Definition
yobine (yohimbine)
Term
what is dexdomitor reversed with?
Definition
antisedan (atipamezole)
Term
what kind of drugs are xylazine and dexodmitor?
Definition
-alpha-2 adrenergic agonist
-non-phenothiazine, non-narcotic drug
Term
what do alpha-2 adrenergic agonists cause?
Definition
initial vasoconstriction; causes mucus membranes to appear pale
Term
what effects do adrenergic agonists cause?
Definition
sedative, analgesic, muscle relaxant and hypnotic effects
Term
when using xylazine and dexdomitor, what happens to the requirements for maintenance of anesthesia with inhalation agents?
Definition
it is reduced by 50%
Term
what other anesthetic agents can be combined with xylazine or dexdormitor?
Definition
a. ketamine
b. Pentothal
c. halothane
d. isoflurane
Term
what drug(s) cause thermoregulation to be impaired post-op?
Definition
xylazine and dexdomitor
Term
what can happen if atropine is delivered after dexdomitor?
Definition
dangerous arrhythmias
Term
what tranqs are not common with veterinary anesthesiologists and why?
Definition
xylazine and dexdomitor; because of the effects on the heart
Term
what are the 4 popular narcotic drugs?
Definition
morphine, hydromorphone, fentanyl patch and torbugesic/buprenex
Term
narcotics are also known as
Definition
opiods
Term
What are the actions of pre-anesthetics on the autonomic nervous systems?
Definition
minimize autonomic reflex activity such as salivation & bradycardia
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