Term
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Definition
neutropenia, thrombocytopenia and pancytopenia |
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Term
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Definition
fatigue, dizziness, fainting, low blood pressure, palpitations, enlarged spleen, yellowing of eyes, skin paleness, coldness, SOB, muscle weakness, changed stool color |
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Term
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Definition
level of anemai (Hgb, Hct), rapidity of change, co-morbidities |
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Term
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Definition
mesh-like network of ribasomal RNA which becomes visible with methylene blue |
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Term
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Definition
mestrual blood loss, GI blood loss, pregnancy or poor iron absorption |
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Term
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Definition
insufficient intake of iron |
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Term
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Definition
blackstrap molasses, clams,raisin bran cereal, turkey (dark), red meat |
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Term
symptoms of B12 deficiency |
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Definition
yellow pallor, neuro-findings, sore-beefy tongue, anorexia, tachycardia, palpitations, cardiomyopathy, heart failure |
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Term
causes of folate deficiency |
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Definition
ETOH abuse, pregnancy, malabsorption/ inadequate intake and some drugs |
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Term
drugs causing folate deficiency |
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Definition
phenytoin, MTX and colchicine |
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Term
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Definition
dyspnea/fatigue, dark urine, pale/jaundice, enlarged spleen, tachycardia/murmers |
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Term
most patients have no evidence of hemolysis until an event |
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Definition
infection, drug reaction (sulfa, anti-malarials, ASA, INH, or eating a lot of fava beans |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
Mean corpuscular volume (MCV) |
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Definition
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Term
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Definition
Folate or B12 deficiency, chronic liver disease, chronic alcoholism, cytotoxic medications |
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Term
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Definition
Iron deficiency, alpha/beta thalassemia (minor) and chronic disease (usually normocytic) |
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Term
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Definition
Increased in central clear area |
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Term
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Definition
Iron deficient, anemia of chronic disease, alpha or beta thalassemia, decreased MCV |
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Term
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Definition
B12 deficient, folic acid deficient, alcoholism, some cytotoxic drugs, ususally increased MCV |
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Term
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Definition
Deformed broken cell, helmet cell, Burr cell, acanthpcyte, seen in mechanical valvular and hemolytic anemias |
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Term
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Definition
65% Hgb, 4% yoglobin, 30% ferritin, serum transferrin |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
Determines the ability to absorb B12 form the GI tract (requires intrinsic factor) |
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Term
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Definition
Suggests pernicious anemia |
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Term
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Definition
H2 antag, metformin, gastrectomy, poor dietary intake (limited meat and milk) |
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Term
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Definition
Looks like pernicious anemia but does not have neurologic symptoms |
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Term
Giving folic acid to pernicious anemia |
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Definition
Worsens neurologic symptoms |
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Term
Causes of folate deficiency |
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Definition
Alcoholism, preggers, phenytoin, colchicine, MTX, BCPs?, some small bowel diseases |
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Term
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Definition
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Term
DAT; Direct Coomb's (antiglobulin) test |
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Definition
Demonstrates presence of antibodies or complement on the surface of RBCs; hallmark of autoimmune hemolysis |
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Term
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Definition
Increased total bilirubin and unconjugated |
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Term
Normal total bilirubin levels |
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Definition
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Term
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Definition
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Term
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Definition
Used with suspected hemoglobinopathies and thalassimias |
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Term
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Definition
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Term
False positive guaiac test |
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Definition
Meat consumption and high dose vitamin C |
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Term
Myriad cause of pos guaiac test |
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Definition
Malignancy, Uv/diverticulitis, others |
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