Term
| What are the three divisions of the CNS during development? |
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Definition
| Prosencephalon, mesencephalon, rhombencephalon |
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Term
| What are the two divisions of the prosencephalon? |
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Definition
| Telencephalon, diencephalon |
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Term
| What are the three divisions of the telencephalon? |
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Definition
| cerebral hemispheres, basal ganglia, basal forebrain |
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Term
| What are the three divisions of the diencephalon? |
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Definition
| Thalamus, hypothalamus, epithalamus |
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Term
| What are the two features of the mesencephalon? |
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Definition
| Cerebral peduncles, midbrain aqueduct |
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Term
| What are the two divisions of the rhombencephalon? |
|
Definition
| Metencephalon, myelencephalon |
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Term
| What are the two components of the metencephalon? |
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Definition
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Term
| What is the primary feature of the myelencephalon? |
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Definition
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Term
| From which spinal nerves does the sympathetic NS arise? |
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Definition
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Term
| From which nerves does the parasympathetic NS arise? |
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Definition
| Cranial nerves III, VII, IX and X; S2-S4 |
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Term
| What is the primary function of microglia? |
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Definition
| specialized macrophages for phagocytosis |
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Term
| What are the different macroglia cell types? |
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Definition
| Radial glia, astrocytes, oligodendrocytes, ependyma, Schwann cells |
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Term
| What is the primary function of radial glia? |
|
Definition
| Neurodevelopment; neuronal progenitors and scaffold upon which neurons migrate and find their proper place |
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|
Term
| What is the primary function of astrocytes? |
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Definition
| Regulate chemical environment; recycle neurotransmitters |
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|
Term
| What is the primary function of oligodendrocytes? |
|
Definition
|
|
Term
| What is the primary function of ependymal cells? |
|
Definition
| Line the ventricles & secrete CSF |
|
|
Term
| What is the primary function of Schwann cells? |
|
Definition
|
|
Term
| What is the approximate ratio of glia:neurons in the cortex? |
|
Definition
|
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Term
| True or false: chemical synapses are associated with a coupling potential |
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Definition
| False; this phenomenon is associated w/ electrical synapses |
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|
Term
| Which neurotransmitter is the primary excitatory NT? |
|
Definition
|
|
Term
| Which neurotransmitter is the primary inhibitory NT? |
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Definition
|
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Term
| What is the primary function of metabotropic postsynaptic receptors? |
|
Definition
| Activate second-messenger systems |
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Term
| What are some drugs that block Na+ channels? |
|
Definition
Local anesthetics, e.g. lidocaine
(Class Ia, Ib, Ic)
Pufferfish tetrodotoxin (TTX) |
|
|
Term
| What are some drugs that block K+ channels? |
|
Definition
4-aminopyridine (4-AP), tetraethylammonium chloride (TEA)
(Class III) |
|
|
Term
| What is the MOA of curare? |
|
Definition
Blocks nicotinic ACh receptors -> muscle relaxation
Antidote = acetylcholinesterase inhibitor (e.g. neostigmine) |
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Term
| What affect on the NS does triethyl tin have? |
|
Definition
| Intra myelin split intoxication- forms focal swellings in the CNS myelin; PNS not affected |
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|
Term
| Are heavy metals (e.g. Ba, Cs, etc) more toxic to the CNS or PNS? |
|
Definition
|
|
Term
| What is allergic encephalomyelitis? |
|
Definition
| Central demylelination caused by antibodies against central basic protein |
|
|
Term
| What is allergic neuritis? |
|
Definition
| Peripheral demyelination caused by antibodies against peripheral basic protein |
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|
Term
| Where are GABAc receptors located? |
|
Definition
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