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Anatomy & Physiology Exam 3
Synapse Type & Transmission of Signals
19
Anatomy
Undergraduate 2
04/13/2010

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Term
what is a synapse? what are the types?
Definition
-the junction where information is transferred in 1 of 3 ways:
1) from 1 neuron to another (neuro-neuronal)
2) from a neuron to a muscle (neuro-muscular)
3) from a neuron to a gland (neuro-glandular)
Term
what way of synapse transfer is from a neuron to a gland?
Definition
-neuro-glandular
Term
what is the presynaptic cell?
Definition
-the neuron SENDING the signal
Term
what is the postsynaptic cell?
Definition
-the structure RECEIVING the signal
Term
what are the two signals involved in neuron transmission?
Definition
1) presynaptic cell (neuron SENDING the signal)
2) postsynaptic cell (structure RECEIVING the signal)
Term
what are the 2 functional types of synapses?
Definition
1) electrical synapse: cells are joined by specialized cellular adhesions (gap junctions)
2) chemical synapse: specialized for release and reception of neurotransmitters
Term
what type of functional synapse is more common?
Definition
chemical synapse
Term
what are gap junctions?
function?
where found?
Definition
-specialized cellular adhesions in electrical synapses
-allow electricity to flow very quickly from cell to cell
-ex: heart
Term
what are neurotransmitters?
Definition
-released and received in chemical synapses
-convert electrical signals into chemical signals
Term
how do neurotransmitters convert electrical signals into chemical signals?
Definition
-the chemical signal travels across the synapse to the post-synaptic structure
-then it is converted back into an electrical signal
Term
what are the factors that tell whether the postsynaptic structure can be excited or inhibited?
Definition
-neurotransmitter
-receptor
-type of ion channel that receptor is associated with
Term
what is excitatory postsynaptic potential? (EPSP)
Definition
-a neurotransmitter binding to its receptor causes ion channels that allow depolarization to open
-membrane becomes more positive on the inside and is brought closer to threshold
-mostly associated with chemically-gated sodium channels
Term
in EPSP (excitatory postsynaptic potential) what causes ion channels that allow depolarization to open?
Definition
-a neurotransmitter binding to its receptor
Term
what charge does the inside of the membrane become during EPSP? where does it go?
Definition
-membrane becomes more positive on the inside
-brought closer to threshold
Term
which channel is excitatory postsynaptic potential mainly associated with?
Definition
-chemically-gated sodium channels
Term
what is inhibitory postsynaptic potential? (IPSP)
Definition
-a neurotransmitter binding to its receptor causes ion channels that allow hyperpolarization to open
-membrane becomes more negative inside and is taken further away from threshold
-mainly associated with chemically-gated potassium channels (w/ potassium efflux) OR chemically-gated chloride channels (w/ chloride influx).
Term
what does a neurotransmitter binding to its receptor cause in IPSP?
Definition
-causes ion channels that allow hyperpolarization to open
Term
what charge is the inside of the membrane with an IPSP?
-where is it taken?
Definition
-more negative on the inside
-further from threshold
Term
which channel is inhibitory postsynaptic potential mainly associated with?
Definition
-chemically-gated potassium channels (with potassium efflux)
-chemically-gated chloride channels (with chloride influx)
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