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Anatomy and Physiology II
Immune System Chapter 21
5
Anatomy
Undergraduate 2
09/03/2012

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Term
Innate (Nonspecific) Defenses
Definition
Species Resistance
First line of defense
Mechanical Barriers
Second line of defense
Chemical Barriers
Natural Killer (NK) Cells
Inflammation
Phagocytosis
Fever
Term
Adaptive Immune Response
Definition
3rd Line of Defense
Humoral (antibody mediated) immunity
Stimulates secretion of antibodies by B cells
Cell-mediated immunity
T cells (helper, cytotoxic, & suppressor)
T helper cells
Bind specialized antigen presenting cells, like B cells or macrophage
Activate and direct other immune cells
Cytotoxic T cells
Binds all cells and destroy infected cells
Term
Adaptive Immune Response
Definition
Aspects of the Adaptive Immune Response
Specific
Systemic
Memory
Primary vs. secondary responses
Term
Autoimmunity
Definition
When immune attacks self
Type I diabetes, Rheumatoid arthritis, Lupus, MS
Term
Hypersensitivities
Definition
Allergies
Result of the immune system causing tissue damage as it fights off a perceived threat that would otherwise be harmless
Immediate hypersensitivities
1st meeting no reaction, becomes sensitized
Start in seconds
Anaphylatic shock
Subacute hypersensitivities
Antibody-mediated
Start in 1-3 hours
Delayed hypersensitivity reactions
Cell-mediated
Start in 1-3 days, lingers
Allergic contact dermatitis
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