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synthesis and decomposition reactions |
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catalytic proteins; works on substrate; not used up; like a lock and key |
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number of molecules per second the enzyme can handle |
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where the substrate fits into the enzyme |
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where regulatory molecules attach to regulate activity of the enzyme |
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molecules that must attach to the enzyme to make it work; often ions |
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usually not proteins, referred to as vitamins |
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What factors control rates of reactions? |
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substrate concentration (higher, faster) enzyme concentration (higher, faster) pH (specific) temperature (higher, faster) |
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temperature at which the enzyme is denatured and the reaction is stopped |
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chemical that causes denaturation of enzymes |
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A-->B-->C-->D...(P) every enzyme is critical |
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cellular respiration (oxygen used) forms ATP |
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ATP (adenosine triphosphate) |
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Definition
5 carbon sugar nitrogen base 3 phosphate groups |
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C6H12O6 + 6O2 --> 6CO2 + 6H2O + energy (38 ATP) |
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glycolysis Kreb's cycle electron transport chain |
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10 steps Embden-Myerhoff pathway only anaerobic organisms can live on just this process 2 pyruvates (2 ATP, 1 ACoA each) 1 ACoA --> 1 NADH2 |
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uses 5 NADH2 and 1 FADH2 19 ATP total per pyruvate 38 per glucose molecule |
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group of cells that function together for a specific purpose |
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covers surfaces and body cavities very thin to get oxygen self-renewing avascular (no blood vessels) |
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diffusion and filtration kidneys, blood capillary walls, air sacs in lungs |
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protection mouth, nasal cavity, skin may have other types underneath |
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secretion/absorption gland surfaces |
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strengthens walls of ducts sweat glands, salivary glands |
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passageways may have microvilli in passageway (may absorb/secrete)(cilia move mucus) respiratory |
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rare in humans male urethra, female mammary gland |
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vascular cells widely spaced (matrix materials) provide support for organs bind body parts together protection and storage |
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large, flat, star-shaped collagen |
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crawl around, engulf bacteria or cellular debris |
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heparin (keep blood from coagulating) histamines/histones (cause blood vessels to dilate) |
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areolar tissue matrix contains large amounts of interstitial fluid |
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interstitial fluid contains... |
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interstitial fluid: white, resistant to pulling, flexible |
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interstitial fluid: yellow, elastic |
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interstitial fluid: lots of branches, proteins, give softness and flexibility to tissue |
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stores excess fats ("signet ring" cells) modified fibroblasts subcutaneous layer, insulates body women have thicker layer |
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collagenous matrix: dense network of collagen fibroblasts silvery white tendons, ligaments |
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elastic connective tissue |
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Definition
yellowish because of elastin fibers chondrocytes walls of lungs, urinary bladder, large arteries |
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matrix: dense network of collagen and elastin chondrocytes and fibroblasts strength and flexibility between joints, branches of respiratory system, vertebral column, nose, ears |
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types of connective tissues |
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loose adipose dense elastic cartilage bone blood |
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capable of contraction function: movement, posture, heat production |
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muscles attached to bones striated voluntary control cells are long and cylindrical length of muscle, multinucleated, fast response, short refractory period |
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alternating dark and light bands on muscles |
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period of time before muscle relaxes after contracting |
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held in contracted state by sending nerve impulses |
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walls of hollow internal organs (stomach, bladder, uterus) smooth muscle (unstriated) involuntary cells are spindle shaped single nucleus, slower response, long refractory period, can still go into tetanus contraction |
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only in walls of the heart striated involuntary doesn't need nerve impulses to contract cells are rectangular, single nucleus, intercalated disks between cells slow response long refractory period, can not go into tetanic contraction |
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types of nervous tissue cells |
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Definition
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excitable cells carry nerve impulses "functional units" |
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nonexcitable cells support and protect nervous tissue |
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brain, spinal cord regulate, control, and coordinate throughout the body |
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mediators of inflammation chemical substances that release symptoms of inflammation |
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abnormal accumulation of fluid beneath skin or in a cavity that produces swelling |
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thick, yellowish-white fluid, excess fluids, dead blood cells |
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Definition
replacing dead or damaged cells with new ones |
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important for tissue repair |
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nutrition blood circulation age |
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new cells are the same type as destroyed cells (parenchymal cells) "perfect healing" very shallow, not past epidermis |
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new type of cell replaces dead cells scar tissue ALWAYS formed fibroblasts usually some loss of function very deep, past epidermis |
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epithelial membranes NOT cell membranes 2 layers: epithelial above connective tissue |
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serous mucous synovial cutaneous |
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line internal body cavities secrete _____ fluid lubricate surfaces minimize friction |
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secrete _____ various passageways have an opening to the external of the body thicker than serous fluid |
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form inner lining of joint cavities secretes _____ fluid lubricates bones at the joint |
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skin/integument covers outer surface of body |
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consists of skin and structures derived from skin (hair, nails, skin glands) skin is the largest organ of the body (10% of body weight in the avg adult) is 0.5mm-5mm thick, most of body is 1-2 mm thick |
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protection against water loss, microbial invasion, harmful UV rays maintain temperature homeostasis (37-38 C, heat loss, sweat) vitamin D synthesis (requires sunlight) excretes sweat keratin melanocytes |
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Definition
protein with water-proofing abilities, difficult for bacteria to get in |
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Definition
secretes the chemical melanin to absorb UV radiation |
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structures of integumentary system |
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Definition
epidermis dermis adapose tissue |
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Term
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Definition
epithelial tissue outermost stratified 4-5 layers |
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Definition
stratum basale stratum spinosum stratum granulosum (stratum lucidum) stratum corneum |
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bottom layer of epidermis aka stratum germinativum continually renewing epidermis |
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prickly appearance because keratin is being produced directly above stratum basale |
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granular appearance because keratin is being packed directly above stratum spinosum |
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translucent only found in palms and soles packed with eleidin directly above stratum granulosum |
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Definition
hardened, dead cells continually being replaced topmost layer of epidermis |
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produced in stratum basale found only in bottom two layers of epidermis protects body from UV radiation |
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large amounts of matrix materials (collagen and elastin) |
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region of dermis pili hold in place contains blood vessels and nerve receptors |
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reticulin makes skin soft receptors give sensation to pressure |
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structures derived from skin |
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Definition
hair sebaceous glands sweat glands nails |
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protection contained in follicle arrector pili muscles - "goosebumps" composed of dead epidermal cells flat scale-like, more keratin |
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Definition
bundles of smooth muscle that contract to pull the hair up straight "goosebumps" |
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one for each hair follicle secrete sebum into follicle prevents hair from drying out and being brittle has antibacterial properties |
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suderiferous glands eccrine apocrine contains water, salt, and some waste material brain sends messages |
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coil tube deep in dermis most numerous in forehead, back, palms, and soles |
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groin and armpit areas comes up the hair inactive until puberty characteristic odors for sexual attraction; active during sexual arousal |
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composed of dead cells heavily keratinized grow about 1 mm/wk on fingers, toes are slower protects ends of fingers and toes aid in grasping small objects (needles, etc) |
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temperature is too high enzymes will denature |
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temperature is too low processes will slow and lead to organ and heart failure |
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skeletal muscles and heart are main sources dermal vasodilation suderiferous glands (sweat) dermal vasoconstriction skeletal muscles (shivering) |
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causes blood vessels to dilate, promoting heat loss |
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less blood flow to keep heat in |
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radiation (infrared) conduction convection evaporation |
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warmer to cooler from surfaces |
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warmer to cooler from cold air |
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evaporation (as heat loss) |
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the only method in which surroundings are warmer than our bodies sweat |
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released by white blood cells causes setting in hypothalamus to rise (fever) |
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heat, radiation, electrical, chemical 1st degree (least harmful) 2nd degree 3rd degree (most harmful) |
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epidermal layers only localized effects "superficial partial thickness" burns |
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epidermal and dermal damage some cells still alive, rapid regeneration can occur blisters always form scarring may occur "deep partial thickness" burns |
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epidermis and dermis destroyed "full thickness" burns slow regeneration disfiguring/disabling scars always form dead cells need to be removed body fluids need to be replaced wounds may be covered with grafts or skin substitutes very painful |
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affects parts of body far from burns plasma and plasma proteins lost (shock) bacteria can get in and spread more susceptible to bacterial infections blood circulation reduced reduce urine production to retain water |
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result from bacterial, viral or yeast infections some are genetic some the source is unknown skin cancers are common acne carbuncles cold sores psoriasis skin cancers |
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inflammatory disease of sebaceous glands begins at puberty overactive sebaceous gland gets plugged and debris forms (blackhead) cyst forms from infection, pinching can cause permanent scars |
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severe compound boils spreads down into subcutaneous layer most commonly due to bacterial infection |
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small, itchy, fluid-filled blisters mostly around lips caused by virus herpes simplex (remains dormant until activated by stress or a cold) contagious once active never really leaves |
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chronic reddened patches on skin with silvery scales scalp, back, elbows, knees too much mitotic activity may be hereditary triggered by trauma/emotional stress |
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overexposure to harmful UV radiation takes long time to appear basal cell carcinoma squamous cell carcinoma malignant melanoma |
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least deadly, most common skin cancer cells no longer produce keratin spreads into dermis starts as shiny, dome-shaped nodule on surface, very slow growing easily cured by surgical removal |
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skin cancer in stratum spinosum scaly red elevation on surface of skin causes shallow depression, looks like a sore grows more rapidly spreads to lymph nodes and elsewhere removed surgically can kill you if ignored |
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only 6% of all skin cancers begins with a melanocyte that has been altered appears as round black patch on skin resembles a mole except for rough edges and mixture of colors spreads rapidly |
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