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Anatomy and Physiology Exam 3
Exam 3 powerpoints
36
Anatomy
Undergraduate 1
11/08/2010

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Term
Principles of Muscle Mechanics
Definition
1. same principles apply to contraction of a single fiber and a whole muscle
2. Contraction produces tension, the force exerted on the load or object to be moved
3. Contraction doesn't always shorten a muscle
4. force of duration of contraction vary in response to stimuli of different frequencies and intensities
Term
Motor Unit
Definition
motor neuron and all (four to several hundred) muscle fibers it supplies
Term
Small motor units
Definition
muscles that control fine movements (fingers, eyes)
Term
Large motor units
Definition
large weight-bearing muscles (thighs, hips)
Term
Muscle fibers from a motor unit
Definition
are spread throughout the muscle so that a single motor unit that causes weak contraction of entire muscle
Term
motor units in a muscle
Definition
usually contract asynchronously; helps prevent fatigue
Term
Muscle Twitch
Definition
Response of a muscle to a single, brief threshold stimulus
Term
Three phases of a twitch
Definition
Latent period, Period of contraction, and period of relaxation
Term
First stage of a twitch: Latent Period
Definition
events of excitation-contraction coupling
Term
Second stage of a twitch: Period of contraction
Definition
cross bridge formation; tension increases
Term
Third stage of a twitch: Period of relaxation
Definition
CA2+ reentry into the SR; tension declines to zero
Term
Muscle twitch comparisons
Definition
Different strength and duration of twitches are due to variations in metabolic properties and enzymes between muscles
Term
Graded muscle responses
Definition
Variations in the degree of muscle contraction, Required for proper control of skeletal movement
Responses are graded by changing the frequency of stimulation, and changing the strength of the stimulus
Term
Response to change in stimulus frequency
Definition
a single stimulus results in a single contractile response- a muscle twitch, increase frequency of stimulus, Ca2+ release stimulates further contraction->temporal (wave) summation, Further increase in stimulus frequency->unfused (incomplete) tetanus
Term
Threshold stimulus
Definition
stimulus strength at which the first observable muscle contraction occurs
Term
Muscle contracts more vigorously as stimulus strength is
Definition
increases above threshold
Term
Contraction force
Definition
is precisely controlled by recruitment(multiple motor unit summation), which brings more and more muscle fibers into action
Term
Size principle
Definition
motor units with larger and larger fibers are recruited as stimulus intensity increases
Term
Muscle Tone
Definition
Constant, slightly contracted state of all muscles, due to spinal reflexes that activate groups of motor units alternately in response to input from stretch receptors in muscles, keeps muscles firm, healthy, and ready to respond
Term
Isotonic Contractions
Definition
Muscle changes in length and moves the load, either concentric or eccentric
Term
Isometric contractions
Definition
the load is greater than the tension the muscle is able to develop, tension increases to the muscle's capacity, but the muscle neither shortens nor lengthens
Term
Available stores of ATP are depleted in
Definition
4-6 seconds
Term
ATP is regenerated by
Definition
Direct phosphorylation of ADP by creatine phosphate, Anaerobic pathway (glycolysis), and aerobic respiration
Term
Anaerobic Pathway
Definition
At 70% of maximum contractile activity; bulging muscles compress blood vessels, oxygen delivery is impaired, pyruvic acid is converted into lactic acid
Term
Lactic acid
Definition
diffuses into the bloodstream, used as fuel by the liver, kidneys, and heart, and is converted back into pyruvic acid by the liver
Term
Aerobic Pathway
Definition
produces 95% of ATP during rest and light to moderate excercise, Fuels-> stored glycogen, then bloodborne glucose, pyruvic acid from glycolysis, and free fatty acids
Term
Muscle Fatigue
Definition
Physiological inability to contract, occurs when Ionic imbalances interfere with E-C coupling, and prolonged excercise damages the SR and interferes with Ca2+ regulation and release
Term
Oxygen Defecit
Definition
Extra O2 needed after exercise for replenishment of: oxygen reserves, glycogen stores, and ATP and CP reserves. also for conversion of lactic acid to pyruvic acid, glucose, and glycogen
Term
Heat Production during muscle activity
Definition
~40% of the energy released in muscle activity is useful as work, remaining energy (60%) is given off as heat, and Dangerous heat levels are prevented by radiation of heat from skin and sweating
Term
The force of contraction is affected by:
Definition
Number of muscle fibers stimulated (recruitment) and relative size of the fibers- hypertrophy of cells increases strength, increased frequency allows time for more effective transfer of tension to noncontractile components
Term
velocity and duration of contraction is influenced by:
Definition
muscle fiber type (slow oxidative fibers, fast oxidative fibers, fast glycolytic fibers), load, and recruitment
Term
muscle fiber type
Definition
classified by: speed of contraction: slow or fast, according to: speed at which myosin ATPases split ATP and pattern of electrical activity of the motor neurons, and also by the metabolic pathways for ATP synthesis: oxidative fibers-use aerobic pathways, and glycolytic fibers use anaerobic glycolysis
Term
Influence of load
Definition
the greater the load, the greater the latent period, slower contraction, and decreased duration of contraction
Term
Influence of Recruitment
Definition
the more motor units that are contracting, the faster contraction and more prolonged the contraction
Term
Aerobic (endurance) exercise
Definition
leads to increased:
muscle capillaries, number of mitochondria, and myoglobin synthesis
results in greater endurance, strength, and resistance to fatigue
may convert fast glycolytic fibers into fast oxidative fibers
Term
Overload principle
Definition
forcing a muscle to work hard promotes increased muscle strength and endurance, muscles adapt to increased demands, and muscles must be overloaded to produce further gains
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