Term
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Definition
the largest gland in the body weighing at 3 lbs, it has serosa extept at the bare area. The diaphragm and the liver are connected. |
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Term
The liver has both exocrine and endocrine properties. It's functions include: |
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Definition
1. Making bile
2. Making blood proteins (Albumin)
3. Store Excess glucose as glycogen
4. Store fat soluble vitamins like A
5. Primary organ of drug metabolism |
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Term
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Definition
is right next to the gallbladder |
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Term
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Definition
is the entry way to the liver, containing the hepatic artery (carrying O2 rich blood to the liver), the Hepatic portal vein (carrying things absorbed from intestines), and the left hepatic duct which transports bile. |
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Term
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Definition
the smallest section of the liver, at its 6 corners it has portal triads and portal tracts. Has a central vein at its center, with hepatocytes branching off. |
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Term
The portal triad contains... |
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Definition
a branch of the bile duct, a branch of the hepatic portal vein, and a branch of the hepatic artery. |
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Term
The parenchymal cell is the... |
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Definition
main cell of the liver, making up 80% of it |
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Term
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Definition
large leaky capillaries between the hepatocytes, lined by discontinuous endothelium. They have a mixing of arterial and vein blood. |
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Term
What are the organelle concentrations in hepatocytes and what is their function? |
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Definition
High SER to make (Exocrine), High RER and Golgi to make albumin (endocrine), High SER and Peroxisomes and abundant mitochondria to aid in fat storage and drug metabolism. |
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Term
Describe the flow of nutrients in the hepatocytes |
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Definition
Bile enters the bile canalculus, blood protein and glucose enters the sunisoid, and nutrients and toxins enter the hepatic cell. |
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Term
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Definition
the macrophage of the Liver |
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Term
The Stroma of the liver... |
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Definition
is the supporting tissue that is reticular CT. |
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Term
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Definition
stores and concentrates bile |
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Term
Can you live without a gallbladder? |
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Definition
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Term
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Definition
muscles around the gallbladder contract, extreting it's extra bile into duodenum |
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Term
What 3 things dump into the duodenum? |
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Definition
Chyme, Bile, and Pancreatic enzymes |
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Term
The Acinar cells in the pancreas are |
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Definition
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Term
Inactive form of enzymes in the pancreas are stored in... |
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Definition
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Term
Saliva is composed of _________________________________ and it functions to ______________ |
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Definition
H2O, ions, mucus, ENZ, and bicarbonate;
Moistens mouth, binds food, making bolus |
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Term
The enzyme in saliva ____________ and bicarbonate ________________ |
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Definition
starts starch digestion;
Neutralizes acid from bacteria |
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Term
What are the types of glands in the mouth |
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Definition
Parotid - Purely Serous
Submandibular - Mucus and Serous
Sublingual - Mucus and Serous |
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Term
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Definition
Serous secretion - watery, ions, ENZ
Mucous secretion - thick mucus |
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Term
Glands in the tongue are.... |
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Definition
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Term
What are the basic organs of the respiratory system? |
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Definition
Nose, oral cavity, Larynx, the Bronchii, the pharynx, the trachea, and the lungs |
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Term
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Definition
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Term
Right lung has _ lobes, and left lung has _ lobes |
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Definition
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Term
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Definition
1. Passage way for air
2. Contitions air (warm, moisten, clean)
3. Involved in phonation |
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Term
Conducting vs respiratory zones |
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Definition
Conducting zone- No gas exchange, a passage way that conditions air by cleaning, moistening and warming it. anything not listed below.
Respiratory zone - Gas exchange is possible, alveoli are present. Respiratory bronchiole, alveolar duct, alveolar sac, and alveoli. |
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Term
the Nasal Vestibule is... |
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Definition
the part of the inside of the nose that has hair and sweat glands |
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Term
Describe the nasal cavities properties |
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Definition
1. Has olfactory mucosa - limited to superior concha housing olfactory epithelium
2. Respiratory mucosa - epithelium and lamina propria, pseudostratified ciliated columnar epithelium and goblet cell. |
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Term
The lamina propria in the respiratory tract... |
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Definition
contains seromucous glands that moisten the air, alot of capillaries and veins used to warm the air |
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Term
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Definition
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Term
The parts of the pharynx are... |
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Definition
Nasopharynx (respiratory mucosa), the oropharynx (stratified squamous), and the laryngopharynx (stratified squamous) |
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Term
Soft pallette serves to... |
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Definition
prevent food from entering the nasal area |
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Term
Describe the 2 folds in the trachea |
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Definition
the vestibular fold, and the vocal fold which holds vocal ligaments |
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Term
The larynx has _ named cartilages |
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Definition
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Term
The 3 functions of the larynx: |
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Definition
1. Voice production
2. Passage way
3. Switching mechanism between air and food |
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Term
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Definition
1. Epiglottis
2. Cuniform cartilages
3. Corniculate cartilages
4. Arytenoid cartilages (start of vocal cords)
5. Cricoid cartilages
6. Tracheal cartilages
7. thyroid cartilage (end of vocal cords) |
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Term
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Definition
the opening between the true vocal cords |
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Term
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Definition
has 16-20 c shaped hyaline cartilage rings with fibroelastic CT between C cartilage. It has 4 layers
1.Mucous membrane
2. Submucosa
3. Hyaline cartilage
4. Advantitia |
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Term
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Definition
controls diameter of the lumen of the trachea and connects between the hyaline cartilages |
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Term
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Definition
Mams=primary bronchi, 1/lung
Lobar=secondary bronchi 1/lobe
Segmental=tertiary bronchi 1/segment
bronchiole<1mm, no cartilage
Terminal bronchiole<0.5mm |
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Term
Changes from in bronchial tree: |
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Definition
Decrease in cartilage, decrease in height of epithelium (pseudostratified columnar, simple columnar to cuboidal), increase in elastic fibers, increase in smooth muscle |
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Term
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Definition
respiratory bronchioles, alveolar duct, and alveolar sac |
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Term
________ branch off the sides of the alveolar duct, and at the end there are __________ |
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Definition
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Term
A type 1 pneumocyte is... |
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Definition
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Term
On the outside of all the alveoli are... |
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Definition
capilaries and elastic fibers |
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Term
The type 1 pneumocyte, the fused basal lamina and the endothelium of the capilary comprise the _______________ |
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Definition
Blood-air barrier AKA the repsiratory membrane |
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Term
The type II pneumocyte performs what functions? |
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Definition
1. Stem Cell
2. Produces surfactant (reduces surface tension, coats inner surface of the alveolus) |
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Term
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Definition
a macrophage that cleans the alveolus, also known as PAM (pulmonary alveolar macrophage) |
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Term
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Definition
allows for equilibrium of air, and allows for alternate routes for air to flow |
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Term
Lymphatic vessels - think... |
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Definition
Transport lymph
and return lymph to veins in base of neck |
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Term
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Definition
provides immunity, long term resistance |
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Term
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Definition
Lymph duct, lymph trunk, lymph node, lymphatic collecting vessels with valves, lymphatic capillaries |
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Term
Lymph is a _ way flowing system |
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Definition
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Term
Tissue fluid contains ______________, and what moves into the lymphatic capillaries is called ______ |
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Definition
H2O, blood proteins, cells, pathogens, bacteria, cancer cells, etc.; Lymph |
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Term
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Definition
remove the components of tissue fluid that aren't wanted |
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Term
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Definition
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Term
How does tissue fluid enter the capillaries? |
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Definition
The endothelium has callogen fibers which connect to the local tissue, when it swells, it causes the valve to open, allowing tissue fluid in, until swelling goes down when it closes. |
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Term
Collecting vessels, lymph trunk, and lymph duct are structured like... |
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Definition
Blood vessels, in that they have the same 3 layers |
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Term
Tunica intima is composed of... |
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Definition
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Term
Tunica media is composed of- |
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Definition
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Term
lymphnodes are located... |
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Definition
in the path of collecting vessels |
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Term
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Definition
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Term
The intestinal trunk and the lumbar trunk form... |
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Definition
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Term
the thoracic duct returns lymph from... |
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Definition
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Term
The beginning of the thoracic duct is the... |
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Definition
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Term
Thoracic duct dumps its lymph betwen |
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Definition
the subclavian vein and the jugular vein |
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Term
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Definition
Parenchymal cell= lymphocyte
Stroma= reticular CT (except in thymus)
Cells= B lymphocyte and T lymphocyte, plasma cells, macrophages
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Term
B. lymphocyte vs T lymphocyte
(when exposed to antigen) |
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Definition
B lymphocyte converts to a plasma cell, which produces antibodies to attach antigens. Memory cells (lymphocytes on reserve) ready to respond to 2nd exposure. Humoral immunity.
T lymphocytes has memory cells as well. I has helper cells, and cytotoxic cells. They respond to antigens on cell membranes, respond to eukaryotic cells (cancer, virally infected, fungal, transplanted cells). Cell mediated immunity. |
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Term
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Definition
antigen presenting cells, and phagocytosis |
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Term
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Definition
highly concentrated area of lymphocytes, just B cells |
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Term
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Definition
Indicates an immune response, |
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Term
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Definition
MALT (mucosa associated lymphoid tissue) |
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Term
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Definition
Leukocytes, agranulocytes |
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Term
All lymphocytes originate from... |
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Definition
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Term
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Definition
thymus to become immunocompetent. They have the ability to recognize foreign material. |
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Term
B cells do what to become immunocompetent? |
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Definition
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Term
The organs in the lympoid system are.. |
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Definition
the tonsils, the thymus, the spleen, the aggregated lymphoid nodules and the appendix |
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Term
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Definition
has cortex & medula, B+T cells, stroma is reticular CT, functions to remove pathogens, cancer cells.... from lymph. ~500 exist |
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Term
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Definition
Has a cortex and medulla, No B cells only T cells, Stroma is epithelial reticular cells, only lymphoid organ that does not mount an immune response, has a blood-thymus barrier. It functions as the site where T cells become immunocompetent. |
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Term
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Definition
No cortex & medulla but has red pulp and white pulp, has B & T cells, stroma is reticular CT.
Red pulp removes damaged or dead RBC's.
White pulp removes blood-borne pathogens, and has the immune function |
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Term
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Definition
No cortex & medulla, contains B & T cells, Stroma is reticular CT, located in the mucosa of pharynx. Only lymphoid organ that is covered by an epithelium. |
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Term
What can you survive without? |
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Definition
A few lymphs (concentrated removal is bad)
thymus can be removed but life is tricky since there are no T cells
Spleen can be removed
Tonsils can be removed |
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Term
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Definition
a channel for lymph, lined by endothelium |
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Term
Lymphnode trabeculae are... |
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Definition
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Term
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Definition
B & T cells (extension of cortex), macrophages and plasma cells |
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Term
Afferent vs efferent lymphatic vessels |
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Definition
Flow goes from afferent to efferent vessels |
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Term
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Definition
a point where structures enter or exit or both |
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Term
What is the only WBC that can re-circulate? |
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Definition
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Term
As you get older the thymus goes through the process of __________ which is when... |
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Definition
involution: thymic tissue is mostly replaced by adipose |
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Term
The function of the lymphnode is... |
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Definition
to remove pathogens from the lymph |
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Term
Medulary cords are cellular, containing... |
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Definition
B&T cells, macrophages and plasma cells |
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Term
Degenerative epithelial-reticular cells are found in the _________ of the thymus and are called _________ |
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Definition
medulla; Thymic (Hassall's) corpuscles |
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Term
The hormones in the thymus... |
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Definition
allow the T cells to become immunocompetent |
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Term
White pulp in the spleen... |
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Definition
is made of PALS and of lymphoid tissue |
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Term
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Definition
Pariarterial lymphatic sheath, which are the sleeve of T cells/B cells |
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Term
The spleen has a _______ capsule, because it is... |
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Definition
thick; very bloody, and rupturing could cause one to bleed out |
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Term
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Definition
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Term
Once the splenic artery leaves the connective tissue and enters the matter of the spleen, it is called... |
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Definition
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Term
The central artery may not appear to be _________ because of B cell __________ |
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Definition
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Term
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Definition
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Term
The venous sinuses of red pulp contain ____ |
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Definition
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Term
Cords in Red pulp mainly contain... |
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Definition
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Term
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Definition
in the mucosa of the pharynx |
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Term
the 2 sets of tonsils are... |
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Definition
the pharyngeal (pseudostratified ciliated epithelium) and the palatine (stratified squamous non-keratinized) |
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Term
Which kidney is more superior than the other? Why? |
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Definition
the left kidney due to the liver blocking the other kidney |
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Term
What 4 things surround/protect the kidneys? |
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Definition
1. fibrous capsule
2. Perirenal fat capsule
3. The anterior and posterior renal fascia
4. Pararenal fat |
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Term
What is the function of the kidney? |
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Definition
It filters blood conserving H2O, ions, A.A's, and glucose, while it secretes wastes (urea, uricacid) drug metabolites, ions, H2O
It forms concentrated urine |
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Term
What is unusual about the kidney's medula? |
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Definition
it is in the shape of pyramids |
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Term
The region where the renal cotrex is between the medullar pyramids is called... |
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Definition
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Term
Kidneys have ______ lobes, which consist of.... |
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Definition
7-11; medullary pyramid and associated cortical tissue |
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Term
What is the path of blood through the kidney? |
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Definition
Renal artery to segmental artery to lobar artery to interlobar artery, to arcuate artery to interlobular artery |
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Term
What is the functional unit of the kidney? How many are there? What does it consist of? |
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Definition
the nephron; 1million; Renal corpuscle and tubular portion |
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Term
The renal corpuscle is the site of... |
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Definition
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Term
the tubular portion is the site of... |
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Definition
reabsorption and secretion |
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Term
The uriniferous tubule consists of... |
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Definition
the nephron and the collecting ducts |
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Term
Renal corpuscle consists of... |
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Definition
the glomerulus and the bowman's capsule |
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Term
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Definition
a tuft of capillariers, fenestrated |
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Term
the bowman's capsule is composed of... |
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Definition
simple squamous epithelium comprising the parietal layer (outside) and the visceral layer (hugs the glomerulus) |
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Term
The capsular space (AKA urinary space)... |
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Definition
is the space between the visceral and parietal layers of the bowman's capsule |
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Term
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Definition
small pores in capillaries that are small enough to not allow cells through but fluids |
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Term
The layers of the podocyte are... |
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Definition
1. The fenestrated capillary endothelium
2. The basement membrane
3. The filtration slits |
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Term
The molecular barrier functions to... |
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Definition
blocks material due to charge and or size |
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Term
After the bowman's capsule comes the... |
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Definition
proximal convoluted tubule P.C.T. |
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Term
proximal convoluted tubule P.C.T. is composed of_____________________ and it's function is... |
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Definition
simple cuboidal epithelium, microvilli, and mitochondria;
reabsoprtion and secretion |
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Term
What are the parts and functions of the loop of henle? |
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Definition
Thick descending limb, functions like the PCT
The thin limb, functions to concentrate the urine
Thick ascending limb, functions like the DCT |
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Term
describe the distal convoluted tubule (aka DCT) |
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Definition
shorter than the PCT, it's simple cuboidal epithelium and has selective ion secretion (Potassium), and selective ion reabsorption (NCl), it has fewer microvilli and mitochondria than the PCT |
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Term
The collecting duct serves as... |
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Definition
the kidney's last chance to reabsorb water |
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Term
ADH and aldosterone serve to... |
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Definition
Anti diuretic hormone effects the collecting duct, and aldosterone (from the zona glomerulosa of the renal cortex) causes an increase of Na+ reabsorbtion in the DCT |
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Term
Cortical nephrons vs juxtamedullary nephrons |
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Definition
Cortical- 85% of nephrons, almost entirely located in the cortex, the thin segment of the loop of henle is extremely small
Juxtamedullary- 15% of nephrons, they have the longest thin limbs of henle that concentrate the urine |
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Term
from the efferent arteriol arises |
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Definition
the eritubular capillaries |
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Term
materials reabsorbed via tubules are colected in __________. Waste materials to be secreted by the kidneys are delivered via _____________ |
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Definition
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Term
The capillaries associated with the justamedullary nephron are... |
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Definition
the vasa recta, they arise from the efferent arteriol |
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Term
The juxtaglomerular apparatus functions to ________ and is composed of... |
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Definition
regulate BP; the macula densa and the granular cells (AKA JG cells) |
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Term
describe JG cells (granular) |
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Definition
The are modified sm. muscle cells of the afferent arteriole, they contain granules with renin and detect change in blood volume. Decrease in blood volume causes them to release renin, to increase the release of aldosterone, and causes an increase in Na+ absorption and H2O absorbtion. Increasing blood volume and BP. |
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Term
Describe the macula densa |
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Definition
modified regtion of DCT, they detect the concentration of Na+ in the blood. If there is a decrease in Na+, they tell the JG cells to release renin |
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Term
Describe the path of Urine. What epithelium lines each? |
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Definition
1. Minor Calyx (1/lobe)
2. Major calyx (2~3)
3. Renal Pelvis (most superior part of ureter)
4. Ureter
5. Urinary Bladder
6. Urethra
1-5 are lined with transitional, 6 is lined with tansitional and others. |
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Term
What are the layers of the ureter and urinary bladder? |
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Definition
1. Mucosa (transitional epithelium, lamina propria)
2. Muscularis (Upper 2/3's has 2 layers, lower 1/3 and urinary bladder has 3)
3. Advantitia
*serosa is on the most superior part of the urinary bladder |
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Term
What are the muscularis layers in the urinary track? |
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Definition
1. Inner longitudinal
2. Middle Circular
3. Outer longitudinal in the lower 3rd |
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Term
Describe the flow of urine from the urinary bladder |
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Definition
1. Urinary bladder
2.internal urethral sphincter
3.External urethral sphincter
4.urogenital diaphragm
5.Spongy urethra |
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