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Anatomy and Histology Quiz 6
Study for A&H at ONU
141
Biology
Undergraduate 1
04/24/2009

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Term
The liver is...
Definition
the largest gland in the body weighing at 3 lbs, it has serosa extept at the bare area.  The diaphragm and the liver are connected.
Term
The liver has both exocrine and endocrine properties.  It's functions include:
Definition

1. Making bile

2. Making blood proteins (Albumin)

3. Store Excess glucose as glycogen

4. Store fat soluble vitamins like A

5. Primary organ of drug metabolism

Term
The quadrate lobe...
Definition
is right next to the gallbladder
Term
The porta hepatis...
Definition
is the entry way to the liver, containing the hepatic artery (carrying O2 rich blood to the liver), the Hepatic portal vein (carrying things absorbed from intestines), and the left hepatic duct which transports bile.
Term
The lobule is...
Definition
the smallest section of the liver, at its 6 corners it has portal triads and portal tracts.  Has a central vein at its center, with hepatocytes branching off.
Term
The portal triad contains...
Definition
a branch of the bile duct, a branch of the hepatic portal vein, and a branch of the hepatic artery.
Term
The parenchymal cell is the...
Definition
main cell of the liver, making up 80% of it
Term
Sinusoids are...
Definition
large leaky capillaries between the hepatocytes, lined by discontinuous endothelium.  They have a mixing of arterial and vein blood.
Term
What are the organelle concentrations in hepatocytes and what is their function?
Definition
High SER to make (Exocrine), High RER and Golgi to make albumin (endocrine), High SER and Peroxisomes and abundant mitochondria to aid in fat storage and drug metabolism.
Term
Describe the flow of nutrients in the hepatocytes
Definition
Bile enters the bile canalculus, blood protein and glucose enters the sunisoid, and nutrients and toxins enter the hepatic cell.
Term
The Rapffer Cell is...
Definition
the macrophage of the Liver
Term
The Stroma of the liver...
Definition
is the supporting tissue that is reticular CT.
Term
The gallbladder...
Definition
stores and concentrates bile
Term
Can you live without a gallbladder?
Definition
Yes
Term
When fat is consumed...
Definition
muscles around the gallbladder contract, extreting it's extra bile into duodenum
Term
What 3 things dump into the duodenum?
Definition
Chyme, Bile, and Pancreatic enzymes
Term
The Acinar cells in the pancreas are
Definition
Exocrine
Term
Inactive form of enzymes in the pancreas are stored in...
Definition
zymogen granules
Term
Saliva is composed of _________________________________ and it functions to ______________
Definition

H2O, ions, mucus, ENZ, and bicarbonate;

 

Moistens mouth, binds food, making bolus

Term
The enzyme in saliva ____________ and bicarbonate ________________
Definition

starts starch digestion;

 

Neutralizes acid from bacteria

Term
What are the types of glands in the mouth
Definition

Parotid - Purely Serous

 

Submandibular - Mucus and Serous

 

Sublingual - Mucus and Serous

Term
Serous vs Mucus gland
Definition

Serous secretion - watery, ions, ENZ

 

Mucous secretion - thick mucus

Term
Glands in the tongue are....
Definition
Compound tubuloaveolar
Term
What are the basic organs of the respiratory system?
Definition
Nose, oral cavity, Larynx, the Bronchii, the pharynx, the trachea, and the lungs
Term
The alveolus is...
Definition
the site of gas exchange
Term
Right lung has _ lobes, and left lung has _ lobes
Definition
3; 2
Term
Functions of the nose
Definition

1. Passage way for air

 

2. Contitions air (warm, moisten, clean)

 

3. Involved in phonation

Term
Conducting vs respiratory zones
Definition

Conducting zone- No gas exchange, a passage way that conditions air by cleaning, moistening and warming it.  anything not listed  below.

 

Respiratory zone - Gas exchange is possible, alveoli are present.  Respiratory bronchiole, alveolar duct, alveolar sac, and alveoli.

Term
the Nasal Vestibule is...
Definition
 the part of the inside of the nose that has hair and sweat glands
Term
Describe the nasal cavities properties
Definition

1. Has olfactory mucosa - limited to superior concha housing olfactory epithelium

 

2. Respiratory mucosa - epithelium and lamina propria, pseudostratified ciliated columnar epithelium and goblet cell.

Term
The lamina propria in the respiratory tract...
Definition
contains seromucous glands that moisten the air, alot of capillaries and veins used to warm the air
Term
Paranasal sinuses...
Definition
condition the air
Term
The parts of the pharynx are...
Definition
Nasopharynx (respiratory mucosa), the oropharynx (stratified squamous), and the laryngopharynx (stratified squamous)
Term
Soft pallette serves to...
Definition
prevent food from entering the nasal area
Term
Describe the 2 folds in the trachea
Definition
the vestibular fold, and the vocal fold which holds vocal ligaments
Term
The larynx has _ named cartilages
Definition
9
Term
The 3 functions of the larynx:
Definition

1. Voice production

 

2. Passage way

 

3. Switching mechanism between air and food

Term
The 9 cartillages:
Definition

1. Epiglottis

2. Cuniform cartilages

3. Corniculate cartilages

4. Arytenoid cartilages (start of vocal cords)

5. Cricoid cartilages

6. Tracheal cartilages

7. thyroid cartilage (end of vocal cords)

Term
The Rima glottidis is...
Definition
the opening between the true vocal cords
Term
The trachea
Definition

has 16-20 c shaped hyaline cartilage rings with fibroelastic CT between C cartilage. It has 4 layers

 

1.Mucous membrane

2. Submucosa

3. Hyaline cartilage

4. Advantitia

Term
The trachealis muscle...
Definition
controls diameter of the lumen of the trachea and connects between the hyaline cartilages
Term
The bronchial tree:
Definition

Mams=primary bronchi, 1/lung

Lobar=secondary bronchi 1/lobe

Segmental=tertiary bronchi 1/segment

bronchiole<1mm, no cartilage

Terminal bronchiole<0.5mm

Term
Changes from in bronchial tree:
Definition
Decrease in cartilage, decrease in height of epithelium (pseudostratified columnar, simple columnar to cuboidal), increase in elastic fibers, increase in smooth muscle
Term
Respiratory zone:
Definition
respiratory bronchioles, alveolar duct, and alveolar sac
Term
________ branch off the sides of the alveolar duct, and at the end there are __________
Definition
alveoli; alveolar sac
Term
A type 1 pneumocyte is...
Definition
the alveolus
Term
On the outside of all the alveoli are...
Definition
capilaries and elastic fibers
Term
The type 1 pneumocyte, the fused basal lamina and the endothelium of the capilary comprise the _______________
Definition
Blood-air barrier AKA the repsiratory membrane
Term
The type II pneumocyte performs what functions?
Definition

1. Stem Cell

2. Produces surfactant (reduces surface tension, coats inner surface of the alveolus)

Term
A dust cell is...
Definition
a macrophage that cleans the alveolus, also known as PAM (pulmonary alveolar macrophage)
Term
Alveolar pores...
Definition
allows for equilibrium of air, and allows for alternate routes for air to flow
Term
Lymphatic vessels - think...
Definition

Transport lymph

and return lymph to veins in base of neck

Term
immune - think...
Definition
provides immunity, long term resistance
Term
Do the lymph heirarchy.
Definition
Lymph duct, lymph trunk, lymph node, lymphatic collecting vessels with valves, lymphatic capillaries
Term
Lymph is a _ way flowing system
Definition
1
Term
Tissue fluid contains ______________, and what moves into the lymphatic capillaries is called ______
Definition
H2O, blood proteins, cells, pathogens, bacteria, cancer cells, etc.; Lymph
Term
Lymph nodes serve to...
Definition
remove the components of tissue fluid that aren't wanted
Term
Lacteal-
Definition
lymph capillary
Term
How does tissue fluid enter the capillaries?
Definition
The endothelium has callogen fibers which connect to the local tissue, when it swells, it causes the valve to open, allowing tissue fluid in, until swelling goes down when it closes.
Term
Collecting vessels, lymph trunk, and lymph duct are structured like...
Definition
Blood vessels, in that they have the same 3 layers
Term
Tunica intima is composed of...
Definition
endothelium and LCT
Term
Tunica media is composed of-
Definition
sm muscle
Term
lymphnodes are located...
Definition
in the path of collecting vessels
Term
Valves serve to do what?
Definition
prevent backflow
Term
The intestinal trunk and the lumbar trunk form...
Definition
the Thoracic duct
Term
the thoracic duct returns lymph from...
Definition
3/4ths of the body
Term
The beginning of the thoracic duct is the...
Definition
cisterna chyli
Term
Thoracic duct dumps its lymph betwen
Definition
the subclavian vein and the jugular vein
Term
describe lymphoid tissue
Definition

Parenchymal cell= lymphocyte

Stroma= reticular CT (except in thymus)

Cells= B lymphocyte and T lymphocyte, plasma cells, macrophages

 

Term

B. lymphocyte vs T lymphocyte

(when exposed to antigen)

Definition

B lymphocyte converts to a plasma cell, which produces antibodies to attach antigens.  Memory cells (lymphocytes on reserve) ready to respond to 2nd exposure. Humoral immunity.

 

T lymphocytes has memory cells as well.  I has helper cells, and cytotoxic cells.  They respond to antigens on cell membranes, respond to eukaryotic cells (cancer, virally infected, fungal, transplanted cells). Cell mediated immunity.

Term
Macrophages serve as...
Definition
antigen presenting cells, and phagocytosis
Term
lymphoid follicle/nodule
Definition
highly concentrated area of lymphocytes, just B cells
Term
Germinal center
Definition
Indicates an immune response,
Term
Mucosa=
Definition
MALT (mucosa associated lymphoid tissue)
Term
B +T cells are..
Definition
Leukocytes, agranulocytes
Term
All lymphocytes originate from...
Definition
the red bone marrow
Term
T cells migrate to the
Definition
thymus to become immunocompetent.  They have the ability to recognize foreign material.
Term
B cells do what to become immunocompetent?
Definition
stay in the bone marrow
Term
The organs in the lympoid system are..
Definition
the tonsils, the thymus, the spleen, the aggregated lymphoid nodules and the appendix
Term
Describe the Lymph nodes
Definition
has cortex & medula, B+T cells, stroma is reticular CT, functions to remove pathogens, cancer cells.... from lymph. ~500 exist
Term
Describe the Thymus
Definition
Has a cortex and medulla, No B cells only T cells, Stroma is epithelial reticular cells, only lymphoid organ that does not mount an immune response, has a blood-thymus barrier.  It functions as the site where T cells become immunocompetent.
Term
Describe the spleen
Definition

No cortex & medulla but has red pulp and white pulp, has B & T cells, stroma is reticular CT.

 

Red pulp removes damaged or dead RBC's.

 

White pulp removes blood-borne pathogens, and has the immune function

Term
Describe the tonsils
Definition
No cortex & medulla, contains B & T cells, Stroma is reticular CT, located in the mucosa of pharynx.  Only lymphoid organ that is covered by an epithelium.
Term
What can you survive without?
Definition

A few lymphs (concentrated removal is bad)

 

thymus can be removed but life is tricky since there are no T cells

 

Spleen can be removed

 

Tonsils can be removed

Term
Lymph node sinus is...
Definition
a channel for lymph, lined by endothelium
Term
Lymphnode trabeculae are...
Definition
extensions of DCT
Term
Lymphnode cords are...
Definition
B & T cells (extension of cortex), macrophages and plasma cells
Term
Afferent vs efferent lymphatic vessels
Definition
Flow goes from afferent to efferent vessels
Term
Hilum is..
Definition
a point where structures enter or exit or both
Term
What is the only WBC that can re-circulate?
Definition
Lymphocytes
Term
As you get older the thymus goes through the process of __________ which is when...
Definition
involution: thymic tissue is mostly replaced by adipose
Term
The function of the lymphnode is...
Definition
to remove pathogens from the lymph
Term
Medulary cords are cellular, containing...
Definition
B&T cells, macrophages and plasma cells
Term
Degenerative epithelial-reticular cells are found in the _________ of the thymus and are called _________
Definition
medulla; Thymic (Hassall's) corpuscles
Term
The hormones in the thymus...
Definition
allow the T cells to become immunocompetent
Term
White pulp in the spleen...
Definition
is made of PALS and of lymphoid tissue
Term
PALS are...
Definition
Pariarterial lymphatic sheath, which are the sleeve of T cells/B cells
Term
The spleen has a _______ capsule, because it is...
Definition
thick; very bloody, and rupturing could cause one to bleed out
Term
Trabecula in the spleen
Definition
guide the blood
Term
Once the splenic artery leaves the connective tissue and enters the matter of the spleen, it is called...
Definition
the Central artery
Term
The central artery may not appear to be _________ because of B cell __________
Definition
center; proliferation
Term
Red pulp is made of...
Definition
venous sinuses and cords
Term
The venous sinuses of red pulp contain ____
Definition
blood
Term
Cords in Red pulp mainly contain...
Definition
macrophages
Term
The tonsil is located...
Definition
in the mucosa of the pharynx
Term
the 2 sets of tonsils are...
Definition
the pharyngeal (pseudostratified ciliated epithelium) and the palatine (stratified squamous non-keratinized)
Term
Which kidney is more superior than the other? Why?
Definition
the left kidney due to the liver blocking the other kidney
Term
What 4 things surround/protect the kidneys?
Definition

1. fibrous capsule

2. Perirenal fat capsule

3. The anterior and posterior renal fascia

4. Pararenal fat

Term
What is the function of the kidney?
Definition

It filters blood conserving H2O, ions, A.A's, and glucose, while it secretes wastes (urea, uricacid) drug metabolites, ions, H2O

 

It forms concentrated urine

Term
What is unusual about the kidney's medula?
Definition
it is in the shape of pyramids
Term
The region where the renal cotrex is between the medullar pyramids is called...
Definition
the renal columns
Term
Kidneys have ______ lobes, which consist of....
Definition
7-11; medullary pyramid and associated cortical tissue
Term
What is the path of blood through the kidney?
Definition
Renal artery to segmental artery to lobar artery to interlobar artery, to arcuate artery to interlobular artery
Term
What is the functional unit of the kidney? How many are there? What does it consist of?
Definition
the nephron; 1million; Renal corpuscle and tubular portion
Term
The renal corpuscle is the site of...
Definition
blood filtration
Term
the tubular portion is the site of...
Definition
reabsorption and secretion
Term
The uriniferous tubule consists of...
Definition
the nephron and the collecting ducts
Term
Renal corpuscle consists of...
Definition
the glomerulus and the bowman's capsule
Term
The glomerulus is...
Definition
a tuft of capillariers, fenestrated
Term
the bowman's capsule is composed of...
Definition
simple squamous epithelium comprising the parietal layer (outside) and the visceral layer (hugs the glomerulus)
Term
The capsular space (AKA urinary space)...
Definition
is the space between the visceral and parietal layers of the bowman's capsule
Term
Fenestrations are...
Definition
small pores in capillaries that are small enough to not allow cells through but fluids
Term
The layers of the podocyte are...
Definition

1. The fenestrated capillary endothelium

2. The basement membrane

3. The filtration slits

Term
The molecular barrier functions to...
Definition
blocks material due to charge and or size
Term
After the bowman's capsule comes the...
Definition
proximal convoluted tubule P.C.T.
Term
proximal convoluted tubule P.C.T. is composed of_____________________ and it's function is...
Definition

simple cuboidal epithelium, microvilli, and mitochondria;

 

reabsoprtion and secretion

Term
What are the parts and functions of the loop of henle?
Definition

Thick descending limb, functions like the PCT

 

The thin limb, functions to concentrate the urine

 

Thick ascending limb, functions like the DCT

Term
describe the distal convoluted tubule (aka DCT)
Definition
shorter than the PCT, it's simple cuboidal epithelium and has selective ion secretion (Potassium), and selective ion reabsorption (NCl), it has fewer microvilli and mitochondria than the PCT
Term
The collecting duct serves as...
Definition
the kidney's last chance to reabsorb water
Term
ADH and aldosterone serve to...
Definition
Anti diuretic hormone effects the collecting duct, and aldosterone (from the zona glomerulosa of the renal cortex) causes an increase of Na+ reabsorbtion in the DCT
Term
Cortical nephrons vs juxtamedullary nephrons
Definition

Cortical- 85% of nephrons, almost entirely located in the cortex, the thin segment of the loop of henle is extremely small

 

Juxtamedullary- 15% of nephrons, they have the longest thin limbs of henle that concentrate the urine

Term
from the efferent arteriol arises
Definition
the eritubular capillaries
Term
materials reabsorbed via tubules are colected in __________. Waste materials to be secreted by the kidneys are delivered via _____________
Definition
peritubular capillaries
Term
The capillaries associated with the justamedullary nephron are...
Definition
the vasa recta, they arise from the efferent arteriol
Term
The juxtaglomerular apparatus functions to ________ and is composed of...
Definition
regulate BP; the macula densa and the granular cells (AKA JG cells)
Term
describe JG cells (granular)
Definition
The are modified sm. muscle cells of the afferent arteriole, they contain granules with renin and detect change in blood volume.  Decrease in blood volume causes them to release renin, to increase the release of aldosterone, and causes an increase in Na+ absorption and H2O absorbtion.  Increasing blood volume and BP.
Term
Describe the macula densa
Definition
modified regtion of DCT, they detect the concentration of Na+ in the blood.  If there is a decrease in Na+, they tell the JG cells to release renin
Term
Describe the path of Urine.  What epithelium lines each?
Definition

1. Minor Calyx (1/lobe)

2. Major calyx (2~3)

3. Renal Pelvis (most superior part of ureter)

4. Ureter

5. Urinary Bladder

6. Urethra

 

1-5 are lined with transitional, 6 is lined with tansitional and others.

Term
What are the layers of the ureter and urinary bladder?
Definition

1. Mucosa (transitional epithelium, lamina propria)

2. Muscularis (Upper 2/3's has 2 layers, lower 1/3 and urinary bladder has 3)

3. Advantitia

*serosa is on the most superior part of the urinary bladder

Term
What are the muscularis layers in the urinary track?
Definition

1. Inner longitudinal

2. Middle Circular

3. Outer longitudinal in the lower 3rd

Term
Describe the flow of urine from the urinary bladder
Definition

1. Urinary bladder

2.internal urethral sphincter

3.External urethral sphincter

4.urogenital diaphragm

5.Spongy urethra

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