Term
anatomy and histology are... |
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Definition
the study of gross anatomy (large structures that are visible with the naked eye, and require dissection) and microscopic anatomy (requires microscope to view smaller structures such as cells tissues and organs) respectively |
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Term
define morphology and how it is related to anatomy |
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Definition
morphology is the study of form, and is synonymous with anatomy |
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Term
What are the two ways of studying gross anatomy? |
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Definition
Systemic (skeletal, muscular, etc) vs regional (head, abdomen, etc) |
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Term
What is the anatomical position? |
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Definition
Standing straight, toes forward, palms outward |
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Term
What are the basic regions of the body, and what do they encompass? |
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Definition
axial: head, neck, thorax, abdomen, pelvis and perineum and appendicular=limbs, including girdles (attachments of appendages) |
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Term
What are the Cephalic body areas? |
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Definition
Frontal, orbital, nasal, oral and mental |
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Term
What are the three planes of the body? |
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Definition
Transverse, sagital and frontal (coronal) |
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Term
descrive the transverse cut |
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Definition
A horizontal cut, dividing superior and inferior (upper and lower) regions of the body |
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Term
Describe the sagital plane, differentiate between the midsagital and parasagital cuts |
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Definition
Sagital separates left from right the midsagital section is a cut directly down the midline, while parasagital is an off midline cut |
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Term
Describe the frontal (coronal) plane |
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Definition
Vertical separation of anterior (ventral) and posterior (dorsal) regions of the body. Separates front from back. |
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Term
Superior means..... while inferior means.... |
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Definition
Toward the head/above; away from head/below |
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Term
Anterior means... while posterior means... |
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Definition
towards the front of the body/ventral; towards the back of the body/dorsal |
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Term
proximal means... while distal means... |
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Definition
At or near point of origin/attachment; away from point of origin/attachment |
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Term
superficial means... while deep means... |
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Definition
towards the surface of the body; towards the core |
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Term
medial means.... while lateral means... |
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Definition
at/near/toward the midline; away from the midline |
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Term
Ipsilateral means... contralateral means.... and are terms mainly used in reference to the ____ system |
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Definition
on the same side; on the opposite side; nervous |
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Term
What are the basic body cavities? |
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Definition
the dorsal and the ventral body cavities |
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Term
what is contained in the dorsal cavity? |
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Definition
the brain and the spinal cord |
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Term
what is contained in the ventral cavity? which are serous cavities? |
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Definition
the thoracic cavity (containing pleural cavities and the pericardial cavities which are all serous) the abdominopelvic cavity (containing the abdominal cavity (holds digestive viscera) and the pelvic cavity(holds repro and urinary viscera)) which is also known as the peritoneal serous cavity |
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Term
viscera is defined as.... |
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Definition
any organ located in the ventral body cavity |
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Term
What are the membranes in the ventral body cavity called? What do they produce, and what is it's purpose? |
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Definition
Serous membranes which produce serous fluid, allowing viscera to move without friction |
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Term
What are the two types of serous membranes, and what do they cover? |
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Definition
the visceral serous membrane, which covers the outer surfaces of visceral organs in the ventral body cavity; and the parietal serous membranes, which line the walls of the ventral body cavity |
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Term
What is the serous cavity, and what does it contain? |
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Definition
the space between the two visceral membranes which contains serous fluid |
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Term
What are the parts of the peritoneal serous cavity? |
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Definition
The parietal (peritoneal serous membrane) and visceral (peritoneal serous membrane) parts |
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Term
What are the visceral and parietal pleura? |
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Definition
The two membranes surrounding the lungs, and lining the walls around the lungs (respectively) |
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Term
What are the 9 abdominal regions? |
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Definition
Right Hypochondriac, epigastric, Left Hypochondriac, left lumbar, umbiblical, left lumbar, right iliac (inguinal region), hypogastric, and left iliac regions |
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Term
What is the costal cartillege? |
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Definition
the cartillege that attaches the ribs and false ribs to the sternum |
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Term
pain in the lower right quadrant could be... |
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Definition
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Term
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Definition
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Term
What are the three microscopes used in histology, what are their abreviations and uses? |
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Definition
Light Microscope (LM) which is used to view larger microscopic structures, and provides true color. EX Cell,tissue, organs, some organelles Transmission Electron Microscopes (TEM) which is used to study smaller more specific parts of microscopic structures called ultrastructure. EX. Organelles Scanning Electron Microscope (SEM), which is used to see surface detail, and provides a 3-D image |
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Term
Describe the steps in specimen preparation |
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Definition
1. Fixation - preserve specimen to prevent postmortem change 2. Embed - providing a support around the specimen (I.E. Wax) 3. Section - slice specimen thin enough to allow light/electrons to pass through 4. Stain - Allows specimen to be visualized |
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Term
How does Staining for Light Microscopy work? What are the types of dye, and what is an example of each? |
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Definition
Dyes are charged, and therefore bind to tissue components of opposite charge. Basic dye has a positive charge, Hematoxylin is a blue basic dye. Acidic dye has a negative charge, Eosin is a pink acidic dye. |
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Term
What things are dyed by Hematoxylin? What color would they be? |
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Definition
Nucleus, nucleolus, Ribosomes, Rough Endoplasmic Reticulum (RER) and DnA/RnA |
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Term
What things are dyed by Eosin, and what color would they be? |
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Definition
Cytoplasm, Mitochondria, Smooth Endoplasmic Reticulum (SER), and callogen fibers |
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Term
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Definition
a minor distrotion introduced during processing/preparation |
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Term
What is an anatomical anomoly? |
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Definition
It is a variation in a specimen from the normal, such as a blood vessel which has a different origin or location. Some Anatomical anomolies don't support life, such as missing an important organ like the heart. |
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Term
What is used in the staining process for Electro Microscopy? |
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Definition
Heavy metals which retard electrons |
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Term
What are x-rays (radiographs) useful for? |
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Definition
Viewing dense hard tissue (such as bone) |
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Term
What is the order of the anatomical Heirarchy? |
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Definition
Atoms --> Macromolecules --> cells --> tissue --> organs --> organ systems --> organism |
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Term
What is the cell membrane called, what is it made of, and what is it's function? |
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Definition
plama lemma, it is composed of the phospholipid bilayer, proteins, and oligosacharides It acts as a boundary between the internal cell environment and the external environment. It also determines what materials enter and exit the cell via diffusion, facilitated transport, endocytosis, and exocytosis. |
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Term
what important molecular structure does the nucleus contain? |
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Definition
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Term
What is an anucleate, and what is an example? |
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Definition
A cell with no nucleus, Mature Red Blood Cells are anucleate |
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Term
What is multinucleate? Give an example |
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Definition
A cell with more than one nucleus, skeletal muscle is an example of a multinucleate |
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Term
What is the endoplasmic reticulum? name the two in the cell |
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Definition
a network of interconnecting tube or sacs made of membranes The rough endoplasmic reticulum and the smooth endoplasmic reticulum |
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Term
What is the function of the Rough Endoplasmic Reticulum (RER)? |
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Definition
It is involved in protien and membrane synthesis, and has many ribosomes. |
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Term
What is the function of the Smooth Endoplasmic Reticulum (SER)? |
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Definition
It is a lipid membrane inolved in drug metabolism, it as no ribosomes |
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Term
What is the function of the mitochondria? what does a high concentration of mitochondria indicate? what color does it stain? |
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Definition
It is the site of ATP synthesis, many indicate a cell that uses alot of energy, and it stains pink (meaning it has a + charge) |
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Term
What is the Golgi (aparatus/body)? |
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Definition
It is a stack of membranes that are not connected, which recieve material from RER (via transport vesicle), modify the package material, and determine it's final destination. |
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Term
what is the difference between free and attached ribosomes? |
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Definition
free ribosomes produce proteins to be used within the cell, while attached protiens (which are embedded in the RER) are used to make proteins for export. |
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Term
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Definition
it is a vesicle which contains hydrolytic enzymes used to digest certain things within the cell. |
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Term
Secretory granule's are used for... |
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Definition
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Term
Vesicles from the golgi may be incorporated into the cell, how? |
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Definition
by incorporating the vesicle into the cell membrane |
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Term
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Definition
vesicles that contain oxidative enzymes and catalase and are used for digestion of certain materials. |
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Term
What is the function of the nucleolus? How many can a cell have? |
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Definition
It is the site of synthesis of ribosomal sub units. The cell will have as many as are necessary to it's functioning. |
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Term
What is the function of the nucleus? |
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Definition
it houses chromatin (DNA and protein) |
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Term
What is Heterochromatin? How does it appear on slides? |
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Definition
Heterochromatin is condensed chromatin that cannot be transcribed. It stains darkly |
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Term
What is Euchromatin? How does it appear on a slide? |
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Definition
It is a relaxed chromatin which is easily transcribed. It appears to be clear or lightly stained since it is not condensed like heterochromatin |
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Term
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Definition
also known as actin, it is used in cytokinesis and allows cellular movement |
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Term
what is intermediate filament? What is their special use? |
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Definition
it provides tensile strength to resist pulling forces within the cell. They are used diagnostically to determine the source of a cancer, due to their stability. |
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Term
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Definition
it is a filament of the cytoskeleton that determines the shape of the cell, and are used to move material already inside the cell. |
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Term
what are the components of the cytoskeleton? which are stable? |
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Definition
Microfilaments, which are not stable (constant turnover) intermediate filaments which are extremely stable Microtubules which are not stable (constant turnover) |
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Term
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Definition
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Term
What are the 4 basic tissue types? |
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Definition
Epithelium (epithelial tissue) Connective tissue Muscle Tissue Nervous Tissue |
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Term
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Definition
Sheets of cells that cover the body surfaces and line body cavities and line hollow organs. It sits on the basal lamina (which is acellular) between 2 different environments (one is connective tissue, the side with the changing environment is where the epithelial cells are located) |
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Term
What are some of the functions of the epithelium? |
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Definition
Protection, absorption, secretion, ion transport, diffusion |
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Term
What are the 6 characteristics of the epithelium? |
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Definition
1. cellular (very little intercellular space/material) 2. Specialized cell junctions between cells (cell-cell contact) 3. Polarity, i.e. 2 distinct regions (apical, or top of cell, and basal, or bottom of cell) 4. Always associated w/ connective tissue 5. Avascular - no blood vessels (connective tissue houses blood vessels for nutrients and defensive cells) and innervative 6. Regenerative capability |
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Term
How does one classify epithelium? |
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Definition
They are classified by cell layers and the shape of the apical (top) cells. Layers, simple is one layer, and 2 or more is stratified. Shape, squamous is flat, cuboidal is cubic, columnar is taller than it is wide (nucleus is basal) |
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Term
List the types of epithelium |
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Definition
Simple squamous, simple cuboidal, simple columnar, stratified squamous, stratified cuboidal, stratified columnar, Pseudostratified columnar epithelium, and transitional epithelium |
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Term
What is special about pseudostratified columnar epithelium? |
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Definition
it doesn't look so, but all the cells do touch the basal lamina. It is primarily found in the respiratory and male reporductive systems. If located in the trachea, it has cilia. |
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Term
What is special about transitional epithelium? |
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Definition
It is found only lining the holow organs of the urinary system, allowing for stretching |
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Term
What are the primary uses for simple epithelium? |
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Definition
It is used for absorption, secretion and ion transport |
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Term
What is the primary use for stratified epithelium? |
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Definition
it is a protective tissue |
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Term
Where are stratified cuboidal and columnar epithelium located? |
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Definition
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Term
What is endothelium and what does it do? |
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Definition
Endothelium is simple squamous epithelium, and lines the blood vessels, the hert and the lymphatic organs |
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Term
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Definition
it is a simple squamous epithelium, which is part of the serous membrane in the ventral abdomen. |
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Term
What are the two types of stratified squamous epithelium? Where are they found? |
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Definition
Dry and moist, dry being the skin and are distinguished by their lack of nuclei in the apical cells. Moist has nuclei in it's apical cells and lines the mouth esophagus, etc. |
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Term
Explain the difference between covers and lines in anatomical terms of an epithelium? |
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Definition
Covers means it's on the outside, while lines means it's on the inside next to the lumen |
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Term
What is unique to the transitional epithelium? |
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Definition
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Term
Surfacing epithelium vs glandular epithelium? |
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Definition
simple stratified Makes and secretes a product |
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Term
Endocrine Glands vs Exocrine Glands |
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Definition
Endocrine glands secrete product (hormone) into the Extra Cellular Matrix (ECM) and/or in the blood vessels. Exocrine glands secrete their product onto the surface of epithelial cells, multicellular glands secrete via a duct. |
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Term
What is required for a multicellular exocrine gland? |
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Definition
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Term
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Definition
it is a cell that secretes Mucus, Mucin disolved in water. Mucin is a glycoprotein. |
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Term
What are the 2 basic parts of multicellular exocrine glands? |
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Definition
The secretory unit which makes the product (can be tubular or alveolar), and the duct which is the passage way for the product (can be simple, i.e. no branches, or compound, i.e. branching) |
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Term
What are the 3 surfaces of epithelium, and what specializations may each have? |
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Definition
Apical is the top of the cell, which may have cilia and microvilli Basal is the base of the cell which is attached to the basal lamina, which is a filter that provides support. It is on a reticular lamina (layer of reticular fibers) and both are known as the basement membrane. Lateral is the sideof the cell which may have cell junctions. |
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Term
What are microvilli and cilia, and what are their function? |
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Definition
Microvili are short fingerlike projections of the cell membrane used to increase the surfaces areas and therefore absorption and ion transport. Cilia are long fingerlike projections, which are more motile, and composed of an organized core of microtubules. they are used to move more material over/across the surface of the epithelium. |
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Term
What are the Cell junctions and their function? |
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Definition
Tight junction (zonula occludens) is the most apical and goes around the circumference of the cell, preventing passage of material between neighboring cells
Zonula Adherans is below the zonula occludens, goes around circ of cell, and prevents cells from separating, involves actin/microfilaments Desmosornes is located anywhere, but forms spot welds, and is the toughest of all junctions located in the areas where separation is likely. It is made ofKeratin (an intermediate filament) Gap Junctions is where proteins between 2 adjacent cells form a channel between adjacent cells for ion transport. |
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Term
What is the basic organization of connective tissue? |
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Definition
It has very few cells, has abundant Extra Cellular Matrix (ECM), and has no cell cell junctions. It contains fibers (proteins: callogen, reticular, and elastic) and ground substance (Protein and carbohydrates) |
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Term
What are the two types of connective tissue? |
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Definition
Connective tissue proper, which is either loose (areolar) CT which has the widest distribution and always associated with epithelium and surrounds BV and nerves, or dense CT (which has an abundance of callogen fibers) and Specialized connective tissue, which always have a special extra cellular matrix (like bone) |
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Term
What is the purpose of callogen fibers? |
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Definition
It is the toughest fiber provides tensile strengh (and stains pink) |
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Term
What is the purpose of reticular fibers? |
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Definition
they form a delicate network for support |
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Term
What is the purpose of the elastic fibers? |
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Definition
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Term
What are the functions of Ground substance? |
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Definition
The gel like protein and carbohydrate mix provides a physical barrier, holds tissue fluid that allows for diffusion of nutrients and waste. |
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Term
What is the purpose of Fibroblast? |
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Definition
It makes the fibers and ground substance that form the ECM in CT proper |
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Term
What are the defensive cells? |
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Definition
the mast cell (contains granules of histamine) mediates inflamation the macrophage is a phagocyte the plasma cell makes and secretes antibodies the white blood cells: neutrophil, lymphocyte, and eosinophil The Adipocyte (Fat cell) stores fat (energy) |
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Term
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Definition
it makes blood vessels more permeable, so they leak, alleviating some swelling |
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Term
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Definition
Proteins that are specific to certain antigens (foreign materials) |
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Term
What are the types and characteristics of Dense CT? |
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Definition
The abundance of fibers (callogen) the two types of Dense CT are irregular and regular, regular has organized callogen into one dierction to resist pull from 1 direction (tendons and ligaments are regular) Irregular has callogen which is not organized in 1 direction, which resists pulling in all directions (like the dermis of the skin and organ capsules) |
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Term
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Definition
Epithelium has mostly cells and very little ECM, while CT has few cells and alot of ECM, consisting of fibers and ground substance. |
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Term
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Definition
All connective tissue arises from embryonic tissue-mesenchyme (mesoderm) |
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Term
What are the specialized CT's? why are they special? |
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Definition
Bone, cartilage, and blood, because they have unique ECM's |
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Term
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Definition
Areolar LCT is under the epithelium surrounded by blood vessels and nerves Dense CT has an abundance of callogen fibers |
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Term
What are some examples of Loose Connective Tissue? |
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Definition
Adipose tissue and reticular CT |
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Term
What are the types of Dense connective tissue, and how are they utilized? |
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Definition
Dense irregular CT has unorganized callogen, which allows for it to be pulled in all directions. Dense Regular CT has callogen organized in one direction, which allows for pulling along that direction. Elastic CT is a type of DCT with an abundance of elstiv fibers, but has limited distribution in the body. |
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Term
Covering and lining membranes are made of ___________ |
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Definition
epithelium, with CT under it |
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Term
Describe the Cutaneous membrane |
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Definition
it is the Skin, dry, the epithelium is stratified squamous Keratinized epithelium, it's CT consists of LCT and DCT |
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Term
Describe the mucous membrane |
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Definition
Mucous membranes=mucosa, is moist and named for it's location, not it's product. It lines hollow organs/systems that eventually open to outside the body. (i.e. digestive, respiratory, urinary, and reproductive systems) It varies in it's epithelium depending on the system, which is above areolar LCT. In the case of Mucous membranes, the LCT is known as the LAMINA PROPRIA. |
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Term
Describe the Serous Membrane |
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Definition
AKA Serosa, the serous membrane is wet since it produces serous fluid, and is found in the ventral body cavity only, lining the body wall and covers most visceral organs. |
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