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Analgesia
pharm test 2
33
Nursing
Graduate
05/30/2012

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Term
pain control analgesics
Definition
The physical component of pain involves the nerve pathways and the brain.
The psychological component or the emotional response to pain is the product of factors such as the individual’s anxiety level, previous pain experience, age, sex, and culture.
Term
acute pain
Definition
less than 6 mo in duration. severe discomfort, uncomfy sensation. easier to treat and control- sudden onset, usually subsides with treatment.
Term
chronic pain
Definition
6 mo or greater. much more diff. to treat, persistant reocurring pain. disease process or injury
Term
visceral pain
Definition
originates from the smooth muscle or SNS innervated organ system. refer pain (left arm ache in MI), difficult to localize as it could be dull ache.
Term
somatic pain
Definition
arises from the skeletal muscles, usually localized, constant, aching or throbbing,
Term
neuropathic pain
Definition
caused by peripheral nerve injury and not stiumluation. hardest to control. have to fix problem to fix pain. pins and needles (paresthesia) burning/shooting/tingling
Term
paresthesia
Definition
pins and needles
Term
Opiod receptors
Definition
Mu, Kappa, Delta
Term
Mu opiod receptor
Definition
most important. response to these being stimulated is analgesia, resp depression, euphoria, and sedation. component to physical dependence.
Term
kappa receptors
Definition
can produce analgesia and sedation. dont cause breathing issues.
Term
delta
Definition
the opiod analgesics do not effect these. no meds effect it directly.
Term
agonist
Definition
to do. binds with receptor to produce the maximum response.
Term
partial agonist
Definition
this produces a partial response
Term
antagonist
Definition
to block
Term
most common opiod analgesic
Definition
morphine
Term
moderate pain #s
Definition
3-6
Term
morphine how it works
Definition
This produces it’s effects by combining with receptor sites in the brain called opioid receptors.
Term
morphine uses
Definition
Uses (Indications):
Indicated for severe pain
Utilized with cardiac patients due to the vasodilitation properties. This helps decrease the hearts workload and increase the oxygen available
Term
low dose morphine
Definition
may be used to depress the cough center
Term
Morphine administration
Definition
Orally
IM
IV
SQ
Epidurally
Intrathecally
rectally
Term
Other strong opioid agonist medications:
Definition
Meperidine (Demerol)
Fentanyl (Duragesic)
Hydromorphone (Dilaudid)
Term
strong opioid agonist AR
Definition
Seizures
Pruritus
Skin rash
Facial edema
Breathing difficulties
Respiratory depression
Confusion
Tachycardia
Term
Pruritus
Definition
intense itching
Term
strong opioid agonist SE
Definition
Vertigo, faintness, light-headedness
Fatigue, sleepiness, N & V, increased sweating, constipation and hypotension.
Term
moderate to strong opiods
Definition
Codeine
Propoxyphene (Darvon, Darvocet)
Hydrocodone (Lortab, Vicodin, Vicoprofen)
Oxycodone (Percodan, Percocet, OxyContin)
Many of these medications above are combined with either ASA, Acetaminophen or Ibuprofen, therefore, be cautious of overdoses.
pt will not need OTC pain meds. increase H2) consumption, these constipate
Term
Opioid Agonist-Antagonist agents
Definition
if a patient is addicted this will to opiod- this will cause immediate withdrawl.
Opioid Agonist-Antagonist agents
Most patient’s are taking an OTC analgesic for everyday problems, make sure you check for OD possibilities, due to combinations, and adverse drug interactions.
Term
PCA pumps
Definition
patient control analgesia. proven this is best for post-op pts.
Term
Opiod Antagnoists
Definition
"THE ANTIDOTE", USE FOR OD/Suicide attempts
To reverse the post-operative effects of analgesics
To reverse potentially life-threatening AR’s
NARCAN- most pop
Anytime you are giving an opioid analgesic, you must be familiar with the antidotes and exactly where to obtain and how to use them correctly.
Term
Non-opioid analgesics:
Definition
These are used for mild to moderate pain.
Used for acute and/or chronic pain
They do not cause respiratory depression, dependence or abuse and are not regulated under the Controlled Substance Act
Major meds in this classification:
Tramadol (Ultram)-recently moved to a controlled substance status due mainly to abuse.
Term
The most common Side effects of long term med usage and gastric/GI upset are
Definition
Localized gastric pain
Bleeding from rectum (dark colored stool, bright red blood in stool/urine)
Gastric bleeding (may vomit or cough up dark or bright red blood)
Increased clotting time with long term aspirin or high dose aspirin usage.
Term
Opioid use in older adults
Definition
Cognitive impairment, dementia, and confusion may add to the barriers for pain assessment.
Liver and kidney impairment may reduce drug clearance
They may be likely to ask for less pain medicine because they do not want to be a bother.
Nonverbal cues are essential with this population.
Term
spitting up bright red blood
Definition
medical emergency- acute upper GI bleed
Term
spitting up dark blood
Definition
old upper GI bleed. non emergency
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