Term
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Definition
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Term
What dye will stain amyloid? |
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Definition
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Term
What type of birefringence occurs with amyloid and its characteristic dye? |
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Definition
yellow-green birefringence |
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Term
What type of protein structure is amyloid? |
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Definition
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Term
What occurs to the tissue and organs of a amyloidosis patient? |
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Definition
the tissue will atrophy, but the added amyloid will cause the organs themselves to enlarge |
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Term
What does the P component do for amyloid? |
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Definition
it is not actually amyloid but stabilizes it |
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Term
What part of amyloid does not stain with congo red? |
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Definition
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Term
WHere is the P component produced? |
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Definition
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Term
What are the two most common types of amyloidosis? |
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Definition
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Term
Which amyloidosis is due to plasma cell production of light chains? |
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Definition
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Term
Which is the primary amyloidosis and which is the secondary? |
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Definition
primary is AL
secondary is AA |
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Term
Which amyloidosis acompanies inflammatory process?A |
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Definition
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Term
Which form of amyloidosis commonly presents with renal disease? |
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Definition
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Term
Which amyloidosis leads to an enlarged tongue? |
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Definition
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Term
What amyloidosis is the acute phase reactant SAA found in? |
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Definition
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Term
Which amyloidosis is associated with Mediterranian Fever? |
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Definition
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Term
What does the Mediterranian Fever cause? |
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Definition
intermitten acute attacks of pain
usually abdominal pain |
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Term
Which amyloidosis is commonly associated with Rheumatoid arthritis? |
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Definition
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Term
What organ do you not want to biopsy in diagnosis of amyloidosis? Why? |
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Definition
liver due to severe bleeding risk |
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Term
What form of amyloidosis is due to transthyretic (preamyloid)? |
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Definition
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Term
How many forms of the disease are there in ATTR?
What are they? |
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Definition
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Term
What are the two types of cardiac ATTR and which is most common? |
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Definition
Senile (more common)
Familial |
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Term
Which form of cardiac ATTR is asymptomatic? What is usually present on autopsy? |
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Definition
Senile
enlarged left atrium |
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Term
What does transthyretin do? |
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Definition
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Term
How is amyloidosis diagnoised? |
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Definition
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